Platinum complexes for targeted drug delivery
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United States of America Patent
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Jul 12, 2011
Grant Date -
Aug 27, 2009
app pub date -
Nov 10, 2005
filing date -
Nov 10, 2004
priority date (Note) -
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Abstract
The subject invention concerns biotin-conjugated platinum complexes that exhibit direct and indirect (immunological) antitumor cell activity. The subject invention also concerns the biotin-platinum complexes of the invention that have another molecule, such as an antibody, a ligand, a receptor, etc., bound to the biotin moiety. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the invention can also be used to treat or prevent infection by a virus or a bacterial or parasitic organism in vivo or in vitro.
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