Control release of biologically active compounds from multi-armed oligomers
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United States of America Patent
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Sep 27, 2011
Grant Date -
Mar 19, 2009
app pub date -
Sep 3, 2008
filing date -
Sep 4, 2007
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Abstract
The present invention relates to the discovery of biodegradable multi-armed oligomers wherein the end groups of these oligomers have been functionalized with biologically active molecules. The resultant multi-armed oligomers end-functionalized with biologically active molecules have a controllable degradation profile. The hydrolytic degradation of oligomers of the present invention releases the biologically active compound as such with no change in native chemical structure.
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