Protein formulations for use at elevated temperatures
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United States of America Patent
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Jun 21, 2011
Grant Date -
May 27, 2010
app pub date -
Jan 28, 2010
filing date -
Jun 29, 2007
priority date (Note) -
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Abstract
Liquid formulations of bone morphogenetic proteins are provided for prolonged use at elevated temperatures. More specifically, the invention relates to liquid formulations comprising rhGDF-5, trehalose, and one or more biocompatible excipients that provide stability to the protein for at least 30 days at temperatures up to body temperature.
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