US Patent No: 7,970,448

Number of patents in Portfolio can not be more than 2000

Device and method for determining analyte levels

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ALSO PUBLISHED AS: 20100204559
ATTORNEY / AGENT: (SPONSORED)
 

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Abstract

Devices and methods for determining analyte levels are described. The devices and methods allow for the implantation of analyte-monitoring devices, such as glucose monitoring devices, that result in the delivery of a dependable flow of blood to deliver sample to the implanted device. The devices comprise a unique microarchitectural arrangement in the sensor region that allows accurate data to be obtained over long periods of time.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
DEXCOM, INC.SAN DIEGO, CA166

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rhodes, Rathbun K Madison, WI 39 3879
Shults, Mark C Madison, WI 51 6138
Updike, Stuart J Madison, WI 34 4240

Cited Art

Patent Info (Count) # Cites Year
 
DEXCOM, INC. (85)
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4,994,167 Biological fluid measuring device 324 1988
6,001,067 Device and method for determining analyte levels 418 1997
6,741,877 Device and method for determining analyte levels 292 2000
2003/0032,874 Sensor head for use with implantable devices 283 2001
6,702,857 Membrane for use with implantable devices 289 2001
6,862,465 Device and method for determining analyte levels 241 2001
7,226,978 Techniques to improve polyurethane membranes for implantable glucose sensors 210 2002
7,134,999 Optimized sensor geometry for an implantable glucose sensor 337 2003
7,192,450 Porous membranes for use with implantable devices 261 2003
7,110,803 Device and method for determining analyte levels 244 2003
2004/0186,362 Membrane for use with implantable devices 250 2004
2005/0242,479 IMPLANTABLE ANALYTE SENSOR 181 2004
2005/0245,795 IMPLANTABLE ANALYTE SENSOR 268 2004
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2005/0031,689 Biointerface membranes incorporating bioactive agents 267 2004
2005/0033,132 Analyte measuring device 222 2004
2006/0015,020 SYSTEMS AND METHODS FOR MANUFACTURE OF AN ANALYTE-MEASURING DEVICE INCLUDING A MEMBRANE SYSTEM 266 2004
2005/0051,427 Rolled electrode array and its method for manufacture 172 2004
2005/0056,552 Increasing bias for oxygen production in an electrode system 172 2004
7,074,307 Electrode systems for electrochemical sensors 332 2004
7,108,778 Electrochemical sensors including electrode systems with increased oxygen generation 290 2004
7,379,765 Oxygen enhancing membrane systems for implantable devices 134 2004
2005/0176,136 AFINITY DOMAIN FOR ANALYTE SENSOR 189 2004
2005/0143,635 Calibration techniques for a continuous analyte sensor 249 2004
7,081,195 Systems and methods for improving electrochemical analyte sensors 177 2004
2005/0177,036 Device and method for determining analyte levels 115 2004
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7,711,402 Device and method for determining analyte levels 113 2004
2005/0181,012 Composite material for implantable device 110 2005
7,136,689 Device and method for determining analyte levels 180 2005
7,364,592 Biointerface membrane with macro-and micro-architecture 128 2005
2006/0019,327 TRANSCUTANEOUS ANALYTE SENSOR 225 2005
2006/0020,186 TRANSCUTANEOUS ANALYTE SENSOR 240 2005
2006/0036,140 TRANSCUTANEOUS ANALYTE SENSOR 227 2005
2006/0016,700 TRANSCUTANEOUS ANALYTE SENSOR 234 2005
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2006/0142,651 Analyte sensor 49 2006
2006/0155,180 Analyte sensor 125 2006
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2007/0045,902 Analyte sensor 87 2006
2007/0027,370 Analyte sensor 74 2006
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2007/0032,718 Device and method for determining analyte levels 74 2006
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2007/0163,880 ANALYTE SENSOR 157 2007
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2008/0045,824 SILICONE COMPOSITION FOR BIOCOMPATIBLE MEMBRANE 146 2007
2008/0021,666 SYSTEM AND METHODS FOR PROCESSING ANALYTE SENSOR DATA 227 2007
2008/0228,051 ANALYTE MEASURING DEVICE 127 2008
2008/0228,054 ANALYTE MEASURING DEVICE 128 2008
2008/0242,961 TRANSCUTANEOUS ANALYTE SENSOR 158 2008
2009/0012,379 SYSTEM AND METHODS FOR PROCESSING ANALYTE SENSOR DATA 200 2008
2008/0306,368 SYSTEM AND METHODS FOR PROCESSING ANALYTE SENSOR DATA 202 2008
2009/0030,294 IMPLANTABLE ANALYTE SENSOR 132 2008
2009/0036,763 ANALYTE SENSOR 129 2008
2009/0045,055 SENSOR HEAD FOR USE WITH IMPLANTABLE DEVICES 165 2008
2009/0247,855 POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS 127 2009
2009/0247,856 POLYMER MEMBRANES FOR CONTINUOUS ANALYTE SENSORS 127 2009
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2010/0204,555 DEVICE AND METHOD FOR DETERMINING ANALYTE LEVELS 44 2010
 
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CHILDREN'S HOSPITAL MEDICAL CENTER (2)
4,680,268 Implantable gas-containing biosensor and method for measuring an analyte such as glucose 308 1985
4,721,677 Implantable gas-containing biosensor and method for measuring an analyte such as glucose 289 1987
 
CIBA VISION CORPORATION (2)
5,070,169 Wettable, flexible, oxygen permeable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units and use thereof 68 1989
5,010,141 Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof 116 1990
 
CINVENTION AG (2)
2006/0177,379 Composition comprising an agent providing a signal, an implant material and a drug 51 2005
2006/0159,718 Method for the production of porous carbon-based molded bodies, and use thereof as cell culture carrier systems and culture systems 12 2006
 
Duquesne University of the Holy Ghost (2)
5,387,327 Implantable non-enzymatic electrochemical glucose sensor 189 1992
5,469,846 Implantable non-enzymatic electrochemical glucose sensor 269 1994
 
E. I. DU PONT DE NEMOURS AND COMPANY (2)
4,267,145 Process for preparing cold water-soluble films from PVA by melt extrusion 15 1978
2007/0129,524 Thermoplastic polyurethanes comprising polytrimethylene ether soft segments 20 2005
 
ELAN CORPORATION, PLC (2)
5,807,375 Analyte-controlled liquid delivery device and analyte monitor 426 1995
5,800,420 Analyte-controlled liquid delivery device and analyte monitor 367 1996
 
GENERAL ELECTRIC COMPANY (2)
2005/0112,358 Methods for deposition of sensor regions onto optical storage media substrates and resulting devices 17 2003
2006/0249,446 Solvent-resistant composite membrane composition 10 2005
 
HEMOTEQ GMBH (2)
2004/0234,575 Medical products comprising a haemocompatible coating, production and use thereof 36 2004
2005/0176,678 Compounds and method for coating surfaces in a haemocompatibe manner 28 2004
 
INTEG, INC. (2)
5,582,184 Interstitial fluid collection and constituent measurement 502 1994
5,820,570 Interstitial fluid collection and constituent measurement 217 1997
 
Miles Laboratories, Inc. (2)
4,415,666 Enzyme electrode membrane 166 1981
4,418,148 Multilayer enzyme electrode membrane 224 1981
 
Minnesota Mining and Manufacturing Company (2)
4,786,657 Polyurethanes and polyurethane/polyureas crosslinked using 2-glyceryl acrylate or 2-glyceryl methacrylate 60 1987
4,952,618 Hydrocolloid/adhesive composition 63 1988
 
MITSUBISHI RAYON CO., LTD. (2)
4,442,841 Electrode for living bodies 126 1981
4,672,970 Electrode for living body 95 1985
 
NEC CORPORATION (2)
5,384,028 Biosensor with a data memory 250 1993
6,144,871 Current detecting sensor and method of fabricating the same 88 1999
 
NOVO NORDISK A/S (2)
5,269,891 Method and apparatus for determination of a constituent in a fluid 260 1993
2004/0063,167 Minimising calibration problems of in vivo glucose sensors 26 2003
 
OPTICAL SENSORS INCORPORATED (2)
2003/0225,324 Noninvasive detection of a physiologic Parameter within a body tissue of a patient 27 2002
2004/0006,263 Noninvasive detection of a physiologic parameter within a body tissue of a patient 20 2003
 
PACESETTER, INC. (2)
5,967,986 Endoluminal implant with fluid flow sensing capability 235 1997
6,409,674 Implantable sensor with wireless communication 256 1998
 
Radiometer A/S (2)
5,242,835 Method and apparatus for determining the concentration of oxygen 36 1992
6,051,389 Enzyme sensor 90 1999
 
RADIOMETER MEDICAL APS (2)
2006/0275,857 Enzyme sensor with a cover membrane layer covered by a hydrophilic polymer 21 2006
2006/0275,859 Enzyme sensor including a water-containing spacer layer 18 2006
 
Sensors for Medicine and Science, Inc. (2)
6,330,464 Optical-based sensing devices 284 1999
6,400,974 Implanted sensor processing system and method for processing implanted sensor output 87 2000
 
SIEMENS HEALTHCARE DIAGNOSTICS INC. (2)
5,494,562 Electrochemical sensors 320 1994
5,863,972 Randomly segmented thermoplastic polyurethanes as matrix for electrochemical analysis of Ca.sup.++ ions 18 1997
 
Solutech, Inc. (2)
4,726,381 Dialysis system and method 34 1986
4,763,658 Dialysis system 2nd method 29 1987
 
TEIJIN LIMITED (2)
4,493,714 Ultrathin film, process for production thereof, and use thereof for concentrating a specified gas in a gaseous mixture 39 1983
4,644,046 Ultrathin film, process for production thereof, and use thereof for concentrating a specific gas from a gas mixture 22 1985
 
TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (2)
5,508,509 Sensing elements and methods for uniformly making individual sensing elements 28 1993
5,670,097 Method of making blood gas sensors overcoats using permeable polymeric compositions 25 1994
 
The Procter & Gamble Company (2)
5,955,066 Conditioning shampoo compositions having improved stability 38 1997
5,837,661 Conditioning shampoos containing polyalkylene glycol 49 1997
 
The Research Foundation of State University of New York (2)
4,602,922 Method of making membranes for gas separation and the composite membranes 54 1985
4,954,381 Preparation of porous substrates having well defined morphology 25 1988
 
UNIVERSITY OF PITTSBURGH (2)
4,805,624 Low-potential electrochemical redox sensors 220 1987
6,256,522 Sensors for continuous monitoring of biochemicals and related method 188 1995
 
UNWIRED PLANET, LLC (2)
2001/0001,008 Transmitter/receiver for GMSK and Offset-QAM 1 2000
2001/0001,008 Transmitter/receiver for GMSK and Offset-QAM 1 2000
 
VICTORIA UNIVERSITY OF MANCHESTER, THE (2)
4,886,740 Enzyme-electrode sensor with organosilane treated membrane 55 1986
5,531,878 Sensor devices 348 1995
 
WISCONSIN ALUMNI RESEARCH FOUNDATION (2)
4,880,883 Biocompatible polyurethanes modified with lower alkyl sulfonate and lower alkyl carboxylate 28 1987
5,221,724 Polysiloxane polyurea urethanes 46 1990
 
3M INNOVATIVE PROPERTIES COMPANY (1)
6,407,195 Tackified polydiorganosiloxane oligourea segmented copolymers and a process for making same 48 1997
 
ABBOTT CARDIOVASCULAR SYSTEMS INC. (1)
2009/0004,243 Biodegradable triblock copolymers for implantable devices 12 2007
 
ABBOTT LABORATORIES (1)
6,801,041 Sensor having electrode for determining the rate of flow of a fluid 208 2002
 
ABBOTT POINT OF CARE INC. (1)
6,030,827 Microfabricated aperture-based sensor 172 1998
 
ACCORD PARTNER LIMITED (1)
7,172,075 Defect free composite membranes, method for producing said membranes and use of the same 12 2003
 
AD-TECH MEDICAL INSTRUMENT CORPORATION (1)
4,805,625 Sphenoidal electrode and insertion method 160 1987
 
AKZO N.V. (1)
4,686,044 Polycarbonate-polyether-copolymer membrane 39 1985
 
ALLERGAN, INC. (1)
5,833,603 Implantable biosensing transponder 563 1996
 
ALZA CORPORATION (1)
6,091,975 Minimally invasive detecting device 357 1998
 
AMERICARE DIAGNOSTICS, INC. (1)
5,462,064 Integrated system for biological fluid constituent analysis 144 1994
 
ANGIOTECH BIOCOATINGS CORP. (1)
2007/0299,409 Antimicrobial Needle Coating For Extended Infusion 26 2005
 
Angiotech International AG (1)
2005/0209,665 Electrical devices and anti-scarring agents 32 2004
 
ANGIOTECH PHARMACEUTICALS, INC. (1)
6,358,557 Graft polymerization of substrate surfaces 36 1999
 
ANIMAS CORPORATION (1)
6,049,727 Implantable sensor and system for in vivo measurement and control of fluid constituent levels 387 1998
 
APPLIED MEDICAL RESEARCH, INC. (1)
5,706,807 Sensor device covered with foam membrane 105 1996
 
ASAHI KASEI CHEMICALS CORPORATION (1)
6,569,309 Fuel cell type reactor and method for producing a chemical compound by using the same 67 2001
 
AVID MARKETING, INC. (1)
5,963,132 Encapsulated implantable transponder 145 1996
 
BAAYER CORPORATION (1)
5,429,735 Method of making and amperometric electrodes 163 1994
 
BASF AKTIENGESELLSCHAFT (1)
6,867,262 Grafted polymers as gas hydrate inhibitors 25 2002
 
BAYBANK (1)
5,208,313 Waterproof breathable polyurethane membranes and porous substrates protected therewith 28 1992
 
BAYER CORPORATION (1)
5,653,863 Method for reducing bias in amperometric sensors 338 1996
 
BBC Brown, Boveri & Company, Limited (1)
4,197,840 Permanent magnet device for implantation 132 1976
 
Bio Medic Data Systems, Inc. (1)
5,840,148 Method of assembly of implantable transponder 104 1995
 
BioInterface Technologies, Inc. (1)
5,045,601 Pressure-sensitive adhesive compositions suitable for medical uses 35 1989
 
Biotek, Inc. (1)
4,403,984 System for demand-based adminstration of insulin 246 1980
 
BioTronic Technologies, Inc. (1)
6,670,115 Devices and methods for detecting analytes using electrosensor having capture reagent 63 2000
 
BLERSCH, JUERGEN, DR. (1)
2005/0079,200 Biocompatibly coated medical implants 51 2004
 
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (1)
5,611,900 Microbiosensor used in-situ 189 1995
 
BOC HEALTH CARE, INC. (1)
5,155,149 Silicone polyurethane copolymers containing oxygen sensitive phosphorescent dye compounds 34 1991
 
BODY SCIENCE LLC (1)
5,957,854 Wireless medical diagnosis and monitoring equipment 347 1997
 
Boehringer Mannheim GmbH (1)
5,507,288 Analytical system for monitoring a substance to be analyzed in patient-blood 545 1995
 
BOSTON SCIENTIFIC NEUROMODULATION CORPORATION (1)
6,208,894 System of implantable devices for monitoring and/or affecting body parameters 477 1998
 
BOSTON SCIENTIFIC SCIMED, INC. (1)
6,368,658 Coating medical devices using air suspension 201 2000
 
BRIDGER BIOMED, INC. (1)
5,480,711 Nano-porous PTFE biomaterial 15 1994
 
CALIFORNIA INSTITUTE OF TECHNOLOGY (1)
5,959,191 Sensor arrays for detecting analytes in fluids 53 1998
 
CARDIAC PACEMAKERS, INC. (1)
2003/0036,773 Systems and methods for treatment of coronary artery disease 135 2002
 
CASIO COMPUTER CO., LTD. (1)
5,316,008 Measurement of electrocardiographic wave and sphygmus 201 1991
 
CERCACOR LABORATORIES, INC. (1)
5,743,262 Blood glucose monitoring system 466 1995
 
Chem-Elec, Inc. (1)
5,130,231 Blood plasma test device including a semipermeable membrane made of an expanded hydrophobic material that has been treated with a surfactant 41 1989
 
CIRCE ACQUISITION CORP. (1)
5,834,583 Block copolymers 37 1997
 
CLINICAL DIAGNOSTIC SYSTEMS INC. (1)
4,988,341 Sterilizing dressing device and method for skin puncture 138 1989
 
COMMTECH INTERNATIONAL MANAGEMENT CORPORATION (1)
5,183,549 Multi-analyte sensing electrolytic cell 45 1990
 
CONTINENTAL AUTOMOTIVE GMBH (1)
6,699,383 Method for determining a NOx concentration 77 2002
 
COOPER COMPANIES, INC., THE (1)
4,454,295 Cured cellulose ester, method of curing same, and use thereof 72 1983
 
CORVITA CORPORATION (1)
5,147,725 Method for bonding silicone rubber and polyurethane materials and articles manufactured thereby 66 1990
 
COULTER INTERNATIONAL CORP. (1)
5,607,565 Apparatus for measuring analytes in a fluid sample 91 1995
 
Covalent Partners, LLC (1)
2004/0106,741 Nanofilm compositions with polymeric components 25 2003
 
COVIDIEN LP (1)
2007/0200,267 Pressurized dip coating system 17 2007
 
Criticare Systems, Inc. (1)
6,406,426 Medical monitoring and alert system for use with therapeutic devices 160 1999
 
DANFOSS A/S (1)
2005/0154,272 Method and device for monitoring analyte concentration by use of differential osmotic pressure measurement 21 2005
 
DATA SCIENCES INTERNATIONAL, INC. (1)
6,296,615 Catheter with physiological sensor 54 1999
 
DATEX-OHMEDA, INC. (1)
5,249,576 Universal pulse oximeter probe 251 1991
 
DECOM, INC. (1)
2005/0090,607 Silicone composition for biocompatible membrane 267 2003
 
Derma-Lock Medical Corporation (1)
4,960,594 Polyurethane foam dressing 25 1988
 
DESERET MEDICAL, INC., A CORP. OF DE. (1)
4,647,643 Soft non-blocking polyurethanes 50 1985
 
DexCorn, Inc. (1)
2009/0062,633 IMPLANTABLE ANALYTE SENSOR 142 2008
 
DOW CORNING LIMITED (1)
5,169,906 Film-forming copolymers and their use in water vapor permeable coatings 16 1991
 
E. FRESENIUS CHEMISCH PHARMAZEUTISCHE INDUSTRIE KG APPARATEBAU KG (1)
4,256,561 Electrochemical measuring electrode 16 1979
 
ECOSSENSORS LIMITED (1)
5,575,930 Method of making gas permeable membranes for amperometric gas electrodes 148 1995
 
EDT PHARMA HOLDINGS (1)
6,275,717 Device and method of calibrating and testing a sensor for in vivo measurement of an analyte 356 1998
 
EDWARDS LIFESCIENCES CORPORATION (1)
2007/0202,562 Flux limiting membrane for intravenous amperometric biosensor 13 2007
 
EGOMEDICAL SWISS AG (1)
2005/0196,747 Analyte test system for determining the concentration of an analyte in a physiological or aqueous fluid 16 2005
 
ELAN PHARMA INTERNATIONAL LIMITED (1)
5,820,622 Analyte-controlled liquid delivery device and analyte monitor 267 1996
 
EM MICROELECTRONIC-MARIN SA (1)
5,895,235 Process for manufacturing transponders of small dimensions 83 1997
 
Encelle, Inc. (1)
5,776,324 Electrochemical biosensors 96 1996
 
ENDONETICS, INC. (1)
2004/0158,138 Implantable monitoring probe 30 2003
 
Evreka, Inc. (1)
4,436,094 Monitor for continuous in vivo measurement of glucose concentration 291 1982
 
Firma Carl Freudenberg (1)
4,973,320 Tissue-compatible medical device and method for manufacturing the same 63 1988
 
FIRST NATIONAL BANK OF BOSTON, THE (1)
4,759,828 Glucose electrode and method of determining glucose 324 1987
 
FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH (1)
2005/0274,665 Capillary membrane and device for production thereof 10 2004
 
FUJIFILM CORPORATION (1)
2008/0081,184 BIOCHEMICAL INSTRUMENT 11 2007
 
FUJITSU LIMITED (1)
5,589,133 Oxygen electrode, biosensor and processes for manufacturing same 62 1994
 
GATES ENERGY PRODUCTS, INC. (1)
4,255,500 Vibration resistant electrochemical cell having deformed casing and method of making same 134 1979
 
GENENCOR INTERNATIONAL, INC. (1)
5,578,463 Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same 34 1994
 
GINER, INC. (1)
5,944,661 Potential and diffusion controlled solid electrolyte sensor for continuous measurement of very low levels of transdermal alcohol 135 1997
 
GIVEN IMAGING LTD. (1)
6,285,897 Remote physiological monitoring system 205 1999
 
GOLDSCHMIDT AG (1)
4,861,830 Polymer systems suitable for blood-contacting surfaces of a biomedical device, and methods for forming 99 1987
 
Goldstar Co., Ltd. (1)
5,571,395 Breath alcohol analyzer using a biosensor 128 1994
 
GORE HYBRID TECHNOLOGIES, INC. (1)
5,914,182 Materials and methods for the immobilization of bioactive species onto polymeric substrates 116 1996
 
GREATBATCH LTD. (1)
6,013,113 Slotted insulator for unsealed electrode edges in electrochemical cells 116 1998
 
HEMOTEQ AG (1)
2008/0038,307 Biocompatible Coating, Method, and Use of Medical Surfaces 23 2005
 
HER MAJESTY IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF COMMUNICATIONS (1)
5,321,414 Dual polarization dipole array antenna 28 1993
 
HOFFMANN-LA ROCHE INC. (1)
5,931,814 Dermally affixed injection device 220 1997
 
HOSPIRA, INC. (1)
5,310,469 Biosensor with a membrane containing biologically active material 183 1991
 
HUMANAUTOCELL GMBH (1)
2007/0166,343 Matrix, cell implantation and method for their production and use 10 2004
 
Hydromer, Inc. (1)
7,008,979 Coating composition for multiple hydrophilic applications 60 2002
 
IMPERIAL COLLEGE OF SCIENCE AND MEDICINE (1)
5,462,645 Dialysis electrode device 169 1994
 
INFOPIA CO., LTD. (1)
6,554,982 Miniaturized solid-state reference electrode with self-diagnostic function 11 2001
 
INNERDYNE, INC. (1)
5,342,693 Multifunctional thrombo-resistant coating and methods of manufacture 49 1993
 
INSTITUT FRANCAIS DU PETROLE (1)
5,071,452 Gas separation membrane 27 1990
 
INSTITUT FUER DIABETES-TECHNOLOGIE GEMEINNUETZIGE FORSCHUNGS-UND ENTWICKLUNGSGESELLSCHAFT MBH AN DER UNIVERSITAET ULM (1)
5,640,954 Method and apparatus for continuously monitoring the concentration of a metabolyte 201 1995
 
INSTITUT PASTEUR (1)
5,906,817 Biocompatible implant for the expression and in vivo secretion of a therapeutic substance 44 1996
 
Institute fur Diabetestechnologie Gemeinnutzige Forschungs- und Entwicklungsgesellschaft mbH (1)
4,919,141 Implantable electrochemical sensor 291 1988
 
INSTRUMENTATION LABORATORY COMPANY (1)
2005/0233,407 Cross-linked enzyme matrix and uses thereof 12 2005
 
INTEGUMENT TECHNOLOGIES, INC. (1)
5,977,241 Polymer and inorganic-organic hybrid composites and methods for making same 52 1997
 
INTELLECTUAL DISCOVERY CO., LTD. (1)
6,969,451 Fluid-type multiple electrochemical system and preparation thereof 85 2002
 
INTERATED IONICS, INC. (1)
4,739,380 Integrated ambient sensing devices and methods of manufacture 43 1984
 
J&J Vision Care, Inc. (1)
7,052,131 Biomedical devices containing internal wetting agents 41 2002
 
JAPAN TOBACCO INC. (1)
5,947,127 Tobacco filters and method of producing the same 16 1997
 
JOSLIN DIABETES CENTER, INC. (1)
4,340,458 Glucose sensor 168 1980
 
KOCH MEMBRANE SYSTEMS, INC. (1)
4,527,999 Separation membrane and method of preparing and using same 40 1984
 
KT HOLDINGS, LLC (1)
5,932,299 Method for modifying the surface of an object 254 1997
 
KUDD, ARTHUR R. (1)
4,787,398 Glucose medical monitoring system 384 1986
 
Kyoto Daiichi Kagaku Co., Ltd. (1)
5,397,451 Current-detecting type dry-operative ion-selective electrode 17 1994
 
LEASE ENGINEERING PTY. LTD. (1)
4,482,666 Emulsions of liquid hydrocarbons with water and/or alcohols 13 1983
 
LEGACY EMANUEL HOSPITAL & HEALTH CENTER (1)
2008/0027,301 Analyte sensing and response system 19 2006
 
LEYBOLD INFICON (1)
5,703,359 Composite membrane and support assembly 29 1996
 
LG CHEM, LTD. (1)
7,014,948 Electrochemical device using multicomponent composite membrane film 11 2002
 
LG CHEMICAL CO., LTD. (1)
7,470,488 Multi-component composite film method for preparing the same 10 2001
 
LIFESCAN SCOTLAND LIMITED (1)
2005/0139,489 Method of reducing the effect of direct and mediated interference current in an electrochemical test strip 141 2004
 
LOCKHEED MARTIN CORPORATION (1)
4,253,469 Implantable temperature probe 170 1979
 
LOCTITE CORPORATION (1)
4,684,538 Polysiloxane urethane compounds and adhesive compositions, and method of making and using the same 75 1986
 
M-BIOTECH, INC. (1)
6,268,161 Biosensor 244 1999
 
MAQUET CARDIOVASCULAR LLC (1)
5,282,848 Self-supporting woven vascular graft 224 1993
 
MARINE BIOLOGICAL LABORATORY (1)
6,802,957 Self-referencing enzyme-based microsensor and method of use 203 2001
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
6,007,845 Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers 137 1996
 
MEDEX, INC. (1)
5,417,395 Modular interconnecting component support plate 41 1993
 
Meso Scale Technology, Inc. (1)
6,066,448 Multi-array, multi-specific electrochemiluminescence testing 188 1996
 
METROHM AG (1)
5,686,829 Voltammetric method and apparatus 178 1995
 
MINIMED INC., A DELAWARE CORPORATION, D/B/A MINIMED TECHNOLOGIES (1)
5,390,671 Transcutaneous sensor insertion set 489 1994
 
MITSUBISHI GAS CHEMICAL COMPANY, INC. (1)
2009/0012,205 TRANSPARENT GEL AND CONTACT LENSE FROM THE SAME 9 2006
 
MOLECULAR DESIGN INC. (1)
5,837,728 9-cis retinoic acid esters and amides and uses thereof 105 1995
 
MOLTECH POWER SYSTEMS, INC. (1)
6,300,002 Notched electrode and method of making same 122 1999
 
N.V. NEDERLANDSCHE APPARATENFABRIEK NEDAP (1)
5,372,133 Implantable biomedical sensor device, suitable in particular for measuring the concentration of glucose 350 1993
 
National Draeger Incorporated (1)
RE31916 Electrochemical detection cell 130 1981
 
NATIONAL RESEARCH COUNCIL OF CANADA (1)
5,411,866 Method and system for determining bioactive substances 146 1993
 
NEUROGESX, INC. (1)
5,589,498 Transdermal delivery of the active enantiomer of ketorolac 12 1995
 
NIHON KOHDEN CORPORATION (1)
4,273,636 Selective chemical sensitive field effect transistor transducers 35 1978
 
NIPPON PAPER INDUSTRIES CO., LTD. (1)
6,303,670 Cellulose based coating composition curable with ultraviolet ray 19 2000
 
NISHITOMO CO., LTD. (1)
5,137,028 Clinical thermometer for women 187 1990
 
NISSAN MOTOR CO., LTD. (1)
5,034,112 Device for measuring concentration of nitrogen oxide in combustion gas 159 1989
 
NITINOL DEVELOPMENT CORPORATION (1)
2007/0123,963 Method for producing flexible, stretchable, and implantable high-density microelectrode arrays 13 2005
 
NKK Corporation (1)
6,018,013 Coating composition and method for producing precoated steel sheets 12 1998
 
NORTH-STAR RESEARCH INSTITUTE, LTD., A CORP. OF DE (1)
4,890,621 Continuous glucose monitoring and a system utilized therefor 256 1988
 
NOVA BIOMEDICAL CORPORATION (1)
5,352,348 Method of using enzyme electrode 194 1992
 
NOVEMBER AKTIENGESELLSCHAFT GESELLSCHAFT FUR MOLEKULARE MEDIZIN (1)
7,169,289 Electrochemical detection method and device 166 2005
 
OMRON HEALTHCARE CO., LTD. (1)
5,462,051 Medical communication system 318 1994
 
OSMETECH TECHNOLOGY INC. (1)
6,264,825 Binding acceleration techniques for the detection of analytes 202 1999
 
P&V CONSULTING GMBH & CO. KG (1)
7,248,906 Method and device for monitoring analyte concentration by optical detection 21 2002
 
PHARMACONTROL CORPORATION (1)
4,750,496 Method and apparatus for measuring blood glucose concentration 216 1987
 
PICHA, GEORGE J. (1)
5,564,439 Infusion device for soft tissue 123 1994
 
POLYTECHNIC UNIVERSITY (1)
5,089,112 Electrochemical biosensor based on immobilized enzymes and redox polymers 339 1990
 
POREX CORPORATION (1)
2003/0134,100 Discrete hydrophilic-hydrophobic porous materials and methods for making the same 18 2002
 
POWERZYME, INC. (1)
2003/0228,681 Analyte sensor 53 2003
 
PPG INDUSTRIES OHIO, INC. (1)
5,760,155 Polysiloxane polyurethane compositions 34 1997
 
PRECISION CONTROL DESIGN, INC. (1)
6,366,794 Generic integrated implantable potentiostat telemetry unit for electrochemical sensors 209 1999
 
PURDUE RESEARCH FOUNDATION (1)
6,018,033 Hydrophilic, hydrophobic, and thermoreversible saccharide gels and forms, and methods for producing same 39 1997
 
Quiclave, L.L.C. (1)
5,552,112 Method and system for sterilizing medical instruments 31 1995
 
RADIOMETER CALIFORNIA, INC. (1)
6,022,463 Sensors with subminiature through holes 20 1996
 
REGENTS OF THE UNIVERSITY OF MINNESOTA (1)
4,927,407 Cardiac assist pump with steady rate supply of fluid lubricant 163 1989
 
Research Foundation, The City University of New York (1)
4,883,057 Cathodic electrochemical current arrangement with telemetric application 125 1986
 
RIKEN (1)
6,773,565 NOx sensor 88 2001
 
ROBERT BOSCH GMBH (1)
6,325,979 Device for gas-sensoring electrodes 119 1999
 
ROCHE DIAGNOSTICS INTERNATIONAL AG (1)
7,335,286 Immersion sensor for measuring the concentration of an analyte with the help of an oxidase 18 2003
 
SAADAT, VAHID (1)
6,991,643 Multi-barbed device for retaining tissue in apposition and methods of use 123 2000
 
SAMSUNG SDI CO., LTD. (1)
2006/0263,673 Cylindrical lithium secondary battery 13 2006
 
SAN MEDITECH (HUZHOU) CO., LTD (1)
2008/0033,269 Catheter-free implantable needle biosensor 20 2005
 
SANKYO COMPANY, LIMITED (1)
4,871,440 Biosensor 272 1988
 
SCIMED LIFE SYSTEMS, INC. (1)
2006/0171,980 Implantable or insertable medical devices having optimal surface energy 31 2005
 
SEGARS CALIFORNIA PARTNERS, LP (1)
5,804,048 Electrode assembly for assaying glucose 186 1996
 
SENDX MEDICAL, INC. (1)
2006/0065,527 Polymeric reference electrode 10 2004
 
SENSALYSE HOLDINGS LIMITED (1)
6,200,772 Modified polyurethane membrane sensors and analytical methods 82 2000
 
SHARP KABUSHIKI KAISHA (1)
5,331,555 Electronic apparatus 192 1991
 
SHIN-ETSU CHEMICAL CO., LTD. (1)
4,803,243 Block-graft copolymer 99 1987
 
SKC CO., LTD. (1)
6,547,839 Method of making an electrochemical cell by the application of polysiloxane onto at least one of the cell components 116 2001
 
SMITH INTERNATIONAL, INC. (1)
6,789,634 Self-lubricating elastomeric seal with polarized graphite 18 2003
 
SORENSON DEVELOPMENT, INCORPORATED (1)
6,965,791 Implantable biosensor system, apparatus and method 195 2003
 
ST. JUDE MEDICAL, INC. (1)
4,795,542 Electrochemical concentration detector device 82 1986
 
STICHTING DUTCH POLYMER INSTITUTE (1)
2006/0293,487 POLYURETHANES, POLYURETHANEUREAS AND POLYUREAS AND USE THEREOF 18 2006
 
SUDORMED, INC. (1)
5,438,984 Apparatus and method for the collection of analytes on a dermal patch 82 1993
 
Sunshine Medical Instruments, Inc. (1)
5,448,992 Method and apparatus for non-invasive phase sensitive measurement of blood glucose concentration 134 1993
 
SYNTHEON, LLC (1)
6,066,083 Implantable brachytherapy device having at least partial deactivation capability 76 1998
 
TECHNICON INSTRUMENTS CORPORATION (1)
4,225,410 Integrated array of electrochemical sensors 305 1978
 
TERUMO KABUSHIKI KAISHA (1)
4,689,149 Device for transfer of medical substance 24 1984
 
TEXAS INSTRUMENTS INCORPORATED (1)
4,992,794 Transponder and method for the production thereof 148 1989
 
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (1)
6,074,775 Battery having a built-in controller 74 1998
 
The Goodyear Tire & Rubber Company (1)
6,534,711 Encapsulation package and method of packaging an electronic circuit module 97 2000
 
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (1)
4,353,888 Encapsulation of live animal cells 248 1980
 
The Johns Hopkins University (1)
4,494,950 Plural module medication delivery system 506 1982
 
The Penn State Research Foundation (1)
2007/0259,217 Materials and configurations for scalable microbial fuel cells 83 2007
 
The University of Akron (1)
6,528,584 Multi-component polymeric networks containing poly(ethylene glycol) 75 2001
 
THE UNIVERSITY OF BRITISH COLUMBIA (1)
5,624,537 Biosensor and interface membrane 294 1994
 
The University of North Carolina at Chapel Hill (1)
2007/0275,193 Functional Materials and Novel Methods for the Fabrication of Microfluidic Devices 30 2005
 
THERMOMETRICS, INC. (1)
4,554,927 Pressure and temperature sensor 205 1983
 
TORAY INDUSTRIES, INC. (1)
4,632,968 Contact lens and process for preparation thereof 33 1985
 
TRUSTEES OF TUFTS COLLEGE (1)
7,115,884 Self-encoding fiber optic sensor 96 1997
 
TYSON BIORESEARCH, INC. (1)
6,793,802 Biosensors having improved sample application and measuring properties and uses thereof 161 2001
 
U.S. Philips Corporation (1)
4,324,257 Device for the transcutaneous measurement of the partial oxygen pressure in blood 81 1980
 
UNIVERSITY OF CONNECTICUT (1)
6,497,729 Implant coating for control of tissue/implant interactions 126 1999
 
UNIVERSITY OF KANSAS (1)
5,165,407 Implantable glucose sensor 460 1991
 
UNIVERSITY OF SOUTH FLORIDA (1)
2006/0289,307 Epoxy Enhanced Polymer Membrane to Increase Durability of Biosensors 21 2005
 
UNIVERSITY, THOMAS JEFFERSON, A PA CORP. (1)
6,122,536 Implantable sensor and system for measurement and control of blood constituent levels 439 1998
 
UOP LLC (1)
2008/0143,014 Asymmetric Gas Separation Membranes with Superior Capabilities for Gas Separation 10 2006
 
VALERITAS LLC (1)
7,344,499 Microneedle device for extraction and sensing of bodily fluids 121 1999
 
VTQ IP HOLDING CORPORATION (1)
2003/0181,794 Implantable sensor housing, sensor unit and methods for forming and using the same 100 2003
 
WACKER-CHEMIE GMBH (1)
4,292,423 Process for the preparation of organopolysiloxanes 17 1980
 
WHATMAN, INC. (1)
6,071,406 Hydrophilic polymeric phase inversion membrane 63 1999
 
WILLIAM REBER, L.L.C. (1)
5,961,451 Noninvasive apparatus having a retaining member to retain a removable biosensor 297 1997
 
Wing Labo Co., Ltd. (1)
5,582,497 Automatic warehouse system 40 1994
 
World Trade Corporation (1)
5,296,144 Composite membrane of a hydrophilic asymmetric membrane coated with an organosiloxane block copolymer 27 1992
 
YACYNYCH, ALEXANDER M. (1)
5,286,364 Surface-modified electochemical biosensor 277 1991
 
Other [Check patent profile for assignment information] (39)
4,374,013 Oxygen stabilized enzyme electrode 169 1981
4,431,004 Implantable glucose sensor 431 1981
4,685,463 Device for continuous in vivo measurement of blood glucose concentrations 264 1986
4,832,034 Method and apparatus for withdrawing, collecting and biosensing chemical constituents from complex fluids 162 1987
4,823,808 Method for control of obesity, overweight and eating disorders 105 1987
4,902,294 Implantable mammary prosthesis adapted to combat the formation of a retractile shell 55 1987
4,852,573 Implantable neural electrode 207 1987
4,822,336 Blood glucose level sensing 49 1988
4,909,908 Electrochemical cncentration detector method 171 1988
4,953,552 Blood glucose monitoring system 609 1989
5,050,612 Device for computer-assisted monitoring of the body 507 1989
5,464,013 Medical scanning and treatment system and method 46 1991
5,337,747 Implantable device for estimating glucose levels 299 1993
5,508,030 Creating new capillary blood pools for practicing bidirectional medicine 11 1993
5,482,008 Electronic animal identification system 121 1994
5,458,631 Implantable catheter with electrical pulse nerve stimulators and drug delivery system 140 1994
5,795,453 Electrodes and metallo isoindole ringed compounds 57 1996
6,442,413 Implantable sensor 266 2000
6,579,498 Implantable blood glucose sensor system 181 2000
7,033,322 Implantable sensor 118 2001
2002/0042,561 Implantable sensor and integrity tests therefor 181 2001
6,895,265 Implantable sensor 232 2002
2003/0138,674 Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration 68 2002
2003/0157,409 Polymer lithium battery with ionic electrolyte 11 2003
7,118,667 Biosensors having improved sample application and uses thereof 117 2004
2005/0077,584 Hermetically sealed microchip reservoir devices 103 2004
2005/0182,451 Implantable device with improved radio frequency capabilities 116 2005
2005/0197,554 Composite thin-film glucose sensor 23 2005
2005/0271,546 Subcutaneous analyte sensor 90 2005
2006/0079,740 Sensors for detecting substances indicative of stroke, ischemia, or myocardial infarction 53 2005
2006/0257,995 Analyte sensing biointerface 14 2006
2006/0249,447 Solvent-resistant composite membrane composition 10 2006
2007/0059,196 Analyte sensor 16 2006
2007/0038,044 Analyte sensor 80 2006
2007/0166,364 Transdermal Therapeutic System 11 2007
2008/0113,207 Coatings For Drug Delivery Devices Having Gradient Of Hydration 12 2008
2008/0138,497 Methods For Fabricating Coatings For Drug Delivery Devices Having Gradient Of Hydration 13 2008
2008/0138,498 Methods For Fabricating Coatings For Drug Delivery Devices Having Gradient Of Hydration 12 2008
8,196,626 Tire with asymmetric tread profile 9 2009

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
ABBOTT DIABETES CARE INC. (10)
8,123,686 Method and apparatus for providing rolling data in communication systems 0 2007
8,140,142 Method and apparatus for providing data processing and control in medical communication system 0 2008
8,461,985 Analyte monitoring system and methods 0 2008
8,456,301 Analyte monitoring system and methods 0 2008
8,444,560 Method and apparatus for providing data processing and control in a medical communication system 0 2008
8,260,558 Method and apparatus for providing data processing and control in a medical communication system 0 2008
8,239,166 Method and apparatus for providing data processing and control in a medical communication system 0 2008
8,390,455 RF tag on test strips, test strip vials and boxes 0 2009
8,358,210 RF tag on test strips, test strip vials and boxes 0 2009
8,223,021 RF tag on test strips, test strip vials and boxes 1 2009
 
DEXCOM, INC. (2)
8,255,030 Oxygen enhancing membrane systems for implantable devices 0 2006
8,155,723 Device and method for determining analyte levels 0 2010
 
ABBOTT LABORATORIES (1)
8,437,966 Method and system for transferring analyte test data 0 2009

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