US Patent No: 8,003,122
Number of patents in Portfolio can not be more than 2000
Device for local and/or regional delivery employing liquid formulations of therapeutic agents
Stats
-
Aug 23, 2011
Issued date -
Mar 31, 2008
filing date -
12/059,291
serial no -
In Force
status
Importance
Loading Importance Indicators...
Abstract
Medical devices may be utilized for local and regional therapeutic agent delivery. These therapeutic agents or compounds may reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the prevention of thrombosis. The drugs, agents, and/or compounds may also be utilized to treat specific disorders, including restenosis, vulnerable plaque, and atherosclerosis in type 2 diabetic patients. In regional delivery, liquid formulations may be desirable to increase the efficacy and deliverability of the particular drug. Various materials and coating methodologies may be utilized to maintain the agents or compounds on the medical device until delivered and positioned.
Loading the Abstract Image...
First Claim
Related Publications
Loading Related Publications...
International Classification(s)
- [Classification Symbol]
- [Patents Count]
Cited Art
| Patent Info | (Count) | # Cites | Year |
|---|---|---|---|
|
|
|||
| 5,248,796 Taxol derivatives | 71 | 1992 | |
| 5,300,638 Asymmetric synthesis of taxol side chain | 28 | 1992 | |
| 5,272,171 Phosphonooxy and carbonate derivatives of taxol | 87 | 1992 | |
| 5,254,580 7,8-cyclopropataxanes | 112 | 1993 | |
| 5,294,637 Fluoro taxols | 64 | 1993 | |
| 5,380,751 6,7-modified paclitaxels | 34 | 1993 | |
| 5,412,092 N-substituted 2-azetidinones | 41 | 1993 | |
| 5,395,850 6,7-epoxy paclitaxels | 19 | 1994 | |
|
|
|||
| 6,136,846 Formulation for paclitaxel | 18 | 1999 | |
| 6,319,943 Oral formulation for paclitaxel | 10 | 2000 | |
| 6,538,020 Paclitaxel formulation | 7 | 2001 | |
| 6,509,370 Paclitaxel formulation | 6 | 2002 | |
| 6,828,346 Methods for administration of paclitaxel | 6 | 2003 | |
|
|
|||
| 4,739,762 Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft | 964 | 1986 | |
| 6,425,898 Delivery apparatus for a self-expanding stent | 95 | 1999 | |
| 2005/0272,806 Injectable formulations of taxanes for cad treatment | 31 | 2004 | |
| 2010/0233,236 DRUG COATED EXPANDABLE DEVICES | 3 | 2010 | |
|
|
|||
| 5,229,172 Modification of polymeric surface by graft polymerization | 143 | 1993 | |
| 5,308,641 Biocompatibility of solid surfaces | 89 | 1993 | |
| 5,350,800 Method for improving the biocompatibility of solid surfaces | 76 | 1993 | |
| 5,415,938 Biocompatability of solid surfaces | 63 | 1994 | |
|
|
|||
| 6,458,373 Emulsion vehicle for poorly soluble drugs | 42 | 1998 | |
| 6,667,048 Emulsion vehicle for poorly soluble drugs | 8 | 1999 | |
| 2003/0105,156 Method for administration of a taxane/tocopherol formulation to enhance taxane therapeutic utility | 5 | 2002 | |
| 2003/0087,954 Method of treating bladder carcinoma using a Taxane/Tocopherol formulation | 5 | 2002 | |
|
|
|||
| 5,059,699 Water soluble derivatives of taxol | 112 | 1990 | |
| 5,352,805 Water soluble derivatives of taxol | 14 | 1991 | |
| 5,278,324 Water soluble derivatives of taxol | 49 | 1991 | |
| 5,411,984 Water soluble analogs and prodrugs of taxol | 14 | 1992 | |
|
|
|||
| 5,516,770 Rapamycin formulation for IV injection | 27 | 1994 | |
| 2004/0106,973 Balloon catheter stent delivery system with ridges | 8 | 2003 | |
| 7,060,709 Method of treating hepatic fibrosis | 10 | 2004 | |
| 2005/0222,191 Solution formulations of sirolimus and its analogs for CAD treatment | 21 | 2004 | |
|
|
|||
| 5,837,313 Drug release stent coating process | 558 | 1996 | |
| 6,120,536 Medical devices with long term non-thrombogenic coatings | 458 | 1996 | |
| 6,099,562 Drug coating with topcoat | 451 | 1997 | |
|
|
|||
| 6,241,762 Expandable medical device with ductile hinges | 197 | 1998 | |
| 6,293,967 Expandable medical device with ductile hinges | 96 | 1999 | |
| 6,764,507 Expandable medical device with improved spatial distribution | 66 | 2001 | |
|
|
|||
| 4,624,257 Surgical instrument for performing anastomosis | 183 | 1984 | |
| 4,917,090 Method for performing an anastomosis | 173 | 1988 | |
| 4,917,091 Annular fastening means | 171 | 1989 | |
|
|
|||
| 6,753,006 Paclitaxel-containing formulations | 32 | 2000 | |
| 2003/0187,062 Paclitaxel-based antitumor formulation | 16 | 2003 | |
|
|
|||
| 4,366,819 Anastomotic fitting | 368 | 1980 | |
| 4,368,736 Anastomotic fitting | 420 | 1980 | |
|
|
|||
| 5,350,866 10-desacetoxytaxol derivatives | 69 | 1992 | |
| 5,283,253 Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them | 90 | 1992 | |
|
|
|||
| 6,248,363 Solid carriers for improved delivery of active ingredients in pharmaceutical compositions | 272 | 1999 | |
| 6,451,339 Compositions and methods for improved delivery of hydrophobic agents | 59 | 2001 | |
|
|
|||
| 5,274,137 Intermediates for preparation of taxols | 29 | 1992 | |
| 5,422,364 Water soluble taxol derivatives | 46 | 1993 | |
|
|
|||
| 5,440,056 9-deoxotaxane compounds | 44 | 1994 | |
|
|
|||
| 5,234,447 Side-to-end vascular anastomotic staple apparatus | 382 | 1990 | |
|
|
|||
| 6,515,016 Composition and methods of paclitaxel for treating psoriasis | 25 | 1997 | |
|
|
|||
| 4,814,470 Taxol derivatives, their preparation and pharmaceutical compositions containing them | 221 | 1987 | |
|
|
|||
| 5,279,949 Process for the isolation and purification of taxol and taxanes from Taxus spp | 35 | 1992 | |
|
|
|||
| 5,294,997 Image signal with pilot signal recording apparatus | 42 | 1992 | |
|
|
|||
| 5,339,906 Positon feedback mechanism for an implement | 15 | 1993 | |
|
|
|||
| 6,153,252 Process for coating stents | 560 | 1999 | |
|
|
|||
| 4,733,665 Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft | 1941 | 1985 | |
|
|
|||
| 4,776,337 Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft | 1050 | 1986 | |
|
|
|||
| 5,252,805 Laser beam machining method | 12 | 1992 | |
|
|
|||
| 4,984,060 Semiconductor device wirings with hillocks | 13 | 1989 | |
|
|
|||
| 2005/0186,696 Gas flowmeter and manufacturing method thereof | 2005 | ||
|
|
|||
| 2010/0331,816 RAPAMYCIN COATED EXPANDABLE DEVICES | 10 | 2010 | |
|
|
|||
| 5,202,448 Processes of converting taxanes into baccatin III | 29 | 1992 | |
|
|
|||
| 2003/0204,239 Endovascular stent with a preservative coating | 39 | 2002 | |
|
|
|||
| 4,942,184 Water soluble, antineoplastic derivatives of taxol | 144 | 1988 | |
|
|
|||
| 5,362,831 Polymer-bound paclitaxel derivatives | 86 | 1993 | |
|
|
|||
| 2004/0224,003 Drug formulations for coating medical devices | 36 | 2004 | |
|
|
|||
| 4,857,653 Process for the preparation of taxol and 10-deacetyltaxol | 172 | 1987 | |
|
|
|||
| 5,229,529 Method of producing .alpha.,.beta.-unsaturated ketolactones | 17 | 1992 | |
|
|
|||
| 4,722,906 Binding reagents and methods | 201 | 1982 | |
|
|
|||
| 6,919,370 Pharmaceutical formulations comprising paclitaxel, derivatives, and pharmaceutically acceptable salts thereof | 7 | 2001 | |
|
|
|||
| 5,200,534 Process for the preparation of taxol and 10-deacetyltaxol | 59 | 1992 | |
|
|
|||
| 5,891,845 Drug delivery systems utilizing liquid crystal structures | 19 | 1997 | |
|
|
|||
| 5,924,997 Catheter and method for the thermal mapping of hot spots in vascular lesions of the human body | 118 | 1997 | |
|
|
|||
| 6,245,026 Thermography catheter | 119 | 1999 | |
|
|
|||
| 2004/0167,152 Parenteral formulations | 22 | 2003 | |
|
|
|||
| 4,350,160 Instrument for establishing vascular anastomoses | 281 | 1980 | |
| 2003/0170,287 Drug delivery systems for the prevention and treatment of vascular diseases | 19 | 2003 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 3.5 Year Payment | $1600.00 | $800.00 | $400.00 | Feb 23, 2015 |
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Feb 23, 2019 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Feb 23, 2023 |
| Fee | Large entity fee | small entity fee | micro entity fee |
|---|---|---|---|
| Surcharge - 3.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 7.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |