Methods of optimizing drug therapeutic efficacy for treatment of immune-mediated gastrointestinal disorders
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United States of America Patent
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Oct 4, 2011
Grant Date -
Feb 4, 2010
app pub date -
Aug 4, 2009
filing date -
Sep 24, 1998
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Abstract
The present invention provides a method of optimizing therapeutic efficacy and reducing toxicity associated with 6-mercaptopurine drug treatment of an immune-mediated gastrointestinal disorder such as inflammatory bowel disease. The method of the invention includes the step of determining the level of one or more 6-mercaptopurine metabolites in the patient having an immune-mediated gastrointestinal disorder.
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