Biologically active polypeptides derived from a novel early stage pregnancy factor designated maternin (MA)

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United States of America Patent

PATENT NO 7994278
SERIAL NO

09632831

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to therapeutic polypeptides isolated from beta-human chorionic gonadotropin (β-hCG) found in human early pregnancy urine, now synthetically produced and designated Maternin. The therapeutic polypeptides and their functional equivalents are useful in treating and/or preventing various medical conditions. Examples of therapeutic effects of the therapeutic polypeptides include anti-HIV, anti-cancer, anti-wasting, prohematopoietic (e.g., anemias, radiation-mediated bone marrow damage, and trauma-mediated blood loss), and anti-angiogenic effects. The invention also provides pharmaceutical compositions comprising the therapeutic polypeptides, as well as methods for using the therapeutic polypeptides, functional equivalents and/or pharmaceutical compositions in the treatment and/or prevention of such medical conditions.

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Patent Owner(s)

  • EUV LLC;NOBEL BIOSCIENCES LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bryant, Joseph Baltimore, US 15 229
Gallo, Robert C Bethesda, US 63 1041
Lundardi-Iskandar, Yanto Gaithersburg, US 1 0

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