US Patent No: 8,012,990
Number of patents in Portfolio can not be more than 2000
Methods of converting a patient's treatment regimen from intravenous administration of an opioid to oral co-administration of morphine and oxycodone using a dosing algorithm to provide analgesia
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Sep 6, 2011
Issued date -
Sep 14, 2010
filing date -
12/881,728
serial no -
In Force
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Abstract
A method of converting a treatment for pain comprising intravenous administration of opioids, to a treatment for pain comprising oral administration of a first dose of an immediate release morphine-oxycodone combination in patients in need of analgesia. The method may comprise (1) determining a four-hour average oral morphine equivalents or determining a net average hourly intravenous dose, and (2) orally administering to the patient a first dose of a morphine-oxycodone combination in a 3:2 ratio by weight every four to six hours. Also, a method of treating pain in patients who had been administered opioids intravenously, comprising using a dosing algorithm to determine the first dose of the immediate release morphine-oxycodone combination.
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First Claim
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 2005/0053,659 Methods and compositions for reducing the risk associated with the administration of opioid analgesics in patients with diagnosed or undiagnosed respiratory illness | 4 | 2003 | |
| 2009/0291,975 DUAL OPIOID PAIN THERAPY | 5 | 2009 | |
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| 2008/0039,463 Methods and Compositions | 5 | 2004 | |
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| 6,310,072 Production of analgesic synergy by co-administration of sub-analgesic doses of a MU opioid agonist and a kappa-2 opioid agonist | 25 | 1997 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
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| 3.5 Year Payment | $1600.00 | $800.00 | $400.00 | Mar 6, 2015 |
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Mar 6, 2019 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Mar 6, 2023 |
| Fee | Large entity fee | small entity fee | micro entity fee |
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| Surcharge - 7.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
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