Capture moieties for nucleic acids and uses thereof
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United States of America Patent
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Mar 29, 2011
Grant Date -
Feb 28, 2008
app pub date -
May 25, 2007
filing date -
Jun 6, 2000
priority date (Note) -
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Abstract
A unimolecular probe for hybridization to a molecule comprising a target nucleic acid sequence, the probe includes: a first nucleic acid sequence complementary to the target sequence (target-binding sequence); and a second nucleic acid sequence complementary to a portion of the first nucleic acid sequence and capable of hybridization therewith to form a first intramolecular duplex. In use, the target and target-bind sequence hybridize to form a duplex. A probe can be used to detect a molecule containing the target sequence, act as a primer for synthesis or amplification, etc.
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