39-desmethoxy derivatives of rapamycin
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United States of America Patent
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Aug 30, 2011
Grant Date -
Apr 1, 2010
app pub date -
Dec 3, 2009
filing date -
Mar 11, 2005
priority date (Note) -
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Abstract
The present invention relates to 39-desmethoxyrapamycin derivatives and their uses thereof. The present invention provides for the use of these compounds in the treatment of cancer and/or B-cell malignancies, the induction or maintenance of immunosuppression, the treatment of transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation, vascular disease and fibrotic diseases, the stimulation of neuronal regeneration or the treatment of fungal infections.
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