Gastric retention controlled drug delivery system

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United States of America Patent

PATENT NO 8012496
APP PUB NO 20100305208A1
SERIAL NO

12856097

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides a gastric retention controlled drug delivery system comprising: (a) a controlled release core comprising a drug, a highly swellable polymer and a gas generating agent, said core being capable of swelling and achieving floatation rapidly while maintaining its physical integrity in gastrointestinal fluids for prolonged periods, and (b) a rapidly releasing coat composition comprising the same drug as in the core and pharmaceutically acceptable excipients, wherein the coating composition surrounds the core such that the system provides a biphasic release of the drug in gastrointestinal fluids.

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Patent Owner(s)

Patent OwnerAddress
SUN PHARMA ADVANCED RESEARCH COMPANY LTDMUMBAI 400093 MAHARASHTRA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dharmadhikari, Nitin Bhalachandra Mumbai, IN 37 424
Dhavse, Vaishali Vijay Mumbai, IN 7 56
Dudhara, Kamlesh Mohanlal Baroda, IN 5 118

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