Fentanyl composition for nasal administration
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United States of America Patent
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Sep 13, 2011
Grant Date -
Feb 19, 2004
app pub date -
Jul 31, 2001
filing date -
Jul 31, 2000
priority date (Note) -
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Abstract
The treatment of acute pain with a sufficient dosage by intranasal administration of fentanyl results in a time to onset of action comparable to intravenous administration and a significantly faster onset of action than nasal titration of fentanyl. The nasal administration of a sufficient amount of fentanyl to obtain pain relief has lower maximum plasma concentrations comparable to intravenous administration and results in lower rates of adverse events like respiratory depression, nausea and vomiting. Compositions for use in the method are also disclosed.
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