US Patent No: 8,036,729 - Analytics, PDF, Full Text and PAIR Access

Number of patents in Portfolio can not be more than 2000

Assessing the condition of a joint and devising treatment

ALSO PUBLISHED AS: 20040167390
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Abstract

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Methods are disclosed for assessing the condition of a cartilage in a joint, particularly a human knee. The methods include converting an image such as an MRI to a three dimensional map of the cartilage. The cartilage map can be correlated to a movement pattern of the joint to assess the affect of movement on cartilage wear. Changes in the thickness of cartilage over time can be determined so that therapies can be provided. Information on thickness of cartilage and curvature of cartilage or subchondral bone can be used to plan therapy. Information on movement pattern can be used to plan therapy.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYPALO ALTO, CA2092

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lang, Philipp Lexington, US 232 8535
Steines, Daniel Lexington, US 160 6199

Cited Art Landscape

Patent Info (Count) # Cites Year
 
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6,203,576 Complete knee joint prosthesis 161 1999
 
SIEMENS AKTIENGESELLSCHAFT (3)
* 6,334,066 Method for monitoring growth disorder therapy 38 1999
* 6,311,083 Method for determining an examination point for the diaphanoscopic examination of a being and device for realizing the same 8 2000
6,556,855 Method for the implementation of a perfusion measurement with magnetic resonance imaging 39 2001
 
CORNELL UNIVERSITY (1)
* 5,913,821 Diagnostic method and apparatus for assessing canine hip dysplasia 40 1997
 
GENZYME CORPORATION (4)
* 5,723,331 Methods and compositions for the repair of articular cartilage defects in mammals 217 1995
5,900,245 Compliant tissue sealants 217 1996
* 5,786,217 Methods and compositions for the repair of articular cartilage defects in mammals 259 1997
6,217,894 Compliant tissue sealants 170 2000
 
WHALEDENT INC. (1)
4,368,040 Dental impression tray for forming a dental prosthesis in situ 116 1981
 
SULZER BIOLOGICS INC. (1)
6,514,514 Device and method for regeneration and repair of cartilage lesions 106 1999
 
Fonar Corporation (3)
* 5,810,006 Multipositional MRI for kinematic studies of movable joints 55 1995
* 5,899,859 Multipositional MRI for kinematic studies of movable joints 100 1995
* 5,772,595 Multipositional MRI for kinematic studies of movable joints 50 1996
 
Artecal, Sciences, Inc. (1)
6,841,150 Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair 52 2002
 
OSIRIS THERAPEUTICS, INC. (1)
* 6,835,377 Osteoarthritis cartilage regeneration 141 1998
 
AESCULAP, INC. (1)
6,387,131 Knee prosthesis comprising a tibial wedge 90 2000
 
MUSCULOGRAPHICS, INC. (1)
* 5,682,886 Computer-assisted surgical system 601 1995
 
MICROPORT ORTHOPEDICS HOLDINGS INC. (5)
6,013,103 Medial pivot knee prosthesis 260 1997
6,156,069 Precision hip joint replacement method 191 1999
7,060,074 Instrumentation for minimally invasive unicompartmental knee replacement 157 2002
7,141,053 Methods of minimally invasive unicompartmental knee replacement 169 2002
2006/0235,421 Instrumentation for Minimally Invasive Unicompartmental Knee Replacement 103 2006
 
SMITH & NEPHEW ORTHOPAEDICS AG (1)
6,165,221 Implant 44 1999
 
Joint Medical Products Corporation (1)
4,888,021 Knee and patellar prosthesis 164 1988
 
METALPRAECIS BERCHEM + SCHABERG GESELLSCHAFT FUR METALLFORMGEBUNG MBH (1)
* 5,150,304 Method of making an implantable joint prosthesis 112 1990
 
Sulzer Medizinaltechnik AG (1)
5,501,687 Body for distributing bone cement for the anchoring of implants 114 1993
 
Artecel Sciences, Inc. (1)
6,429,013 Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair 137 2000
 
SMITH & NEPHEW, INC. (7)
4,673,409 Implant with attachment surface 91 1986
5,478,739 Three-dimensional stromal cell and tissue culture system 128 1992
5,842,477 Method for repairing cartilage 386 1996
5,928,945 Application of shear flow stress to chondrocytes or chondrocyte stem cells to produce cartilage 87 1996
6,120,541 Apparatus for use in grafting articular cartilage 83 1999
6,375,658 Cartilage grafting 152 2000
6,358,253 Repairing cartilage 150 2000
 
RadioMed Corporation (2)
8,320,995 Fiducial marker with rings 6 2007
8,320,995 Fiducial marker with rings 6 2007
 
Human Performance Technologies, Inc. (1)
4,813,436 Motion analysis system employing various operating modes 108 1987
 
ABS CORPORATION (6)
6,626,945 Cartilage repair plug 146 2001
2001/0039,455 Cartilage repair plug 152 2001
6,652,587 Method and system for mammalian joint resurfacing 211 2002
2002/0173,852 Method and system for mammalian joint resurfacing 110 2002
2006/0111,726 Method and kit for interpositional arthroplasty 73 2003
2007/0067,032 Meniscus preserving implant method and apparatus 87 2004
 
MITSUBISHI DENKI KABUSHIKI KAISHA (2)
6,151,521 Medical support system 50 1998
6,334,006 Loading device and electronic equipment system 37 1998
 
North Shore University Hospital Research Corporation (1)
5,769,899 Cartilage repair unit 368 1996
 
SMITH & NEPHEW RICHARDS INC. (5)
5,108,452 Modular hip prosthesis 200 1990
5,560,096 Method of manufacturing femoral knee implant 83 1995
5,575,793 Patella clamp apparatus 94 1995
5,683,470 Tibial trial prosthesis and bone preparation system 35 1995
5,702,463 Tibial prosthesis with polymeric liner and liner insertion/removal instrument 95 1996
 
ORTHOPHOENIX, LLC (1)
5,827,289 Inflatable device for use in surgical protocols relating to treatment of fractured or diseased bones 412 1996
 
W. L. GORE & ASSOCIATES, INC. (1)
6,328,765 Methods and articles for regenerating living tissue 238 1998
 
Vertegen, Inc. (2)
2007/0083,266 Devices and methods for treating facet joints, uncovertebral joints, costovertebral joints and other joints 132 2006
2007/0118,222 Intervertebral devices and methods 57 2006
 
MEDICAL CENTER OF CENTRAL GEORGIA, THE (1)
5,906,934 Mesenchymal stem cells for cartilage repair 268 1995
 
HEIMANN SYSTEMS (1)
5,687,210 Method and device for determining the attenuation function of an object with respect to the transmission of a reference material thickness 131 1996
 
INAMED MEDICAL PRODUCTS CORPORATION (1)
5,480,430 Shape-retaining shell for a fluid filled prosthesis 62 1994
 
Orthogene LLC (1)
2002/0016,543 Method for diagnosis of and prognosis for damaged tissue 40 2001
 
Huwmedica Inc. (1)
5,542,947 Slotted patella resection guide and stylus 146 1995
 
Sirona Dental Systems GmbH (1)
4,575,805 Method and apparatus for the fabrication of custom-shaped implants 491 1984
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (3)
5,041,138 Neomorphogenesis of cartilage in vivo from cell culture 364 1989
* 5,246,013 Probe, system and method for detecting cartilage degeneration 45 1992
6,382,028 Ultrasonic defect detection system 96 2000
 
MESOBLAST INTERNATIONAL SÀRL (2)
5,197,985 Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells 278 1990
5,226,914 Method for treating connective tissue disorders 324 1990
 
THERICS, INC. (1)
2003/0173,695 Rapid prototyping and manufacturing process 71 2003
 
BIO RESEARCH (2)
5,413,116 Method and apparatus for diagnosing joints 55 1993
* 5,533,519 Method and apparatus for diagnosing joints 48 1995
 
CEMAX MEDICAL PRODUCTS, INC., A CORP. OF CA. (1)
4,436,684 Method of forming implantable prostheses for reconstructive surgery 301 1982
 
PLUS ENDOPROTHETIK AG (1)
6,383,228 Femoral hip-joint prosthesis with a logarithmically extending curvature 150 1999
 
CENTERPULSE ORTHOPEDICS INC. (8)
6,206,927 Surgically implantable knee prothesis 252 1999
6,558,421 Surgically implantable knee prosthesis 171 2000
6,855,165 Surgically implantable knee prosthesis having enlarged femoral surface 62 2002
6,866,684 Surgically implantable knee prosthesis having different tibial and femoral surface profiles 54 2002
6,893,463 Surgically implantable knee prosthesis having two-piece keyed components 68 2002
6,911,044 Surgically implantable knee prosthesis having medially shifted tibial surface 83 2002
6,923,831 Surgically implantable knee prosthesis having attachment apertures 106 2002
6,966,928 Surgically implantable knee prosthesis having keels 69 2002
 
ORTHOPAEDIC INNOVATIONS, INC. (1)
6,575,980 Method and apparatus for femoral resection 298 1999
 
MERRILL LYNCH BUSINESS FINANCIAL SERVICES, INC. (1)
5,649,929 Knee joint flexion-gap distraction device 91 1995
 
MedIdea, LLC (6)
6,187,010 Bone cutting guides for use in the implantation of prosthetic joint components 181 1997
5,885,296 Bone cutting guides with removable housings for use in the implantation of prosthetic joint components 136 1997
5,897,559 Bone cutting guides for use in the implantation of prosthetic joint components 168 1997
5,916,220 Bone cutting guide and method to accommodate different-sized implants 141 1998
5,961,523 Bone cutting guides to accommodate variable thicknesses of augmentation for use in the implantation of prosthetic joint components 129 1998
6,102,916 Bone cutting guides with removable housings for use in the implantation of prosthetic joint components 145 1999
 
Ortho Development Corporation (1)
6,379,388 Tibial prosthesis locking system and method of repairing knee joint 121 1999
 
GENERAL ELECTRIC COMPANY (1)
6,310,477 MR imaging of lesions and detection of malignant tumors 48 1999
 
Kabushiki Kaisha Biomaterial Universe Corporation of Japan (1)
5,314,478 Artificial bone connection prosthesis 258 1991
 
Biomedical Engineering Trust I (4)
5,507,820 Fixed bearing joint endoprosthesis 74 1994
5,683,468 Mobile bearing total joint replacement 110 1995
6,224,632 Prosthesis fixturing device 81 1996
6,344,043 Anterior-posterior femoral resection guide with set of detachable collets 95 2000
 
Resonex Holding Company (1)
* 5,445,152 Kinematic device for producing precise incremental flexing of the knee 58 1992
 
MATERIALISE NV (1)
5,768,134 Method for making a perfected medical model on the basis of digital image information of a part of the body 302 1996
 
The Dana Center for Orthopaedic Implants (1)
6,010,509 Patella resection drill and prosthesis implantation device 122 1998
 
ADVANCED BIO SURFACES, INC. (2)
2002/0127,264 Method and system for mammalian joint resurfacing 117 2002
2002/0183,850 Method and system for mammalian joint resurfacing 106 2002
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (11)
* 6,219,571 Magnetic resonance imaging using driven equilibrium fourier transform 96 1999
* 7,239,908 Assessing the condition of a joint and devising treatment 248 2000
* 2002/0087,274 Assessing the condition of a joint and preventing damage 184 2001
6,799,066 Technique for manipulating medical images 161 2001
* 7,184,814 Assessing the condition of a joint and assessing cartilage loss 206 2001
* 2004/0167,390 Assessing the condition of a joint and devising treatment 137 2004
2007/0015,995 Joint and cartilage diagnosis, assessment and modeling 133 2006
2007/0203,430 Assessing the Condition of a Joint and Assessing Cartilage Loss 127 2007
2007/0276,224 Assessing the Condition of a Joint and Devising Treatment 153 2007
2008/0015,433 Assessing the Condition of a Joint and Devising Treatment 105 2007
2009/0076,371 Joint and Cartilage Diagnosis, Assessment and Modeling 127 2008
 
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (1)
6,365,405 Compositions of chondrocytes, preparation and utilization 83 2000
 
ST. JUDE MEDICAL, INC. (1)
6,322,588 Medical devices with metal/polymer composites 180 1999
 
THURGAUER KANTONALBANK, A CORPORATION CHARTERED IN AND EXISTING UNDER THE LAWS OF SWITZERLAND, THAT MAINTAINS ITS PRINCIPAL OFFICES AT: (1)
* 5,554,190 Prosthesis component and a method of producing it 131 1994
 
Ed. Geistlich Soehne AG Fuer Chemische Industrie (2)
6,352,558 Method for promoting regeneration of surface cartilage in a damage joint 142 1999
6,576,015 Bone material and collagen combination for repair of injured joints 42 2001
 
METABOLIX, INC. (1)
6,838,493 Medical devices and applications of polyhydroxyalkanoate polymers 140 2002
 
BURKE, DENNIS W. (2)
5,474,559 Femoral milling instrumentation for use in total knee arthroplasty with optional cutting guide attachment 274 1993
5,601,563 Orthopaedic milling template with attachable cutting guide 202 1995
 
AVANTA ORTHOPAEDICS, LLC (2)
5,522,900 Prosthetic joint and method of manufacture 81 1993
5,549,690 Prosthetic thumb joint and method of manufacture 110 1994
 
LAWSON, KEVIN J., AN INDIVIDUAL (1)
6,146,422 Prosthetic nucleus replacement for surgical reconstruction of intervertebral discs and treatment method 213 1999
 
SYMMETRY MEDICAL MANUFACTURING, INC. (1)
5,597,379 Method and apparatus for femoral resection alignment 227 1994
 
Arthrosurface Incorporated (1)
6,679,917 System and method for joint resurface repair 205 2002
 
AMERICAN IRON AND STEEL INSTITUTE (1)
6,057,927 Laser-ultrasound spectroscopy apparatus and method with detection of shear resonances for measuring anisotropy, thickness, and other properties 126 1998
 
HOWMEDICA INTERNATIONAL S. DE R.L. (1)
5,911,723 Surgical apparatus 174 1997
 
BAXTER INTERNATIONAL INC. (1)
4,627,853 Method of producing prostheses for replacement of articular cartilage and prostheses so produced 304 1985
 
ARTHROVISION, INC. (1)
6,560,476 Evaluating disease progression using magnetic resonance imaging 109 2000
 
INSTITUTE OF SOMATIC SCIENCES, THE (1)
* 6,310,619 Virtual reality, tissue-specific body model having user-variable tissue-specific attributes and a system and method for implementing the same 86 1998
 
CORIN LIMITED (1)
6,623,526 Knee prosthesis 97 1999
 
PRIVATDOZENT DR. NORBERT M. MEENEN (1)
6,319,712 Biohybrid articular surface replacement 72 1999
 
ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE (1)
* 6,585,666 Arthroscopic diagnostic probe to measure mechanical properties of articular cartilage 46 2001
 
LIFESHIELD SCIENCES LLC (17)
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
 
APERION BIOLOGICS, INC. (2)
6,093,204 Meniscal heterografts 109 1998
6,046,379 Meniscal xenografts 107 1998
 
TRIGON INCORPORATED (1)
5,246,530 Method of producing porous metal surface 116 1992
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
CONFORMIS, INC. (56)
8,932,363 Methods for determining meniscal size and shape and for devising treatment 0 2003
8,545,569 Patient selectable knee arthroplasty devices 24 2004
8,882,847 Patient selectable knee joint arthroplasty devices 4 2004
8,617,242 Implant device and method for manufacture 21 2008
8,951,260 Surgical cutting guide 2 2008
8,343,218 Methods and compositions for articular repair 49 2008
8,337,507 Methods and compositions for articular repair 50 2008
8,682,052 Implants for altering wear patterns of articular surfaces 14 2009
8,439,926 Patient selectable joint arthroplasty devices and surgical tools 33 2009
8,460,304 Joint arthroplasty devices and surgical tools 33 2009
8,377,129 Joint arthroplasty devices and surgical tools 53 2009
8,480,754 Patient-adapted and improved articular implants, designs and related guide tools 32 2010
8,500,740 Patient-specific joint arthroplasty devices for ligament repair 41 2010
8,709,089 Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces 18 2010
8,551,099 Surgical tools for arthroplasty 24 2010
8,366,771 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 47 2010
8,337,501 Patient selectable joint arthroplasty devices and surgical tools 64 2010
9,055,953 Methods and compositions for articular repair 0 2010
9,023,050 Surgical tools for arthroplasty 0 2010
8,768,028 Methods and compositions for articular repair 12 2010
8,690,945 Patient selectable knee arthroplasty devices 14 2010
8,585,708 Patient selectable joint arthroplasty devices and surgical tools 0 2010
8,945,230 Patient selectable knee joint arthroplasty devices 0 2010
8,771,365 Patient-adapted and improved orthopedic implants, designs, and related tools 12 2010
8,556,983 Patient-adapted and improved orthopedic implants, designs and related tools 25 2011
8,735,773 Implant device and method for manufacture 16 2011
8,623,026 Patient selectable joint arthroplasty devices and surgical tools incorporating anatomical relief 19 2011
8,974,539 Patient-adapted and improved articular implants, designs and related guide tools 0 2011
8,926,706 Patient-adapted and improved articular implants, designs and related guide tools 0 2011
8,906,107 Patient-adapted and improved orthopedic implants, designs and related tools 1 2011
8,657,827 Surgical tools for arthroplasty 18 2011
9,107,679 Patient selectable joint arthroplasty devices and surgical tools 0 2011
9,084,617 Patient selectable joint arthroplasty devices and surgical tools 0 2011
8,634,617 Methods for determining meniscal size and shape and for devising treatment 21 2011
8,638,998 Fusion of multiple imaging planes for isotropic imaging in MRI and quantitative image analysis using isotropic or near-isotropic imaging 20 2012
9,020,788 Patient-adapted and improved articular implants, designs and related guide tools 0 2012
9,066,728 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 0 2012
8,641,716 Joint arthroplasty devices and surgical tools 20 2012
8,617,172 Joint arthroplasty devices and surgical tools 21 2012
8,568,479 Joint arthroplasty devices and surgical tools 22 2012
8,568,480 Joint arthroplasty devices and surgical tools 22 2012
8,562,611 Joint arthroplasty devices and surgical tools 24 2012
8,562,618 Joint arthroplasty devices and surgical tools 24 2012
8,561,278 Joint arthroplasty devices and surgical tools 24 2012
8,556,906 Joint arthroplasty devices and surgical tools 24 2012
8,556,907 Joint arthroplasty devices and surgical tools 24 2012
8,551,102 Joint arthroplasty devices and surgical tools 24 2012
8,551,103 Joint arthroplasty devices and surgical tools 24 2012
8,551,169 Joint arthroplasty devices and surgical tools 24 2012
8,529,630 Patient selectable joint arthroplasty devices and surgical tools 24 2012
9,107,680 Patient selectable joint arthroplasty devices and surgical tools 0 2012
8,998,915 Joint arthroplasty devices and surgical tools 0 2013
9,072,531 Patient selectable joint arthroplasty devices and surgical tools 0 2013
8,951,259 Patient selectable joint arthroplasty devices and surgical tools 2 2013
8,849,621 Patient selectable joint arthroplasty devices and surgical tools 0 2013
8,965,088 Methods for determining meniscal size and shape and for devising treatment 0 2014
 
Other [Check patent profile for assignment information] (2)
9,113,914 Method for forming a patient specific surgical guide mount 0 2010
9,113,921 Patient selectable joint arthroplasty devices and surgical tools 0 2011
 
GIVEN IMAGING LTD. (1)
* 8,582,853 Device, system and method for automatic detection of contractile activity in an image frame 0 2013
 
OTISMED CORPORATION (18)
8,460,302 Arthroplasty devices and related methods 19 2006
9,017,336 Arthroplasty devices and related methods 0 2007
8,460,303 Arthroplasty systems and devices, and related methods 10 2007
8,221,430 System and method for manufacturing arthroplasty jigs 38 2007
8,480,679 Generation of a computerized bone model representative of a pre-degenerated state and useable in the design and manufacture of arthroplasty devices 11 2008
8,734,455 Hip resurfacing surgical guide tool 1 2009
8,311,306 System and method for image segmentation in generating computer models of a joint to undergo arthroplasty 32 2009
8,777,875 System and method for manufacturing arthroplasty jigs having improved mating accuracy 8 2009
8,715,291 Arthroplasty system and related methods 0 2009
8,545,509 Arthroplasty system and related methods 8 2009
8,617,175 Unicompartmental customized arthroplasty cutting jigs and methods of making the same 21 2009
8,737,700 Preoperatively planning an arthroplasty procedure and generating a corresponding patient specific arthroplasty resection guide 1 2010
8,617,171 Preoperatively planning an arthroplasty procedure and generating a corresponding patient specific arthroplasty resection guide 5 2011
* 8,160,345 System and method for image segmentation in generating computer models of a joint to undergo arthroplasty 51 2011
D691719 Arthroplasty jig blank 8 2011
* 8,532,361 System and method for image segmentation in generating computer models of a joint to undergo arthroplasty 18 2012
8,968,320 System and method for manufacturing arthroplasty jigs 0 2012
8,483,469 System and method for image segmentation in generating computer models of a joint to undergo arthroplasty 11 2012
 
MICROPORT ORTHOPEDICS HOLDINGS INC. (3)
9,017,334 Patient specific surgical guide locator and mount 0 2010
8,808,303 Orthopedic surgical guide 0 2011
9,089,342 Patient specific surgical guide locator and mount 0 2012
 
SYNARC INC. (2)
* 8,300,910 Pathology indicating measure related to cartilage structure and automatic quantification thereof 1 2007
* 2010/0220,907 Pathology indicating measure related to cartilage structure and automatic quantification thereof 1 2007
 
LABORATOIRES BODYCAD INC. (1)
D702349 Tibial prosthesis 0 2013
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (5)
* 8,369,926 Assessing the condition of a joint and devising treatment 47 2011
* 2011/0125,009 Assessing the Condition of a Joint and Devising Treatment 49 2011
* 8,306,601 Assessing the condition of a joint and devising treatment 64 2011
* 2012/0072,183 Assessing the Condition of a Joint and Devising Treatment 1 2011
8,862,202 Assessing the condition of a joint and preventing damage 1 2012
 
DESIGN VISIONARIES (2)
8,801,720 Total joint arthroplasty system 7 2006
8,801,719 Total joint arthroplasty system 1 2012
* Cited By Examiner

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