Sinus delivery of sustained release therapeutics
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United States of America Patent
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May 31, 2011
Grant Date -
Mar 17, 2011
app pub date -
Sep 15, 2010
filing date -
Mar 14, 2003
priority date (Note) -
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Abstract
The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape, density, viscosity, and/or mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic, e.g., an antibiotic, a steroidal anti-inflammatory agent, or both. The biodegradable implants may take various forms, such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.
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