Bicyclonucleoside analogues
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United States of America Patent
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Aug 9, 2011
Grant Date -
Nov 22, 2007
app pub date -
Jan 31, 2007
filing date -
Jul 22, 1999
priority date (Note) -
Expired
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Abstract
Oligonucleotide analogues which have anti-sense or anti-gene activity, as well as in vivo stability, or pharmaceutically acceptable salts thereof. The oligonucleotide analogues have one or more structural units represented by the following formula (1a):provided that when the oligonucleotide has two or more structural units of formula (1a), each B is the same or different, wherein B represents a purin-9-yl group or a 2-oxo-1,2-dihydropyrimidin-1-yl group.
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