Method of delivering a drug using a medical device with a coating comprising a self-assembled molecular structure

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United States of America Patent

PATENT NO 7941212
APP PUB NO 20080154232A1
SERIAL NO

12043891

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method for local delivery of a drug is provided. The method comprises the acts of (a) implanting a medical device carrying a drug-containing coating in a patient for the sustained local delivery of the drug, wherein at least a portion of the coating is transformed from crystalline structure to amorphous structure; and (b) applying an electric current for an interval of time to the device for increasing the rate of release of the drug, wherein the coating is further transformed from crystalline structure to amorphous structure; and (c) terminating the current after an interval of time, wherein at least a portion of the amorphous structure in the coating is at least partially restored to crystalline structure.

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Patent Owner(s)

  • ADVANCED CARDIOVASCULAR SYSTEMS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Claude, Charles D Santa Clara, US 47 1087
Kwok, Connie S Sunnyvale, US 11 133

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