
US Patent No: 7,902,427
Number of patents in Portfolio can not be more than 2000
PUFA polyketide synthase systems and uses thereof
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Mar 8, 2011
Issued date -
Mar 21, 2007
filing date -
11/689,439
serial no -
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Abstract
, and biologically active fragments and homologues thereof. More particularly, this invention relates to nucleic acids encoding such PUFA PKS systems, to proteins and domains thereof that comprise such PUFA PKS systems, to genetically modified organisms (plants and microorganisms) comprising such PUFA PKS systems, and to methods of making and using the PUFA PKS systems disclosed herein. This invention also relates to genetically modified plants and microorganisms and methods to efficiently produce lipids enriched in various polyunsaturated fatty acids (PUFAs) as well as other bioactive molecules by manipulation of a PUFA polyketide synthase (PKS) system.
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First Claim
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International Classification(s)
Cited Art
| Patent Info | (Count) | # Cites | Year |
|---|---|---|---|
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| 5,130,242 Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids | 178 | 1990 | |
| 5,908,622 Food product containing thraustochytrium and/or schizochytrium microflora and an additional agricultural based ingredient | 68 | 1997 | |
| 6,566,583 Schizochytrium PKS genes | 63 | 1999 | |
| 7,001,772 Product and process for transformation of Thraustochytriales microorganisms | 55 | 2002 | |
| 7,247,461 Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof | 31 | 2002 | |
| 7,214,853 Schizochytrium PKS genes | 45 | 2002 | |
| 7,211,418 PUFA polyketide synthase systems and uses thereof | 51 | 2004 | |
| 7,217,856 PUFA polyketide synthase systems and uses thereof | 51 | 2004 | |
| 7,256,022 Pufa polyketide synthase systems and uses thereof | 45 | 2005 | |
| 7,256,023 PUFA polyketide synthase systems and uses thereof | 46 | 2005 | |
| 7,259,295 PUFA polyketide synthase systems and uses thereof | 45 | 2005 | |
| 7,271,315 PUFA polyketide synthase systems and uses thereof | 51 | 2006 | |
| 2007/0256,146 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
| 2007/0244,192 PLANT SEED OILS CONTAINING POLYUNSATURATED FATTY ACIDS | 52 | 2007 | |
| 2007/0270,494 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS | 48 | 2007 | |
| 2007/0266,455 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 26 | 2007 | |
| 2008/0026,435 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
| 2008/0026,436 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 26 | 2007 | |
| 2008/0026,437 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 26 | 2007 | |
| 2008/0032,296 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 25 | 2007 | |
| 2008/0026,438 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 35 | 2007 | |
| 2008/0026,439 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 35 | 2007 | |
| 2008/0026,440 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 36 | 2007 | |
| 2008/0032,351 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 36 | 2007 | |
| 2008/0038,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 35 | 2007 | |
| 2008/0022,422 CHIMERIC PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 49 | 2007 | |
| 2008/0148,433 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
| 2008/0038,791 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 35 | 2007 | |
| 2008/0038,792 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 35 | 2007 | |
| 2008/0044,867 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 36 | 2007 | |
| 2008/0038,793 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
| 2008/0038,794 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 41 | 2007 | |
| 2008/0038,795 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
| 2008/0038,796 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 41 | 2007 | |
| 2008/0038,797 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
| 2008/0040,822 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
| 2008/0044,868 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 41 | 2007 | |
| 2008/0044,869 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 41 | 2007 | |
| 2008/0044,871 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
| 2008/0044,872 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
| 2008/0044,873 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
| 2008/0050,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 40 | 2007 | |
| 2008/0032,338 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 26 | 2007 | |
| 2008/0032,367 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 26 | 2007 | |
| 2008/0032,368 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 25 | 2007 | |
| 2008/0032,369 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 26 | 2007 | |
| 2008/0038,798 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 26 | 2007 | |
| 2008/0038,799 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 26 | 2007 | |
| 2008/0044,874 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 26 | 2007 | |
| 2008/0050,791 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 26 | 2007 | |
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| 5,246,841 Microbial process for production of eicosapentaenoic acid | 60 | 1991 | |
| 5,683,898 Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid | 64 | 1995 | |
| 5,798,259 Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid | 52 | 1996 | |
|
|
|||
| 6,677,145 Elongase genes and uses thereof | 50 | 2001 | |
| 7,208,590 Genes involved in polyketide synthase pathways and uses thereof | 20 | 2003 | |
|
|
|||
| 2004/0172,682 Production of very long chain polyunsaturated fatty acids in oilseed plants | 52 | 2004 | |
| 7,125,672 Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts | 60 | 2004 | |
|
|
|||
| 2008/0038,378 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 35 | 2007 | |
| 2008/0038,379 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 44 | 2007 | |
|
|
|||
| 5,639,790 Plant medium-chain thioesterases | 93 | 1993 | |
| 6,140,486 Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants | 81 | 1998 | |
|
|
|||
| 7,087,432 Fad4, Fad5, Fad5-2 and Fad6, novel fatty acid desaturase family members and uses thereof | 44 | 2001 | |
|
|
|||
| 6,033,883 Production of polyketides in bacteria and yeast | 76 | 1997 | |
|
|
|||
| 2005/0089,865 Delta 6 desaturases from primulaceae, expressing plants and pufa-containing oils | 52 | 2004 | |
|
|
|||
| 2004/0005,672 Heterologous production of polyketides | 51 | 2003 | |
|
|
|||
| 2004/0139,498 Fatty acid elongase 3-ketoacyl CoA synthase polypeptides | 44 | 2004 | |
|
|
|||
| 6,503,706 Method for identifying human and animal cells having an unlimited proliferation of tumor-formation potential | 47 | 1996 | |
|
|
|||
| 2007/0245,431 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS | 51 | 2007 | |
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|
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| 2008/0044,870 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF | 42 | 2007 | |
|
|
|||
| 5,672,491 Recombinant production of novel polyketides | 159 | 1994 | |
|
|
|||
| 2005/0164,192 Transgenic plants expressing enzymes involved in fatty acid biosynthesis | 92 | 2005 | |
|
|
|||
| 2004/0010,817 Plant acyl-CoA synthetases | 44 | 2003 | |
|
|
|||
| 5,310,242 Portable infant seat | 56 | 1992 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 3.5 Year Payment | $1600.00 | $800.00 | $400.00 | Sep 8, 2014 |
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Sep 8, 2018 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Sep 8, 2022 |
| Fee | Large entity fee | small entity fee | micro entity fee |
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