Method of identifying a target analyte using photonic crystal resonators, and related device

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United States of America Patent

PATENT NO 8029994
APP PUB NO 20100028898A1
SERIAL NO

12534266

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method of identifying target analytes in a sample, particularly a biological sample, comprising the steps of putting a plurality of target analytes, bound to a common luminescent marker, in contact with a plurality of molecular probes immobilized on a support, each of said molecular probes being capable of complementary binding to a respective target analyte, if said target analyte is present in the sample, providing to said support an excitation radiation and detecting an emission radiation coming from said support as a result of at least one complementary binding event, characterized by the fact that: said support comprises a plurality of photonic crystal resonators, at least two of said resonators being characterized by different resonance wavelengths; each of said molecular probes being fixed to a respective resonator; and by the fact that the identification of at least one target analyte is carried out through the analysis of the total emission spectrum coming from said plurality of photonic crystals resonators, in order to detect possible wavelength resonance peaks generated as a result of the binding of said target analyte, bound to the common luminescent marker, to one or more of said molecular probes.

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Patent Owner(s)

  • CONSIGLIO NAZIONALE DELLE RICERCHE;GLOBUS MEDICAL, INC.;CONSIGLIO NAZIONALE DELLE RICERCHE-INFM ISTITUTO NAZION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aoki, Kanna Saitama, JP 4 11
Arakawa, Yasuhiko Kawasaki, JP 44 228
Cingolani, Roberto Lecce, IT 28 78
De, Vittorio Massimo Lecce, IT 9 59
Martiradonna, Luigi Bari, IT 2 11
Massaro, Alessandro Ancona, IT 2 9
Pisanello, Ferruccio Paris, FR 3 12
Pompa, Pier Paolo Lecce, IT 17 15
Rinaldi, Rosaria Lecce, IT 2 4
Sabella, Stefania Galatina, IT 4 4
Stomeo, Tiziana Martano, IT 1 3

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