Antibody modulating the differentiation and function of dendritic cells via binding intercellular adhesion molecule-1 and use thereof
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United States of America Patent
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Sep 27, 2011
Grant Date -
Jul 1, 2010
app pub date -
Mar 24, 2009
filing date -
Aug 8, 2008
priority date (Note) -
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Abstract
The present invention relates to an antibody binding to human intercellular adhesion molecule-1 (ICAM-1) where the antibody is able to modulate the differentiation status of dendritic cells and prolong the graft survival. In addition, the present invention provides a pharmaceutical composition comprising the antibody, and method of using them for the treatment of disease.
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