US Patent No: 7,968,119

Number of patents in Portfolio can not be more than 2000

Tamper-proof narcotic delivery system

ALSO PUBLISHED AS: 20030026838

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Abstract

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A composition for oral, transdermal or subdermal administration to a subject is described. The composition contains: (a) an agonist component; (b) an antagonist component containing at least one antagonist and having a delayed time of release; and (c) an immediate release antagonist removal component, where the subject includes a gastrointestinal tract and the antagonist removal component is present in an amount sufficient to substantially remove the antagonist component from the gastrointestinal tract of the subject before the time of release of the antagonist component. The composition may be delivered to the subject by a method which includes the step of administering the composition orally, transdermally or subdermally to the subject. When the composition of the present invention is administered orally, the method of the present invention may include the step of administering a potassium compound to the subject.

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First Claim

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Patent Owner(s)

  • Assignment data not available. Check USPTO

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Farrell, John J Norwood, MA 16 137

Cited Art Landscape

Patent Info (Count) # Cites Year
 
PURDUE PHARMA L.P. (9)
5,958,452 Extruded orally administrable opioid formulations 123 1997
6,228,863 Method of preventing abuse of opioid dosage forms 115 1998
6,277,384 Opioid agonist/antagonist combinations 84 1998
6,231,886 Methods of providing sustained treatment with opioids 7 1999
6,335,033 Melt-extrusion multiparticulates 64 1999
6,261,599 Melt-extruded orally administrable opioid formulations 103 1999
6,375,957 Opioid agonist/opioid antagonist/acetaminophen combinations 109 2000
6,696,088 Tamper-resistant oral opioid agonist formulations 88 2001
2002/0058,673 Opioid agonist/opioid antagonist/acetaminophen combinations 31 2001
 
GLYCOBIOSCIENCES INC. (2)
5,716,631 Long acting narcotic analgesics and antagonists 6 1996
5,709,883 Long acting narcotic analgesics and antagonists 10 1997
 
The United States of America as represented by the Secretary of the Army (2)
5,834,477 Opiate analgesic formulation with improved safety 38 1994
6,217,911 sustained release non-steroidal, anti-inflammatory and lidocaine PLGA microspheres 29 1996
 
VALEANT INTERNATIONAL BERMUDA (2)
5,518,730 Biodegradable controlled release flash flow melt-spun delivery system 168 1992
6,013,280 Immediate release dosage forms containing microspheres 17 1997
 
ALZA CORPORATION (1)
5,540,912 Viscous suspensions of controlled-release drug particles 81 1994
 
BAKER HUGHES INCORPORATED (1)
6,130,258 Polyvalent metal cations in combination with dithiocarbamic acid compositions as board spectrum demulsifiers 1 1998
 
BAYLOR UNIVERSITY (1)
5,855,915 Tablets or biologically acceptable implants for long-term antiinflammatory drug release 16 1996
 
BRISTOL-MYERS SQUIBB COMPANY (1)
4,457,933 Prevention of analgesic abuse 95 1981
 
CERTA DOSE, INC. (1)
6,132,416 Universal medication dosing system 13 1998
 
CHILDREN'S MEDICAL CENTER CORPORATION (1)
4,391,797 Systems for the controlled release of macromolecules 111 1981
 
DEXCEL PHARMA TECHNOLOGIES LTD. (1)
5,840,332 Gastrointestinal drug delivery system 67 1996
 
EDT PHARMA HOLDINGS (1)
6,066,339 Oral morphine multiparticulate formulation 13 1997
 
EURO-CELTIQUE S.A. (1)
6,068,855 Pharmaceutical composition containing a fusible carrier and method for producing the same 60 1997
 
FUISZ TECHNOLOGIES LTD. (1)
6,020,002 Delivery of controlled-release system(s) 16 1997
 
HISAMITSU PHARMACEUTICAL CO., INC. (1)
5,820,877 Percutaneously administrable patch preparation 9 1996
 
ICN HUNGARY RT. (1)
5,317,022 Pharmaceutical composition and use 54 1992
 
INTENSIVE NARCOTIC DETOXIFICATION CENTERS OF AMERICA, LLC (1)
5,922,705 Rapid narcotic detoxification 3 1998
 
IPSEN PHARMA S.A.S. (1)
5,569,467 Process for the preparation of microballs and microballs thus obtained 15 1994
 
JANSSEN PHARMACEUTICA N.V. (1)
5,792,477 Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent 82 1997
 
LUMARA HEALTH IP LTD. (1)
6,214,379 Maximizing effectiveness of substances used to improve health and well being 22 1999
 
Minnesota Mining and Manufacturing Company (1)
5,698,217 Transdermal drug delivery device containing a desiccant 22 1995
 
MYLAN TECHNOLOGIES, INC. (1)
5,679,373 Process of assembling a transdermal patch incorporating a polymer film incorporated with an active agent 17 1995
 
NAPP PHARMACEUTICAL GROUP LIMITED (1)
6,326,027 Controlled release formulation 66 1995
 
NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT (1)
5,780,589 Ultraselective opioidmimetic peptides and pharmacological and therapeutic uses thereof 17 1994
 
ORTHO-MCNEIL PHARMACEUTICAL, INC. (1)
4,906,463 Transdermal drug-delivery composition 80 1988
 
PHARMACIA & UPJOHN (1)
5,885,486 Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof 19 1996
 
QUADRANT DRUG DELIVERY LIMITED (1)
5,958,455 Oral solid dosage forms, methods of making same and compositions thereof 30 1996
 
RECKITT BENCKISER HEALTHCARE (UK) LIMITED (1)
4,582,835 Analgesic compositions 98 1984
 
SIMON, DAVID LEW (1)
5,783,583 17-(cyclopropylmethyl)-4,5alpha-epoxy-6-methylenemorphinan-3,14-diol, hydrochloride salt for the purpose of rapid narcotic detoxification 7 1996
 
SS Pharmaceutical Co., Ltd. (1)
5,496,561 Controlled release-initiation and controlled release-rate pharmaceutical composition 18 1994
 
TEVA PHARMACEUTICAL INDUSTRIES LTD. (1)
5,609,886 Microspheres for the controlled release of water-soluble substances and process for preparing them 13 1995
 
The Lynx Project Limited (1)
6,310,072 Production of analgesic synergy by co-administration of sub-analgesic doses of a MU opioid agonist and a kappa-2 opioid agonist 44 1997
 
The Rockefeller University (1)
4,987,136 Method for controlling gastrointestinal dysmotility 106 1986
 
UNIVERSITY OF CHICAGO, THE (1)
5,972,954 Use of methylnaltrexone and related compounds 87 1997
 
VINCENT C. GIAMPAPA (1)
5,494,677 Tissue-specific implantable therapeutic agent delivery system 6 1993
 
Other [Check patent profile for assignment information] (4)
5,580,569 Article for tissue-specific delivery of therapeutic agents 11 1993
5,512,587 Method for treating opiate withdrawal 1 1994
5,811,451 Pharmaceutical compositions comprising an opiate antagonist and calcium salts, their use for the treatment of endorphin-mediated pathologies 27 1996
5,919,473 Methods and devices for delivering opioid analgesics to wounds via a subdermal implant 68 1997

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
PURDUE PHARMA L.P. (1)
8,758,825 Sequestered antagonist formulations 0 2013

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