US Patent No: 8,036,729 - Analytics, PDF, Full Text and PAIR Access

Number of patents in Portfolio can not be more than 2000

Assessing the condition of a joint and devising treatment

ALSO PUBLISHED AS: 20040167390
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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods are disclosed for assessing the condition of a cartilage in a joint, particularly a human knee. The methods include converting an image such as an MRI to a three dimensional map of the cartilage. The cartilage map can be correlated to a movement pattern of the joint to assess the affect of movement on cartilage wear. Changes in the thickness of cartilage over time can be determined so that therapies can be provided. Information on thickness of cartilage and curvature of cartilage or subchondral bone can be used to plan therapy. Information on movement pattern can be used to plan therapy.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYPALO ALTO, CA2047

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lang, Philipp Lexington, MA 327 12630
Steines, Daniel Palo Alto, CA 242 10191

Cited Art Landscape

Patent Info (Count) # Cites Year
 
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6,056,756 Femoral tensing and sizing device 137 1998
6,106,529 Epicondylar axis referencing drill guide 140 1998
 
GROUPE CONTROLE DEDIENNE GDC SOCIETE DE DROIT FRANCAIS (1)
6,203,576 Complete knee joint prosthesis 142 1999
 
SIEMENS AKTIENGESELLSCHAFT (3)
* 6,334,066 Method for monitoring growth disorder therapy 36 1999
* 6,311,083 Method for determining an examination point for the diaphanoscopic examination of a being and device for realizing the same 8 2000
6,556,855 Method for the implementation of a perfusion measurement with magnetic resonance imaging 37 2001
 
CORNELL UNIVERSITY (1)
* 5,913,821 Diagnostic method and apparatus for assessing canine hip dysplasia 38 1997
 
GENZYME CORPORATION (4)
* 5,723,331 Methods and compositions for the repair of articular cartilage defects in mammals 208 1995
5,900,245 Compliant tissue sealants 201 1996
* 5,786,217 Methods and compositions for the repair of articular cartilage defects in mammals 236 1997
6,217,894 Compliant tissue sealants 158 2000
 
WHALEDENT INC. (1)
4,368,040 Dental impression tray for forming a dental prosthesis in situ 103 1981
 
Fonar Corporation (3)
* 5,810,006 Multipositional MRI for kinematic studies of movable joints 53 1995
* 5,899,859 Multipositional MRI for kinematic studies of movable joints 88 1995
* 5,772,595 Multipositional MRI for kinematic studies of movable joints 48 1996
 
Artecal, Sciences, Inc. (1)
6,841,150 Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair 50 2002
 
OSIRIS THERAPEUTICS, INC. (1)
* 6,835,377 Osteoarthritis cartilage regeneration 131 1998
 
AESCULAP (1)
6,387,131 Knee prosthesis comprising a tibial wedge 78 2000
 
MUSCULOGRAPHICS, INC. (1)
* 5,682,886 Computer-assisted surgical system 555 1995
 
MICROPORT ORTHOPEDICS HOLDINGS INC. (5)
6,013,103 Medial pivot knee prosthesis 235 1997
6,156,069 Precision hip joint replacement method 168 1999
7,060,074 Instrumentation for minimally invasive unicompartmental knee replacement 135 2002
7,141,053 Methods of minimally invasive unicompartmental knee replacement 146 2002
2006/0235,421 Instrumentation for Minimally Invasive Unicompartmental Knee Replacement 85 2006
 
SMITH & NEPHEW ORTHOPAEDICS AG (1)
6,165,221 Implant 42 1999
 
Joint Medical Products Corporation (1)
4,888,021 Knee and patellar prosthesis 160 1988
 
METALPRAECIS BERCHEM + SCHABERG GESELLSCHAFT FUR METALLFORMGEBUNG MBH (1)
* 5,150,304 Method of making an implantable joint prosthesis 103 1990
 
SULZER MEDIZINALTECHNIK AG (1)
5,501,687 Body for distributing bone cement for the anchoring of implants 101 1993
 
Artecel Sciences, Inc. (1)
6,429,013 Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair 124 2000
 
SMITH & NEPHEW, INC. (7)
4,673,409 Implant with attachment surface 89 1986
5,478,739 Three-dimensional stromal cell and tissue culture system 116 1992
5,842,477 Method for repairing cartilage 361 1996
5,928,945 Application of shear flow stress to chondrocytes or chondrocyte stem cells to produce cartilage 85 1996
6,120,541 Apparatus for use in grafting articular cartilage 71 1999
6,375,658 Cartilage grafting 134 2000
6,358,253 Repairing cartilage 131 2000
 
RadioMed Corporation (2)
8,320,995 Fiducial marker with rings 4 2007
8,320,995 Fiducial marker with rings 4 2007
 
Human Performance Technologies, Inc. (1)
4,813,436 Motion analysis system employing various operating modes 104 1987
 
ABS CORPORATION (6)
6,626,945 Cartilage repair plug 132 2001
2001/0039,455 Cartilage repair plug 133 2001
6,652,587 Method and system for mammalian joint resurfacing 193 2002
2002/0173,852 Method and system for mammalian joint resurfacing 96 2002
2006/0111,726 Method and kit for interpositional arthroplasty 67 2003
2007/0067,032 Meniscus preserving implant method and apparatus 82 2004
 
MITSUBISHI DENKI KABUSHIKI KAISHA (2)
6,151,521 Medical support system 47 1998
6,334,006 Loading device and electronic equipment system 35 1998
 
NORTH SHORE UNIVERSITY HOSPITAL RESEARCH CORPORATION (1)
5,769,899 Cartilage repair unit 340 1996
 
SMITH & NEPHEW RICHARDS INC. (5)
5,108,452 Modular hip prosthesis 193 1990
5,560,096 Method of manufacturing femoral knee implant 75 1995
5,575,793 Patella clamp apparatus 77 1995
5,683,470 Tibial trial prosthesis and bone preparation system 35 1995
5,702,463 Tibial prosthesis with polymeric liner and liner insertion/removal instrument 90 1996
 
W. L. GORE & ASSOCIATES, INC. (1)
6,328,765 Methods and articles for regenerating living tissue 219 1998
 
Vertegen, Inc. (2)
2007/0083,266 Devices and methods for treating facet joints, uncovertebral joints, costovertebral joints and other joints 118 2006
2007/0118,222 Intervertebral devices and methods 47 2006
 
MEDICAL CENTER OF CENTRAL GEORGIA, THE (1)
5,906,934 Mesenchymal stem cells for cartilage repair 243 1995
 
HEIMANN SYSTEMS (1)
5,687,210 Method and device for determining the attenuation function of an object with respect to the transmission of a reference material thickness 119 1996
 
INAMED MEDICAL PRODUCTS CORPORATION (1)
5,480,430 Shape-retaining shell for a fluid filled prosthesis 59 1994
 
Orthogene LLC (1)
2002/0016,543 Method for diagnosis of and prognosis for damaged tissue 38 2001
 
Huwmedica Inc. (1)
5,542,947 Slotted patella resection guide and stylus 125 1995
 
SIRONA DENTAL SYSTEMS GMBH (1)
4,575,805 Method and apparatus for the fabrication of custom-shaped implants 476 1984
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (3)
5,041,138 Neomorphogenesis of cartilage in vivo from cell culture 344 1989
* 5,246,013 Probe, system and method for detecting cartilage degeneration 43 1992
6,382,028 Ultrasonic defect detection system 83 2000
 
THERICS, INC. (1)
2003/0173,695 Rapid prototyping and manufacturing process 60 2003
 
BIO RESEARCH (2)
5,413,116 Method and apparatus for diagnosing joints 53 1993
* 5,533,519 Method and apparatus for diagnosing joints 48 1995
 
CEMAX MEDICAL PRODUCTS, INC., A CORP. OF CA. (1)
4,436,684 Method of forming implantable prostheses for reconstructive surgery 277 1982
 
ALEXANDRIA RESEARCH TECHNOLOGIES, INC. (1)
7,520,901 Bicompartmental implants and method of use 37 2006
 
PLUS ENDOPROTHETIK AG (1)
6,383,228 Femoral hip-joint prosthesis with a logarithmically extending curvature 130 1999
 
CENTERPULSE ORTHOPEDICS INC. (8)
6,206,927 Surgically implantable knee prothesis 224 1999
6,558,421 Surgically implantable knee prosthesis 155 2000
6,855,165 Surgically implantable knee prosthesis having enlarged femoral surface 59 2002
6,866,684 Surgically implantable knee prosthesis having different tibial and femoral surface profiles 51 2002
6,893,463 Surgically implantable knee prosthesis having two-piece keyed components 64 2002
6,911,044 Surgically implantable knee prosthesis having medially shifted tibial surface 79 2002
6,923,831 Surgically implantable knee prosthesis having attachment apertures 97 2002
6,966,928 Surgically implantable knee prosthesis having keels 65 2002
 
ORTHOPAEDIC INNOVATIONS, INC. (1)
6,575,980 Method and apparatus for femoral resection 266 1999
 
MERRILL LYNCH BUSINESS FINANCIAL SERVICES INC. (1)
5,649,929 Knee joint flexion-gap distraction device 79 1995
 
MedIdea, LLC (6)
6,187,010 Bone cutting guides for use in the implantation of prosthetic joint components 158 1997
5,885,296 Bone cutting guides with removable housings for use in the implantation of prosthetic joint components 118 1997
5,897,559 Bone cutting guides for use in the implantation of prosthetic joint components 149 1997
5,916,220 Bone cutting guide and method to accommodate different-sized implants 123 1998
5,961,523 Bone cutting guides to accommodate variable thicknesses of augmentation for use in the implantation of prosthetic joint components 113 1998
6,102,916 Bone cutting guides with removable housings for use in the implantation of prosthetic joint components 128 1999
 
MESOBLAST INTERNATIONAL SÀRL (2)
5,197,985 Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells 257 1990
5,226,914 Method for treating connective tissue disorders 300 1990
 
ORTHO DEVELOPMENT CORPORATION (1)
6,379,388 Tibial prosthesis locking system and method of repairing knee joint 112 1999
 
GENERAL ELECTRIC COMPANY (1)
6,310,477 MR imaging of lesions and detection of malignant tumors 44 1999
 
Kabushiki Kaisha Biomaterial Universe Corporation of Japan (1)
5,314,478 Artificial bone connection prosthesis 248 1991
 
Biomedical Engineering Trust I (4)
5,507,820 Fixed bearing joint endoprosthesis 72 1994
5,683,468 Mobile bearing total joint replacement 107 1995
6,224,632 Prosthesis fixturing device 69 1996
6,344,043 Anterior-posterior femoral resection guide with set of detachable collets 79 2000
 
Resonex Holding Company (1)
* 5,445,152 Kinematic device for producing precise incremental flexing of the knee 56 1992
 
MATERIALISE N.V. (1)
5,768,134 Method for making a perfected medical model on the basis of digital image information of a part of the body 272 1996
 
The Dana Center for Orthopaedic Implants (1)
6,010,509 Patella resection drill and prosthesis implantation device 104 1998
 
ADVANCED BIO SURFACES, INC. (2)
2002/0127,264 Method and system for mammalian joint resurfacing 102 2002
2002/0183,850 Method and system for mammalian joint resurfacing 91 2002
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (11)
* 6,219,571 Magnetic resonance imaging using driven equilibrium fourier transform 84 1999
* 7,239,908 Assessing the condition of a joint and devising treatment 216 2000
* 2002/0087,274 Assessing the condition of a joint and preventing damage 162 2001
6,799,066 Technique for manipulating medical images 150 2001
* 7,184,814 Assessing the condition of a joint and assessing cartilage loss 181 2001
* 2004/0167,390 Assessing the condition of a joint and devising treatment 118 2004
2007/0015,995 Joint and cartilage diagnosis, assessment and modeling 112 2006
2007/0203,430 Assessing the Condition of a Joint and Assessing Cartilage Loss 108 2007
2007/0276,224 Assessing the Condition of a Joint and Devising Treatment 131 2007
2008/0015,433 Assessing the Condition of a Joint and Devising Treatment 90 2007
2009/0076,371 Joint and Cartilage Diagnosis, Assessment and Modeling 107 2008
 
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (1)
6,365,405 Compositions of chondrocytes, preparation and utilization 70 2000
 
ST. JUDE MEDICAL, INC. (1)
6,322,588 Medical devices with metal/polymer composites 164 1999
 
THURGAUER KANTONALBANK, A CORPORATION CHARTERED IN AND EXISTING UNDER THE LAWS OF SWITZERLAND, THAT MAINTAINS ITS PRINCIPAL OFFICES AT: (1)
* 5,554,190 Prosthesis component and a method of producing it 113 1994
 
ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE (2)
6,352,558 Method for promoting regeneration of surface cartilage in a damage joint 125 1999
6,576,015 Bone material and collagen combination for repair of injured joints 41 2001
 
METABOLIX, INC. (1)
6,838,493 Medical devices and applications of polyhydroxyalkanoate polymers 126 2002
 
BURKE, DENNIS W. (2)
5,474,559 Femoral milling instrumentation for use in total knee arthroplasty with optional cutting guide attachment 244 1993
5,601,563 Orthopaedic milling template with attachable cutting guide 181 1995
 
AVANTA ORTHOPAEDICS, LLC (2)
5,522,900 Prosthetic joint and method of manufacture 75 1993
5,549,690 Prosthetic thumb joint and method of manufacture 106 1994
 
LAWSON, KEVIN J., AN INDIVIDUAL (1)
6,146,422 Prosthetic nucleus replacement for surgical reconstruction of intervertebral discs and treatment method 201 1999
 
SYMMETRY MEDICAL MANUFACTURING, INC. (1)
5,597,379 Method and apparatus for femoral resection alignment 208 1994
 
ARTHROSURFACE INCORPORATED (1)
6,679,917 System and method for joint resurface repair 181 2002
 
AMERICAN IRON AND STEEL INSTITUTE (1)
6,057,927 Laser-ultrasound spectroscopy apparatus and method with detection of shear resonances for measuring anisotropy, thickness, and other properties 113 1998
 
HOWMEDICA INTERNATIONAL S. DE R.L. (1)
5,911,723 Surgical apparatus 154 1997
 
BAXTER INTERNATIONAL INC. (1)
4,627,853 Method of producing prostheses for replacement of articular cartilage and prostheses so produced 282 1985
 
ARTHROVISION, INC. (1)
6,560,476 Evaluating disease progression using magnetic resonance imaging 96 2000
 
INSTITUTE OF SOMATIC SCIENCES, THE (1)
* 6,310,619 Virtual reality, tissue-specific body model having user-variable tissue-specific attributes and a system and method for implementing the same 76 1998
 
CORIN LIMITED (1)
6,623,526 Knee prosthesis 91 1999
 
PRIVATDOZENT DR. NORBERT M. MEENEN (1)
6,319,712 Biohybrid articular surface replacement 70 1999
 
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (1)
* 6,585,666 Arthroscopic diagnostic probe to measure mechanical properties of articular cartilage 42 2001
 
LIFESHIELD SCIENCES LLC (17)
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
2004/0158,312 Braided endoluminal device having tapered filaments 10 2003
 
APERION BIOLOGICS, INC. (2)
6,093,204 Meniscal heterografts 94 1998
6,046,379 Meniscal xenografts 94 1998
 
TRIGON INCORPORATED (1)
5,246,530 Method of producing porous metal surface 105 1992
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
CONFORMIS, INC. (47)
8,932,363 Methods for determining meniscal size and shape and for devising treatment 0 2003
8,545,569 Patient selectable knee arthroplasty devices 14 2004
8,882,847 Patient selectable knee joint arthroplasty devices 0 2004
8,617,242 Implant device and method for manufacture 11 2008
8,951,260 Surgical cutting guide 0 2008
8,343,218 Methods and compositions for articular repair 39 2008
8,337,507 Methods and compositions for articular repair 38 2008
8,682,052 Implants for altering wear patterns of articular surfaces 4 2009
8,439,926 Patient selectable joint arthroplasty devices and surgical tools 23 2009
8,460,304 Joint arthroplasty devices and surgical tools 22 2009
8,377,129 Joint arthroplasty devices and surgical tools 41 2009
8,480,754 Patient-adapted and improved articular implants, designs and related guide tools 22 2010
8,500,740 Patient-specific joint arthroplasty devices for ligament repair 24 2010
8,709,089 Minimally invasive joint implant with 3-dimensional geometry matching the articular surfaces 8 2010
8,551,099 Surgical tools for arthroplasty 14 2010
8,366,771 Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty 37 2010
8,337,501 Patient selectable joint arthroplasty devices and surgical tools 53 2010
8,768,028 Methods and compositions for articular repair 2 2010
8,690,945 Patient selectable knee arthroplasty devices 4 2010
8,585,708 Patient selectable joint arthroplasty devices and surgical tools 0 2010
8,945,230 Patient selectable knee joint arthroplasty devices 0 2010
8,771,365 Patient-adapted and improved orthopedic implants, designs, and related tools 2 2010
8,556,983 Patient-adapted and improved orthopedic implants, designs and related tools 15 2011
8,735,773 Implant device and method for manufacture 4 2011
8,623,026 Patient selectable joint arthroplasty devices and surgical tools incorporating anatomical relief 9 2011
8,974,539 Patient-adapted and improved articular implants, designs and related guide tools 0 2011
8,926,706 Patient-adapted and improved articular implants, designs and related guide tools 0 2011
8,906,107 Patient-adapted and improved orthopedic implants, designs and related tools 0 2011
8,657,827 Surgical tools for arthroplasty 8 2011
8,634,617 Methods for determining meniscal size and shape and for devising treatment 10 2011
8,638,998 Fusion of multiple imaging planes for isotropic imaging in MRI and quantitative image analysis using isotropic or near-isotropic imaging 10 2012
8,641,716 Joint arthroplasty devices and surgical tools 10 2012
8,617,172 Joint arthroplasty devices and surgical tools 11 2012
8,568,479 Joint arthroplasty devices and surgical tools 12 2012
8,568,480 Joint arthroplasty devices and surgical tools 12 2012
8,562,611 Joint arthroplasty devices and surgical tools 14 2012
8,562,618 Joint arthroplasty devices and surgical tools 14 2012
8,561,278 Joint arthroplasty devices and surgical tools 14 2012
8,556,906 Joint arthroplasty devices and surgical tools 14 2012
8,556,907 Joint arthroplasty devices and surgical tools 14 2012
8,551,102 Joint arthroplasty devices and surgical tools 14 2012
8,551,103 Joint arthroplasty devices and surgical tools 14 2012
8,551,169 Joint arthroplasty devices and surgical tools 14 2012
8,529,630 Patient selectable joint arthroplasty devices and surgical tools 14 2012
8,951,259 Patient selectable joint arthroplasty devices and surgical tools 0 2013
8,849,621 Patient selectable joint arthroplasty devices and surgical tools 0 2013
8,965,088 Methods for determining meniscal size and shape and for devising treatment 0 2014
 
GIVEN IMAGING LTD. (1)
* 8,582,853 Device, system and method for automatic detection of contractile activity in an image frame 0 2013
 
MICROPORT ORTHOPEDICS HOLDINGS INC. (1)
8,808,303 Orthopedic surgical guide 0 2011
 
OTISMED CORPORATION (17)
8,460,302 Arthroplasty devices and related methods 13 2006
8,460,303 Arthroplasty systems and devices, and related methods 9 2007
8,221,430 System and method for manufacturing arthroplasty jigs 26 2007
8,480,679 Generation of a computerized bone model representative of a pre-degenerated state and useable in the design and manufacture of arthroplasty devices 10 2008
8,734,455 Hip resurfacing surgical guide tool 0 2009
8,311,306 System and method for image segmentation in generating computer models of a joint to undergo arthroplasty 23 2009
8,777,875 System and method for manufacturing arthroplasty jigs having improved mating accuracy 2 2009
8,715,291 Arthroplasty system and related methods 0 2009
8,545,509 Arthroplasty system and related methods 7 2009
8,617,175 Unicompartmental customized arthroplasty cutting jigs and methods of making the same 13 2009
8,737,700 Preoperatively planning an arthroplasty procedure and generating a corresponding patient specific arthroplasty resection guide 0 2010
8,617,171 Preoperatively planning an arthroplasty procedure and generating a corresponding patient specific arthroplasty resection guide 3 2011
* 8,160,345 System and method for image segmentation in generating computer models of a joint to undergo arthroplasty 34 2011
D691719 Arthroplasty jig blank 7 2011
* 8,532,361 System and method for image segmentation in generating computer models of a joint to undergo arthroplasty 12 2012
8,968,320 System and method for manufacturing arthroplasty jigs 0 2012
8,483,469 System and method for image segmentation in generating computer models of a joint to undergo arthroplasty 10 2012
 
SYNARC INC. (1)
* 8,300,910 Pathology indicating measure related to cartilage structure and automatic quantification thereof 1 2007
 
LABORATOIRES BODYCAD INC. (1)
D702349 Tibial prosthesis 0 2013
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (5)
* 8,369,926 Assessing the condition of a joint and devising treatment 36 2011
* 2011/0125,009 Assessing the Condition of a Joint and Devising Treatment 39 2011
* 8,306,601 Assessing the condition of a joint and devising treatment 52 2011
* 2012/0072,183 Assessing the Condition of a Joint and Devising Treatment 1 2011
8,862,202 Assessing the condition of a joint and preventing damage 0 2012
 
DESIGN VISIONARIES (2)
8,801,720 Total joint arthroplasty system 0 2006
8,801,719 Total joint arthroplasty system 0 2012
* Cited By Examiner

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7.5 Year Payment $3600.00 $1800.00 $900.00 Apr 11, 2019
11.5 Year Payment $7400.00 $3700.00 $1850.00 Apr 11, 2023
Fee Large entity fee small entity fee micro entity fee
Surcharge - 3.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00