Methods for molecular detection
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United States of America Patent
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Oct 11, 2011
Grant Date -
Jan 7, 2010
app pub date -
Jun 6, 2009
filing date -
Jun 6, 2008
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Abstract
This invention relates to methods for molecular detection, particularly to methods utilizing target-specific molecular probes. In exemplary embodiments, target-specific molecular probes include single-stranded deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) aptamers. In general, the molecular probe may bind with relatively high specificity to a given target. In one aspect, a method for molecular detection comprises a molecular probe paired to a reporter molecule wherein the molecular probe impairs the amplification of the reporter molecule in the absence of the target molecule.
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