8-chloro-2,3-benzodiazepine derivatives
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United States of America Patent
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Jun 14, 2011
Grant Date -
Jun 26, 2008
app pub date -
Jul 29, 2004
filing date -
Aug 4, 2003
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention relates to new 8-chloro-2,3-benzodiazepine derivatives of the general formula (I), wherein R stands for a lower alkyl group or a group of the general formula —NH—R′, wherein R′ stands for a lower alkyl or a lower cycloalkyl group), and pharmaceutically acceptable acid addition salts thereof. The invention also encompasses a process for the preparation of said compounds, pharmaceutical compositions containing them and new intermediates useful for the preparation of the new 8-chloro-2,3-benzodiazepine derivatives. The compounds according to the invention possess AMPA/kainate receptor inhibiting activity.
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