Method for identifying peptides in a biological sample
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United States of America Patent
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Mar 15, 2011
Grant Date -
Dec 22, 2005
app pub date -
Apr 26, 2005
filing date -
Apr 27, 2004
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention provides a method for isolating a cargo peptide from a sample containing a cargo peptide-carrier protein complex. The method involves contacting a sample comprising a cargo peptide-carrier protein complex with a binding moiety selective for the carrier protein, under conditions wherein the carrier protein binds non-covalently to the binding moiety, and wherein the binding moiety is attached to a support, dissociating the cargo peptide from the cargo peptide-carrier protein complex, wherein the carrier protein remains bound to the binding moiety, and collecting the cargo peptide, whereby the cargo peptide is isolated from the sample.
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