Anti-IL-6 monoclonal antibodies
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United States of America Patent
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Apr 5, 2011
Grant Date -
Mar 27, 2008
app pub date -
Aug 3, 2007
filing date -
Aug 3, 2006
priority date (Note) -
Expired
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Abstract
The present invention provides novel monoclonal antibodies that bind specifically to IL-6. The antibodies of the invention comprise a variable heavy chain (VH) region selected from any of the VH regions disclosed herein as well as amino acid variants thereof, and/or a variable light chain (VL) region selected from any of the VL regions disclosed herein as well as amino acid variants thereof. The invention also provides methods of treating diseases and disorders associated with IL-6 expression and/or activity.
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