US Patent No: 8,036,729 - Analytics, PDF, Full Text and PAIR Access

Number of patents in Portfolio can not be more than 2000

Assessing the condition of a joint and devising treatment

ALSO PUBLISHED AS: 20040167390
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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods are disclosed for assessing the condition of a cartilage in a joint, particularly a human knee. The methods include converting an image such as an MRI to a three dimensional map of the cartilage. The cartilage map can be correlated to a movement pattern of the joint to assess the affect of movement on cartilage wear. Changes in the thickness of cartilage over time can be determined so that therapies can be provided. Information on thickness of cartilage and curvature of cartilage or subchondral bone can be used to plan therapy. Information on movement pattern can be used to plan therapy.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYPALO ALTO, CA2063

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lang, Philipp Lexington, MA 336 14048
Steines, Daniel Palo Alto, CA 250 11350

Cited Art Landscape

Patent Info (Count) # Cites Year
 
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6,106,529 Epicondylar axis referencing drill guide 150 1998
 
GROUPE CONTROLE DEDIENNE GDC SOCIETE DE DROIT FRANCAIS (1)
6,203,576 Complete knee joint prosthesis 152 1999
 
SIEMENS AKTIENGESELLSCHAFT (3)
* 6,334,066 Method for monitoring growth disorder therapy 38 1999
* 6,311,083 Method for determining an examination point for the diaphanoscopic examination of a being and device for realizing the same 8 2000
6,556,855 Method for the implementation of a perfusion measurement with magnetic resonance imaging 39 2001
 
CORNELL UNIVERSITY (1)
* 5,913,821 Diagnostic method and apparatus for assessing canine hip dysplasia 40 1997
 
GENZYME CORPORATION (4)
* 5,723,331 Methods and compositions for the repair of articular cartilage defects in mammals 214 1995
5,900,245 Compliant tissue sealants 210 1996
* 5,786,217 Methods and compositions for the repair of articular cartilage defects in mammals 248 1997
6,217,894 Compliant tissue sealants 164 2000
 
WHALEDENT INC. (1)
4,368,040 Dental impression tray for forming a dental prosthesis in situ 109 1981
 
Fonar Corporation (3)
* 5,810,006 Multipositional MRI for kinematic studies of movable joints 55 1995
* 5,899,859 Multipositional MRI for kinematic studies of movable joints 94 1995
* 5,772,595 Multipositional MRI for kinematic studies of movable joints 50 1996
 
Artecal, Sciences, Inc. (1)
6,841,150 Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair 50 2002
 
OSIRIS THERAPEUTICS, INC. (1)
* 6,835,377 Osteoarthritis cartilage regeneration 137 1998
 
AESCULAP (1)
6,387,131 Knee prosthesis comprising a tibial wedge 84 2000
 
MUSCULOGRAPHICS, INC. (1)
* 5,682,886 Computer-assisted surgical system 583 1995
 
MICROPORT ORTHOPEDICS HOLDINGS INC. (5)
6,013,103 Medial pivot knee prosthesis 247 1997
6,156,069 Precision hip joint replacement method 181 1999
7,060,074 Instrumentation for minimally invasive unicompartmental knee replacement 146 2002
7,141,053 Methods of minimally invasive unicompartmental knee replacement 158 2002
2006/0235,421 Instrumentation for Minimally Invasive Unicompartmental Knee Replacement 94 2006
 
SMITH & NEPHEW ORTHOPAEDICS AG (1)
6,165,221 Implant 44 1999
 
Joint Medical Products Corporation (1)
4,888,021 Knee and patellar prosthesis 164 1988
 
METALPRAECIS BERCHEM + SCHABERG GESELLSCHAFT FUR METALLFORMGEBUNG MBH (1)
* 5,150,304 Method of making an implantable joint prosthesis 110 1990
 
SULZER MEDIZINALTECHNIK AG (1)
5,501,687 Body for distributing bone cement for the anchoring of implants 107 1993
 
Artecel Sciences, Inc. (1)
6,429,013 Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair 131 2000
 
SMITH & NEPHEW, INC. (7)
4,673,409 Implant with attachment surface 91 1986
5,478,739 Three-dimensional stromal cell and tissue culture system 122 1992
5,842,477 Method for repairing cartilage 375 1996
5,928,945 Application of shear flow stress to chondrocytes or chondrocyte stem cells to produce cartilage 87 1996
6,120,541 Apparatus for use in grafting articular cartilage 77 1999
6,375,658 Cartilage grafting 144 2000
6,358,253 Repairing cartilage 141 2000
 
RadioMed Corporation (2)
8,320,995 Fiducial marker with rings 6 2007
8,320,995 Fiducial marker with rings 6 2007
 
Human Performance Technologies, Inc. (1)
4,813,436 Motion analysis system employing various operating modes 108 1987
 
ABS CORPORATION (6)
6,626,945 Cartilage repair plug 139 2001
2001/0039,455 Cartilage repair plug 145 2001
6,652,587 Method and system for mammalian joint resurfacing 203 2002
2002/0173,852 Method and system for mammalian joint resurfacing 103 2002
2006/0111,726 Method and kit for interpositional arthroplasty 72 2003
2007/0067,032 Meniscus preserving implant method and apparatus 86 2004
 
MITSUBISHI DENKI KABUSHIKI KAISHA (2)
6,151,521 Medical support system 49 1998
6,334,006 Loading device and electronic equipment system 37 1998
 
NORTH SHORE UNIVERSITY HOSPITAL RESEARCH CORPORATION (1)
5,769,899 Cartilage repair unit 358 1996
 
SMITH & NEPHEW RICHARDS INC. (5)
5,108,452 Modular hip prosthesis 197 1990
5,560,096 Method of manufacturing femoral knee implant 81 1995
5,575,793 Patella clamp apparatus 84 1995
5,683,470 Tibial trial prosthesis and bone preparation system 35 1995
5,702,463 Tibial prosthesis with polymeric liner and liner insertion/removal instrument 95 1996
 
ORTHOPHOENIX, LLC (1)
5,827,289 Inflatable device for use in surgical protocols relating to treatment of fractured or diseased bones 403 1996
 
W. L. GORE & ASSOCIATES, INC. (1)
6,328,765 Methods and articles for regenerating living tissue 229 1998
 
Vertegen, Inc. (2)
2007/0083,266 Devices and methods for treating facet joints, uncovertebral joints, costovertebral joints and other joints 128 2006
2007/0118,222 Intervertebral devices and methods 55 2006
 
MEDICAL CENTER OF CENTRAL GEORGIA, THE (1)
5,906,934 Mesenchymal stem cells for cartilage repair 258 1995
 
HEIMANN SYSTEMS (1)
5,687,210 Method and device for determining the attenuation function of an object with respect to the transmission of a reference material thickness 130 1996
 
INAMED MEDICAL PRODUCTS CORPORATION (1)
5,480,430 Shape-retaining shell for a fluid filled prosthesis 61 1994
 
Orthogene LLC (1)
2002/0016,543 Method for diagnosis of and prognosis for damaged tissue 40 2001
 
Huwmedica Inc. (1)
5,542,947 Slotted patella resection guide and stylus 135 1995
 
SIRONA DENTAL SYSTEMS GMBH (1)
4,575,805 Method and apparatus for the fabrication of custom-shaped implants 488 1984
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (3)
5,041,138 Neomorphogenesis of cartilage in vivo from cell culture 356 1989
* 5,246,013 Probe, system and method for detecting cartilage degeneration 45 1992
6,382,028 Ultrasonic defect detection system 90 2000
 
THERICS, INC. (1)
2003/0173,695 Rapid prototyping and manufacturing process 65 2003
 
BIO RESEARCH (2)
5,413,116 Method and apparatus for diagnosing joints 55 1993
* 5,533,519 Method and apparatus for diagnosing joints 48 1995
 
CEMAX MEDICAL PRODUCTS, INC., A CORP. OF CA. (1)
4,436,684 Method of forming implantable prostheses for reconstructive surgery 290 1982
 
ALEXANDRIA RESEARCH TECHNOLOGIES, INC. (1)
7,520,901 Bicompartmental implants and method of use 39 2006
 
PLUS ENDOPROTHETIK AG (1)
6,383,228 Femoral hip-joint prosthesis with a logarithmically extending curvature 141 1999
 
CENTERPULSE ORTHOPEDICS INC. (8)
6,206,927 Surgically implantable knee prothesis 239 1999
6,558,421 Surgically implantable knee prosthesis 163 2000
6,855,165 Surgically implantable knee prosthesis having enlarged femoral surface 62 2002
6,866,684 Surgically implantable knee prosthesis having different tibial and femoral surface profiles 53 2002
6,893,463 Surgically implantable knee prosthesis having two-piece keyed components 68 2002
6,911,044 Surgically implantable knee prosthesis having medially shifted tibial surface 83 2002
6,923,831 Surgically implantable knee prosthesis having attachment apertures 104 2002
6,966,928 Surgically implantable knee prosthesis having keels 68 2002
 
ORTHOPAEDIC INNOVATIONS, INC. (1)
6,575,980 Method and apparatus for femoral resection 286 1999
 
MERRILL LYNCH BUSINESS FINANCIAL SERVICES INC. (1)
5,649,929 Knee joint flexion-gap distraction device 85 1995
 
MedIdea, LLC (6)
6,187,010 Bone cutting guides for use in the implantation of prosthetic joint components 171 1997
5,885,296 Bone cutting guides with removable housings for use in the implantation of prosthetic joint components 127 1997
5,897,559 Bone cutting guides for use in the implantation of prosthetic joint components 159 1997
5,916,220 Bone cutting guide and method to accommodate different-sized implants 132 1998
5,961,523 Bone cutting guides to accommodate variable thicknesses of augmentation for use in the implantation of prosthetic joint components 121 1998
6,102,916 Bone cutting guides with removable housings for use in the implantation of prosthetic joint components 136 1999
 
MESOBLAST INTERNATIONAL SÀRL (2)
5,197,985 Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells 269 1990
5,226,914 Method for treating connective tissue disorders 313 1990
 
ORTHO DEVELOPMENT CORPORATION (1)
6,379,388 Tibial prosthesis locking system and method of repairing knee joint 119 1999
 
GENERAL ELECTRIC COMPANY (1)
6,310,477 MR imaging of lesions and detection of malignant tumors 47 1999
 
Kabushiki Kaisha Biomaterial Universe Corporation of Japan (1)
5,314,478 Artificial bone connection prosthesis 256 1991
 
Biomedical Engineering Trust I (4)
5,507,820 Fixed bearing joint endoprosthesis 74 1994
5,683,468 Mobile bearing total joint replacement 110 1995
6,224,632 Prosthesis fixturing device 75 1996
6,344,043 Anterior-posterior femoral resection guide with set of detachable collets 87 2000
 
Resonex Holding Company (1)
* 5,445,152 Kinematic device for producing precise incremental flexing of the knee 58 1992
 
MATERIALISE N.V. (1)
5,768,134 Method for making a perfected medical model on the basis of digital image information of a part of the body 288 1996
 
The Dana Center for Orthopaedic Implants (1)
6,010,509 Patella resection drill and prosthesis implantation device 111 1998
 
ADVANCED BIO SURFACES, INC. (2)
2002/0127,264 Method and system for mammalian joint resurfacing 109 2002
2002/0183,850 Method and system for mammalian joint resurfacing 99 2002
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (11)
* 6,219,571 Magnetic resonance imaging using driven equilibrium fourier transform 90 1999
* 7,239,908 Assessing the condition of a joint and devising treatment 231 2000
* 2002/0087,274 Assessing the condition of a joint and preventing damage 174 2001
6,799,066 Technique for manipulating medical images 159 2001
* 7,184,814 Assessing the condition of a joint and assessing cartilage loss 193 2001
* 2004/0167,390 Assessing the condition of a joint and devising treatment 128 2004
2007/0015,995 Joint and cartilage diagnosis, assessment and modeling 123 2006
2007/0203,430 Assessing the Condition of a Joint and Assessing Cartilage Loss 118 2007
2007/0276,224 Assessing the Condition of a Joint and Devising Treatment 143 2007
2008/0015,433 Assessing the Condition of a Joint and Devising Treatment 97 2007
2009/0076,371 Joint and Cartilage Diagnosis, Assessment and Modeling 117 2008
 
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (1)
6,365,405 Compositions of chondrocytes, preparation and utilization 76 2000
 
ST. JUDE MEDICAL, INC. (1)
6,322,588 Medical devices with metal/polymer composites 173 1999
 
THURGAUER KANTONALBANK, A CORPORATION CHARTERED IN AND EXISTING UNDER THE LAWS OF SWITZERLAND, THAT MAINTAINS ITS PRINCIPAL OFFICES AT: (1)
* 5,554,190 Prosthesis component and a method of producing it 123 1994
 
ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE (2)
6,352,558 Method for promoting regeneration of surface cartilage in a damage joint 135 1999
6,576,015 Bone material and collagen combination for repair of injured joints 42 2001
 
METABOLIX, INC. (1)
6,838,493 Medical devices and applications of polyhydroxyalkanoate polymers 133 2002
 
BURKE, DENNIS W. (2)
5,474,559 Femoral milling instrumentation for use in total knee arthroplasty with optional cutting guide attachment 259 1993
5,601,563 Orthopaedic milling template with attachable cutting guide 191 1995
 
AVANTA ORTHOPAEDICS, LLC (2)
5,522,900 Prosthetic joint and method of manufacture 80 1993
5,549,690 Prosthetic thumb joint and method of manufacture 109 1994
 
LAWSON, KEVIN J., AN INDIVIDUAL (1)
6,146,422 Prosthetic nucleus replacement for surgical reconstruction of intervertebral discs and treatment method 210 1999
 
SYMMETRY MEDICAL MANUFACTURING, INC. (1)
5,597,379 Method and apparatus for femoral resection alignment 218 1994
 
ARTHROSURFACE INCORPORATED (1)
6,679,917 System and method for joint resurface repair 194 2002
 
AMERICAN IRON AND STEEL INSTITUTE (1)
6,057,927 Laser-ultrasound spectroscopy apparatus and method with detection of shear resonances for measuring anisotropy, thickness, and other properties 119 1998
 
HOWMEDICA INTERNATIONAL S. DE R.L. (1)
5,911,723 Surgical apparatus 164 1997
 
BAXTER INTERNATIONAL INC. (1)
4,627,853 Method of producing prostheses for replacement of articular cartilage and prostheses so produced 296 1985
 
ARTHROVISION, INC. (1)
6,560,476 Evaluating disease progression using magnetic resonance imaging 103 2000
 
INSTITUTE OF SOMATIC SCIENCES, THE (1)
* 6,310,619 Virtual reality, tissue-specific body model having user-variable tissue-specific attributes and a system and method for implementing the same 83 1998
 
CORIN LIMITED (1)
6,623,526 Knee prosthesis 96 1999
 
PRIVATDOZENT DR. NORBERT M. MEENEN (1)
6,319,712 Biohybrid articular surface replacement 72 1999
 
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (1)
* 6,585,666 Arthroscopic diagnostic probe to measure mechanical properties of articular cartilage 45 2001
 
LIFESHIELD SCIENCES LLC (17)
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
 
APERION BIOLOGICS, INC. (2)
6,093,204 Meniscal heterografts 102 1998
6,046,379 Meniscal xenografts 100 1998
 
TRIGON INCORPORATED (1)
5,246,530 Method of producing porous metal surface 112 1992
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
CONFORMIS, INC. (51)
8,932,363 Methods for determining meniscal size and shape and for devising treatment 0 2003
8,545,569 Patient selectable knee arthroplasty devices 19 2004
8,882,847 Patient selectable knee joint arthroplasty devices 3 2004
8,617,242 Implant device and method for manufacture 16 2008
8,951,260 Surgical cutting guide 0 2008
8,343,218 Methods and compositions for articular repair 44 2008
8,337,507 Methods and compositions for articular repair 45 2008
8,682,052 Implants for altering wear patterns of articular surfaces 9 2009
8,439,926 Patient selectable joint arthroplasty devices and surgical tools 28 2009
8,460,304 Joint arthroplasty devices and surgical tools 28 2009
8,377,129 Joint arthroplasty devices and surgical tools 47 2009
8,480,754 Patient-adapted and improved articular implants, designs and related guide tools 27 2010
8,500,740 Patient-specific joint arthroplasty devices for ligament repair 34 2010
8,709,089 Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces 13 2010
8,551,099 Surgical tools for arthroplasty 19 2010
8,366,771 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 42 2010
8,337,501 Patient selectable joint arthroplasty devices and surgical tools 59 2010
9,055,953 Methods and compositions for articular repair 0 2010
9,023,050 Surgical tools for arthroplasty 0 2010
8,768,028 Methods and compositions for articular repair 7 2010
8,690,945 Patient selectable knee arthroplasty devices 9 2010
8,585,708 Patient selectable joint arthroplasty devices and surgical tools 0 2010
8,945,230 Patient selectable knee joint arthroplasty devices 0 2010
8,771,365 Patient-adapted and improved orthopedic implants, designs, and related tools 7 2010
8,556,983 Patient-adapted and improved orthopedic implants, designs and related tools 20 2011
8,735,773 Implant device and method for manufacture 11 2011
8,623,026 Patient selectable joint arthroplasty devices and surgical tools incorporating anatomical relief 15 2011
8,974,539 Patient-adapted and improved articular implants, designs and related guide tools 0 2011
8,926,706 Patient-adapted and improved articular implants, designs and related guide tools 0 2011
8,906,107 Patient-adapted and improved orthopedic implants, designs and related tools 0 2011
8,657,827 Surgical tools for arthroplasty 13 2011
8,634,617 Methods for determining meniscal size and shape and for devising treatment 15 2011
8,638,998 Fusion of multiple imaging planes for isotropic imaging in MRI and quantitative image analysis using isotropic or near-isotropic imaging 15 2012
9,020,788 Patient-adapted and improved articular implants, designs and related guide tools 0 2012
8,641,716 Joint arthroplasty devices and surgical tools 15 2012
8,617,172 Joint arthroplasty devices and surgical tools 16 2012
8,568,479 Joint arthroplasty devices and surgical tools 17 2012
8,568,480 Joint arthroplasty devices and surgical tools 17 2012
8,562,611 Joint arthroplasty devices and surgical tools 19 2012
8,562,618 Joint arthroplasty devices and surgical tools 19 2012
8,561,278 Joint arthroplasty devices and surgical tools 19 2012
8,556,906 Joint arthroplasty devices and surgical tools 19 2012
8,556,907 Joint arthroplasty devices and surgical tools 19 2012
8,551,102 Joint arthroplasty devices and surgical tools 19 2012
8,551,103 Joint arthroplasty devices and surgical tools 19 2012
8,551,169 Joint arthroplasty devices and surgical tools 19 2012
8,529,630 Patient selectable joint arthroplasty devices and surgical tools 19 2012
8,998,915 Joint arthroplasty devices and surgical tools 0 2013
8,951,259 Patient selectable joint arthroplasty devices and surgical tools 0 2013
8,849,621 Patient selectable joint arthroplasty devices and surgical tools 0 2013
8,965,088 Methods for determining meniscal size and shape and for devising treatment 0 2014
 
Other [Check patent profile for assignment information] (1)
9,066,728 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 0 2012
 
GIVEN IMAGING LTD. (1)
* 8,582,853 Device, system and method for automatic detection of contractile activity in an image frame 0 2013
 
OTISMED CORPORATION (18)
8,460,302 Arthroplasty devices and related methods 17 2006
9,017,336 Arthroplasty devices and related methods 0 2007
8,460,303 Arthroplasty systems and devices, and related methods 10 2007
8,221,430 System and method for manufacturing arthroplasty jigs 31 2007
8,480,679 Generation of a computerized bone model representative of a pre-degenerated state and useable in the design and manufacture of arthroplasty devices 11 2008
8,734,455 Hip resurfacing surgical guide tool 1 2009
8,311,306 System and method for image segmentation in generating computer models of a joint to undergo arthroplasty 26 2009
8,777,875 System and method for manufacturing arthroplasty jigs having improved mating accuracy 6 2009
8,715,291 Arthroplasty system and related methods 0 2009
8,545,509 Arthroplasty system and related methods 8 2009
8,617,175 Unicompartmental customized arthroplasty cutting jigs and methods of making the same 17 2009
8,737,700 Preoperatively planning an arthroplasty procedure and generating a corresponding patient specific arthroplasty resection guide 1 2010
8,617,171 Preoperatively planning an arthroplasty procedure and generating a corresponding patient specific arthroplasty resection guide 5 2011
* 8,160,345 System and method for image segmentation in generating computer models of a joint to undergo arthroplasty 43 2011
D691719 Arthroplasty jig blank 8 2011
* 8,532,361 System and method for image segmentation in generating computer models of a joint to undergo arthroplasty 16 2012
8,968,320 System and method for manufacturing arthroplasty jigs 0 2012
8,483,469 System and method for image segmentation in generating computer models of a joint to undergo arthroplasty 11 2012
 
MICROPORT ORTHOPEDICS HOLDINGS INC. (2)
9,017,334 Patient specific surgical guide locator and mount 0 2010
8,808,303 Orthopedic surgical guide 0 2011
 
SYNARC INC. (2)
* 8,300,910 Pathology indicating measure related to cartilage structure and automatic quantification thereof 1 2007
* 2010/0220,907 Pathology indicating measure related to cartilage structure and automatic quantification thereof 1 2007
 
LABORATOIRES BODYCAD INC. (1)
D702349 Tibial prosthesis 0 2013
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (5)
* 8,369,926 Assessing the condition of a joint and devising treatment 41 2011
* 2011/0125,009 Assessing the Condition of a Joint and Devising Treatment 44 2011
* 8,306,601 Assessing the condition of a joint and devising treatment 58 2011
* 2012/0072,183 Assessing the Condition of a Joint and Devising Treatment 1 2011
8,862,202 Assessing the condition of a joint and preventing damage 1 2012
 
DESIGN VISIONARIES (2)
8,801,720 Total joint arthroplasty system 3 2006
8,801,719 Total joint arthroplasty system 1 2012
* Cited By Examiner

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