Antibiotic/s containing bone substitute material with sustained active substance release
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United States of America Patent
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Apr 12, 2011
Grant Date -
Jun 15, 2006
app pub date -
Dec 5, 2005
filing date -
Dec 15, 2004
priority date (Note) -
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Abstract
Antibiotic/s containing bone substitute material is described which is characterized in that it is composed of a compacted mixture of granules of calcium sulfate dihydrate, calcium carbonate and at least one representative of the aminoglycoside antibiotics, lincosamide antibiotics, glycopeptide antibiotics, macrolide antibiotics, ketolide antibiotics, the nitroimidazoles, the fluorochinolone antibiotics and the oxazolidinone antibiotics, the steroid antibiotics, the antiseptic agents and the fungicidal/fungistatic antibiotics which are partly or entirely sheathed with a layer of glycerol tripalmitate and/or glycerol tristearate and/or glycerol trilaurate and/or 1-hexadecyl alcohol which connects the granules with each other.
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