Mass spectrometry with laser ablation
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United States of America Patent
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Mar 22, 2011
Grant Date -
Jun 5, 2008
app pub date -
Nov 21, 2007
filing date -
Dec 4, 2006
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Abstract
A mass spectrometric analysis of surface material is performed by vaporizing the surface material with pulses of laser light and then collecting the vaporized material by dissolving it in a liquid. The liquid with the dissolved material is then fed to an ionization process, preferably an electrospray ionization process. The resulting ions are then analyzed with a mass spectrometer. The method is particularly suited for use with imaging mass spectrometry.
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