US Patent No: 8,017,146

Number of patents in Portfolio can not be more than 2000

Transdermal delivery system with two superimposed adhesive layers having different affinities to the active substance comprised

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ALSO PUBLISHED AS: 20050208116
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Abstract

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A device for the transdermal delivery of a pharmacologically active substance has first and second superimposed mutually contacting adhesive layers (2, 3). The first layer (3) is in use brought into contact with the skin. The active substance is dissolved in both layers, the affinity of the first layer for the active substance being between about 1.15 and about 10 times lower than that of the second layer. The percent saturation of the active substance in both the layers is the same and is less than 100%. The first layer has a greater thickness than the second layer. The device is simple and can provide stable delivery over a long period.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
AMARIN TECHNOLOGIES S.A.BUENOS AIRES2

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Scasso, Alejandro Fabio Buenos Aires, AR 3 11
Stefano, Francisco Jose Evaristo Buenos Aires, AR 4 12

Cited Art Landscape

Patent Info (Count) # Cites Year
 
ALZA CORPORATION (6)
4,262,003 Method and therapeutic system for administering scopolamine transdermally 35 1977
4,286,592 Therapeutic system for administering drugs to the skin 186 1980
4,436,741 Method for administering scopolamine transdermally 9 1983
4,938,759 Transdermal delivery device having a rate controlling adhesive 52 1986
5,004,610 Subsaturated nicotine transdermal therapeutic system 51 1990
6,174,545 Drug delivery devices and process of manufacture 1 1999
 
Noven Pharmaceuticals, Inc. (5)
5,474,783 Solubility parameter based drug delivery system and method for altering drug saturation concentration 118 1991
5,656,286 Solubility parameter based drug delivery system and method for altering drug saturation concentration 164 1994
5,958,446 Solubility parameter based drug delivery system and method for altering drug saturation concentration 57 1995
6,235,306 Solubility parameter based drug delivery system and method for altering drug saturation concentration 25 1999
6,221,383 Solubility parameter based drug delivery system and method for altering drug saturation concentration 52 1999
 
LTS LOHMANN THERAPIE-SYSTEME GMBH (2)
5,230,898 Transdermal therapeutic system exhibiting an increased active substance flow and process for the production thereof 41 1990
6,074,665 Transdermal therapeutic system for administering active agents to the human body via the skin 6 1998
 
BOEHRINGER INGELHEIM INTERNATIONAL GMBH (1)
4,201,211 Therapeutic system for administering clonidine transdermally 140 1977
 
Cygnus Corporation (1)
5,006,342 Resilient transdermal drug delivery device 79 1989
 
DONATIELLO, GUY (1)
6,024,976 Solubility parameter based drug delivery system and method for altering drug saturation concentration 81 1997
 
Hercon Laboratories Corporation (1)
5,310,559 Device for controlled release and delivery to mammalian tissue of pharmacologically active agents incorporating a rate controlling member which comprises an alkylene-alkyl acrylate copolymer 36 1992
 
MYLAN TECHNOLOGIES, INC. (1)
5,662,926 Transdermal patch incorporating a polymer film incorporated with an active agent 19 1995
 
ORTHO-MCNEIL PHARMACEUTICAL, INC. (1)
4,906,463 Transdermal drug-delivery composition 74 1988
 
Sanol Schwarz GmbH (1)
4,769,028 Pharmaceutical product, in medical bandage form 34 1986
 
WATSON PHARMACEUTICALS, INC. (1)
2004/0202,704 Transdermal delivery systems and methods 3 2003

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