US Patent No: 7,902,427

Number of patents in Portfolio can not be more than 2000

PUFA polyketide synthase systems and uses thereof

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Abstract

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, and biologically active fragments and homologues thereof. More particularly, this invention relates to nucleic acids encoding such PUFA PKS systems, to proteins and domains thereof that comprise such PUFA PKS systems, to genetically modified organisms (plants and microorganisms) comprising such PUFA PKS systems, and to methods of making and using the PUFA PKS systems disclosed herein. This invention also relates to genetically modified plants and microorganisms and methods to efficiently produce lipids enriched in various polyunsaturated fatty acids (PUFAs) as well as other bioactive molecules by manipulation of a PUFA polyketide synthase (PKS) system.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
DSM IP ASSETS B.V.6411 TE HEERLEN1113

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Metz, James G Longmont, US 80 2525
Weaver, Craig A Boulder, US 49 1566
Zirkle, Ross Longmont, US 40 721

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
5,310,242 Portable infant seat 60 1992
 
UNIVERSITY OF YORK (1)
2005/0164,192 Transgenic plants expressing enzymes involved in fatty acid biosynthesis 132 2005
 
E. I. DU PONT DE NEMOURS AND COMPANY (2)
2004/0172,682 Production of very long chain polyunsaturated fatty acids in oilseed plants 68 2004
7,125,672 Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts 73 2004
 
MARTEK BIOSCIENCES CORPORATION (2)
2008/0038,378 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 39 2007
2008/0038,379 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 48 2007
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (1)
5,672,491 Recombinant production of novel polyketides 199 1994
 
Biotica Technology Limited (1)
6,033,883 Production of polyketides in bacteria and yeast 81 1997
 
ROCHE DIAGNOSTICS GMBH (1)
6,503,706 Method for identifying human and animal cells having an unlimited proliferation of tumor-formation potential 51 1996
 
SUPERMEDIA LLC (1)
2008/0044,870 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
 
IACR-Rothamsted (1)
2005/0089,865 Delta 6 desaturases from primulaceae, expressing plants and pufa-containing oils 64 2004
 
Kosan Biosciences, Inc. (1)
2004/0005,672 Heterologous production of polyketides 55 2003
 
MONSANTO COMPANY (2)
5,639,790 Plant medium-chain thioesterases 105 1993
6,140,486 Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants 98 1998
 
ABBOTT LABORATORIES (2)
6,677,145 Elongase genes and uses thereof 65 2001
7,208,590 Genes involved in polyketide synthase pathways and uses thereof 24 2003
 
DSM IP ASSETS B.V. (50)
5,130,242 Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids 269 1990
5,908,622 Food product containing thraustochytrium and/or schizochytrium microflora and an additional agricultural based ingredient 79 1997
6,566,583 Schizochytrium PKS genes 78 1999
7,001,772 Product and process for transformation of Thraustochytriales microorganisms 77 2002
7,247,461 Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof 41 2002
7,214,853 Schizochytrium PKS genes 56 2002
7,211,418 PUFA polyketide synthase systems and uses thereof 65 2004
* 7,217,856 PUFA polyketide synthase systems and uses thereof 64 2004
7,256,022 Pufa polyketide synthase systems and uses thereof 50 2005
7,256,023 PUFA polyketide synthase systems and uses thereof 51 2005
7,259,295 PUFA polyketide synthase systems and uses thereof 50 2005
7,271,315 PUFA polyketide synthase systems and uses thereof 63 2006
2007/0256,146 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 45 2007
2007/0244,192 PLANT SEED OILS CONTAINING POLYUNSATURATED FATTY ACIDS 65 2007
2007/0270,494 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS 62 2007
2007/0266,455 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0026,435 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0026,436 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0026,437 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0032,296 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 26 2007
2008/0026,438 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 36 2007
2008/0026,439 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 37 2007
2008/0026,440 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 38 2007
2008/0032,351 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 38 2007
2008/0038,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 36 2007
2008/0022,422 CHIMERIC PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 60 2007
2008/0148,433 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0038,791 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 37 2007
2008/0038,792 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 36 2007
2008/0044,867 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 38 2007
2008/0038,793 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0038,794 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0038,795 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0038,796 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0038,797 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0040,822 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 46 2007
2008/0044,868 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0044,869 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0044,871 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0044,872 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0044,873 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0050,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0032,338 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0032,367 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0032,368 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 26 2007
2008/0032,369 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0038,798 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0038,799 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0044,874 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0050,791 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
 
SAGAMI CHEMICAL RESEARCH CENTER (3)
5,246,841 Microbial process for production of eicosapentaenoic acid 69 1991
5,683,898 Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid 76 1995
5,798,259 Gene coding for eicosapentaenoic acid synthesizing enzymes and process for production of eicosapentaenoic acid 64 1996
 
Bioriginal Food & Science Corp. (1)
7,087,432 Fad4, Fad5, Fad5-2 and Fad6, novel fatty acid desaturase family members and uses thereof 59 2001
 
SEMBIOSYS GENETICS INC. (1)
2007/0245,431 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS 69 2007
 
WASHINGTON STATE UNIVERSITY (1)
2004/0010,817 Plant acyl-CoA synthetases 49 2003
 
Miami University, an Ohio corporation (1)
2004/0139,498 Fatty acid elongase 3-ketoacyl CoA synthase polypeptides 48 2004
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
DSM IP ASSETS B.V. (5)
8,940,884 Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof 0 2010
* 2010/0266,564 Polyunsaturated Fatty Acid Synthase Nucleic Acid Molecules and Polypeptides, Compositions, and Methods of Making and Uses Thereof 4 2010
* 2011/0167,508 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 5 2010
8,309,796 Chimeric PUFA polyketide synthase systems and uses thereof 0 2011
8,859,855 Chimeric PUFA polyketide synthase systems and uses thereof 0 2012
* Cited By Examiner

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