Use of CPG oligodeoxynucleotides to induce angiogenesis
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United States of America Patent
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May 3, 2011
Grant Date -
Jan 31, 2008
app pub date -
Aug 15, 2007
filing date -
Dec 20, 2001
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Abstract
This disclosure provides a method of inducing production of vascular endothelial growth factor by a cell. The method includes contacting the cell with a CpG oligonucleotide, thereby inducing the production of vascular endothelial growth factor by the cell. The disclosure further provides a method inducing neovascularization in a tissue. This method includes comprising introducing a CpG oligodeoxynucleotide into an area of the tissue wherein the formation of new blood vessels is desired, thereby inducing neovascularization in the area of the tissue.
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