Drug conjugate composition

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United States of America Patent

PATENT NO 8012485
APP PUB NO 20090142361A1
SERIAL NO

12366830

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Abstract

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The invention provides a lyophilized composition comprising a therapeutically effective amount of a conjugate comprising an antibody chemically coupled to a maytansinoid. The invention further provides a method for killing a cell in a human comprising administering to the human the reconstituted composition such that the antibody binds to the surface of the cell and the cytotoxicity of the maytansinoid is activated, whereby the cell is killed.

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Patent Owner(s)

  • IMMUNOGEN, INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Amphlett, Godfrey Cambridge, US 13 356
Fleming, Michael Londonderry, US 46 1252
Zhang, Wei Wayne, US 2319 17837

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