
US Patent No: 8,041,428
Number of patents in Portfolio can not be more than 2000
Electrical stimulation treatment of hypotension
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Oct 18, 2011
Issued date -
Nov 4, 2009
filing date -
12/612,177
serial no -
In Force
status
Importance
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Abstract
The present invention includes methods and devices for treating hypotension, such as in cases of shock, including septic shock, anaphylactic shock and hypovolemia. The method includes the step of applying at least one electrical impulse to at least one selected region of a parasympathetic nervous system of the patient. The electrical impulse is sufficient to modulate one or more nerves of the parasympathetic nervous system to increase the ratio of blood pressure to heart rate and relieve the condition and/or extend the patient's life.
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First Claim
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International Classification(s)
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Cited Art
| Patent Info | (Count) | # Cites | Year |
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| 6,871,099 Fully implantable microstimulator for spinal cord stimulation as a therapy for chronic pain | 62 | 2001 | |
| 2002/0161,403 Deep brain stimulation system for the treatment of parkinson's disease or other disorders | 2001 | ||
| 2002/0161,403 Deep brain stimulation system for the treatment of parkinson's disease or other disorders | 2001 | ||
| 2002/0161,403 Deep brain stimulation system for the treatment of parkinson's disease or other disorders | 2001 | ||
| 2002/0161,403 Deep brain stimulation system for the treatment of parkinson's disease or other disorders | 2001 | ||
| 2002/0161,403 Deep brain stimulation system for the treatment of parkinson's disease or other disorders | 2001 | ||
| 2002/0161,403 Deep brain stimulation system for the treatment of parkinson's disease or other disorders | 2001 | ||
| 2002/0161,403 Deep brain stimulation system for the treatment of parkinson's disease or other disorders | 2001 | ||
| 2002/0161,403 Deep brain stimulation system for the treatment of parkinson's disease or other disorders | 2001 | ||
| 7,203,548 Cavernous nerve stimulation via unidirectional propagation of action potentials | 43 | 2002 | |
| 7,292,890 Vagus nerve stimulation via unidirectional propagation of action potentials | 72 | 2002 | |
| 2004/0106,954 Treatment of congestive heart failure | 74 | 2003 | |
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| 2005/0065,567 Therapy control based on cardiopulmonary status | 36 | 2004 | |
| 2005/0076,909 Synergistic use of medical devices for detecting medical disorders | 30 | 2004 | |
| 2005/0080,461 System and method for moderating a therapy delivered during sleep using physiologic data acquired during non-sleep | 31 | 2004 | |
| 2006/0229,677 Transvascular neural stimulation device | 47 | 2005 | |
| 2006/0259,107 System for selective activation of a nerve trunk using a transvascular reshaping lead | 27 | 2005 | |
| 2005/0283,197 Systems and methods for hypotension | 40 | 2005 | |
| 2006/0282,145 Vascularly stabilized peripheral nerve cuff assembly | 20 | 2005 | |
| 2006/0135,998 System and method for closed-loop neural stimulation | 58 | 2005 | |
| 2007/0150,006 Neural stimulator to treat sleep disordered breathing | 19 | 2005 | |
| 2007/0239,210 SYSTEM AND METHOD FOR CLOSED-LOOP NEURAL STIMULATION | 22 | 2006 | |
| 2008/0004,672 SYSTEM FOR PROVIDING DIABETIC THERAPY | 9 | 2006 | |
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| 6,006,134 Method and device for electronically controlling the beating of a heart using venous electrical stimulation of nerve fibers | 231 | 1998 | |
| 6,327,503 Method and apparatus for sensing and stimulating gastrointestinal tract on-demand | 93 | 1998 | |
| 6,083,249 Apparatus for sensing and stimulating gastrointestinal tract on-demand | 140 | 1998 | |
| 6,612,983 Pancreatic secretion response to stimulation test protocol | 70 | 2000 | |
| 6,752,765 Method and apparatus for monitoring heart rate and abnormal respiration | 111 | 2000 | |
| 6,738,667 Implantable medical device for treating cardiac mechanical dysfunction by electrical stimulation | 56 | 2000 | |
| 7,225,019 Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure | 17 | 2003 | |
| 2004/0172,080 Method and apparatus for detecting change in intrathoracic electrical impedance | 62 | 2003 | |
| 2005/0075,702 Device and method for inhibiting release of pro-inflammatory mediator | 60 | 2004 | |
| 2005/0015,117 Method, system and device for treating disorders of the pelvic floor by electrical stimulation of and the delivery of drugs to the left and right pudendal nerves | 27 | 2004 | |
| 2006/0095,079 Sub-mucosal medical device implantation | 10 | 2004 | |
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| 6,273,907 Bronchial stenter | 80 | 1997 | |
| 6,083,255 Bronchial stenter | 142 | 1997 | |
| 5,972,026 Bronchial stenter having diametrically adjustable electrodes | 135 | 1998 | |
| 6,299,633 Bronchial stenter | 106 | 1998 | |
| 6,200,333 Bronchial stenter | 151 | 1998 | |
| 6,283,988 Bronchial stenter having expandable electrodes | 104 | 1999 | |
| 6,283,989 Method of treating a bronchial tube with a bronchial stenter having diametrically adjustable electrodes | 113 | 1999 | |
| 6,411,852 Modification of airways by application of energy | 99 | 1999 | |
| 2005/0010,270 Method of treating airways in the lung | 39 | 2004 | |
| 2005/0187,579 Method for treating an asthma attack | 24 | 2005 | |
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| 5,540,730 Treatment of motility disorders by nerve stimulation | 347 | 1995 | |
| 5,707,400 Treating refractory hypertension by nerve stimulation | 288 | 1995 | |
| 6,587,719 Treatment of obesity by bilateral vagus nerve stimulation | 168 | 1999 | |
| 6,609,025 Treatment of obesity by bilateral sub-diaphragmatic nerve stimulation | 158 | 2001 | |
| 6,819,956 Optimal method and apparatus for neural modulation for the treatment of neurological disease, particularly movement disorders | 148 | 2001 | |
| 2007/0027,483 Stimulating cranial nerve to treat disorders associated with the thyroid gland | 7 | 2005 | |
| 2007/0027,496 Stimulating cranial nerve to treat pulmonary disorder | 29 | 2005 | |
| 2007/0093,870 Cranial nerve stimulation to treat eating disorders | 20 | 2005 | |
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| 6,060,454 Compositions, apparatus and methods for facilitating surgical procedures | 49 | 1998 | |
| 6,043,273 Compositions, apparatus and methods for facilitating surgical procedures | 52 | 1999 | |
| 6,087,394 Compositions, apparatus and methods for facilitating surgical procedures | 53 | 1999 | |
| 6,127,410 Compositions, apparatus and methods for facilitating surgical procedures | 52 | 1999 | |
| 6,141,589 Switch control for external pacing system | 44 | 1999 | |
| 6,711,436 Compositions, apparatus and methods for facilitating surgical procedures | 61 | 1999 | |
| 6,101,412 Compositions, apparatus and methods for facilitating surgical procedures | 57 | 1999 | |
| 6,414,018 Compositions, apparatus and methods for facilitating surgical procedures | 36 | 2000 | |
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| 6,258,087 Expandable electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions | 189 | 1999 | |
| 6,273,886 Integrated tissue heating and cooling apparatus | 178 | 1999 | |
| 6,402,744 Systems and methods for forming composite lesions to treat dysfunction in sphincters and adjoining tissue regions | 42 | 1999 | |
| 6,464,697 Stomach and adjoining tissue regions in the esophagus | 73 | 1999 | |
| 6,547,776 Systems and methods for treating tissue in the crura | 68 | 2000 | |
| 6,562,034 Electrodes for creating lesions in tissue regions at or near a sphincter | 51 | 2002 | |
| 6,712,074 Systems and methods for forming composite lesions to treat dysfunction in sphincters and adjoining tissue regions | 52 | 2002 | |
| 2005/0107,829 Methods for treating the cardia of the stomach | 29 | 2004 | |
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| 6,934,583 Implantable lead and method for stimulating the vagus nerve | 91 | 2001 | |
| 6,937,896 Sympathetic nerve stimulator and/or pacemaker | 53 | 2002 | |
| 7,092,755 System and method of cardiac pacing during sleep apnea | 46 | 2003 | |
| 7,123,961 Stimulation of autonomic nerves | 62 | 2004 | |
| 2005/0165,456 Digital electrode for cardiac rhythm management | 44 | 2004 | |
| 2007/0299,476 Sympathetic afferent activation for adjusting autonomic tone | 8 | 2006 | |
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| 6,885,888 Electrical stimulation of the sympathetic nerve chain | 144 | 2001 | |
| 2005/0065,562 Electrical stimulation of the sympathetic nerve chain | 70 | 2004 | |
| 2005/0065,574 Methods of affecting hypothalamic-related conditions | 62 | 2004 | |
| 2005/0065,573 Electrical stimulation of the sympathetic nerve chain | 75 | 2004 | |
| 2005/0177,192 Neurostimulation for affecting sleep disorders | 77 | 2005 | |
| 2008/0183,248 APPARATUS AND METHODS FOR TREATING PULMONARY CONDITIONS | 17 | 2008 | |
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| 2002/0072,738 ACTIVELY COOLED ELECTRODE ASSEMBLIES FOR FORMING LESIONS TO TREAT DYSFUNCTION IN SPHINCTERS AND ADJOINING TISSUE REGIONS | 18 | 1999 | |
| 6,325,798 Vacuum-assisted systems and methods for treating sphincters and adjoining tissue regions | 123 | 1999 | |
| 6,423,058 Assemblies to visualize and treat sphincters and adjoining tissue regions | 69 | 1999 | |
| 6,440,128 Actively cooled electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions | 51 | 1999 | |
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| 2007/0106,337 Methods And Apparatus For Treating Disorders Through Neurological And/Or Muscular Intervention | 28 | 2006 | |
| 2007/0106,338 Direct and Indirect Control of Muscle for the Treatment of Pathologies | 16 | 2006 | |
| 2007/0106,339 Electrical stimulation treatment of bronchial constriction | 23 | 2006 | |
| 2007/0191,902 Methods and apparatus for treating anaphylaxis using electrical modulation | 15 | 2006 | |
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| 6,356,786 Method of treating palmar hyperhydrosis by electrical stimulation of the sympathetic nervous chain | 88 | 2000 | |
| 6,438,423 Method of treating complex regional pain syndromes by electrical stimulation of the sympathetic nerve chain | 110 | 2000 | |
| 6,356,787 Method of treating facial blushing by electrical stimulation of the sympathetic nerve chain | 64 | 2000 | |
| 6,609,030 Method of treating psychiatric diseases by neuromodulation within the dorsomedial thalamus | 76 | 2000 | |
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| 6,633,779 Treatment of asthma and respiratory disease by means of electrical neuro-receptive waveforms | 42 | 2001 | |
| 6,681,136 Device and method to modulate blood pressure by electrical waveforms | 39 | 2001 | |
| 6,957,106 Implantable method to regulate blood pressure by means of coded nerve signals | 17 | 2004 | |
| 6,937,903 Respiratory control by means of neuro-electrical coded signals | 19 | 2004 | |
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| 2005/0143,788 Treatment of female fertility conditions through modulation of the autonomic nervous system | 32 | 2003 | |
| 2005/0256,028 Treatment of conditions through modulation of the autonomic nervous system during at least one predetermined menstrual cycle phase | 21 | 2004 | |
| 2005/0153,885 Treatment of conditions through modulation of the autonomic nervous system | 77 | 2004 | |
| 2005/0240,241 Treatment of conditions through modulation of the autonomic nervous system | 52 | 2005 | |
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| 5,405,362 Interactive external defibrillation and drug injection system | 121 | 1993 | |
| 6,342,221 Antibody conjugate compositions for selectively inhibiting VEGF | 73 | 2000 | |
| 6,755,849 Method for delivering energy to tissue and apparatus | 60 | 2002 | |
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| 6,656,960 Methods of performing vagal-induced asystole | 60 | 2002 | |
| 7,072,720 Devices and methods for vagus nerve stimulation | 43 | 2002 | |
| 7,142,910 Methods of indirectly stimulating the vagus nerve with an electrical field | 33 | 2004 | |
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| 2004/0172,084 Method and apparatus for treatment of gastro-esophageal reflux disease (GERD) | 38 | 2003 | |
| 7,167,750 Obesity treatment with electrically induced vagal down regulation | 73 | 2004 | |
| 2007/0135,846 Vagal obesity treatment | 18 | 2007 | |
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| 6,610,713 Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation | 127 | 2001 | |
| 2005/0125,044 Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation | 23 | 2004 | |
| 2006/0178,703 Treating inflammatory disorders by electrical vagus nerve stimulation | 22 | 2005 | |
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| 2006/0100,671 Stimulation of the amygdalohippocampal complex to treat neurological conditions | 15 | 2005 | |
| 2007/0060,954 Method of using spinal cord stimulation to treat neurological disorders or conditions | 24 | 2006 | |
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| 2004/0176,803 Electromagnetic therapy device and methods | 21 | 2003 | |
| 2004/0176,805 Electromagnetic therapy device and methods | 25 | 2003 | |
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| 2004/0147,969 System for detecting, diagnosing, and treating cardiovascular disease | 110 | 2003 | |
| 6,970,742 Method for detecting, diagnosing, and treating cardiovascular disease | 118 | 2003 | |
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| 2005/0228,459 Renal nerve stimulation method and apparatus for treatment of patients | 32 | 2005 | |
| 2005/0234,523 Renal nerve stimulation method and apparatus for treatment of patients | 54 | 2005 | |
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| 6,366,814 External stimulator for adjunct (add-on) treatment for neurological, neuropsychiatric, and urological disorders | 159 | 2000 | |
| 2005/0149,146 Method and system to provide therapy for obesity and other medical disorders, by providing electrical pules to symapthetic nerves or vagal nerve(s) with rechargeable implanted pulse generator | 75 | 2005 | |
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| 2005/0261,747 Method and system to control respiration by means of neuro-electrical coded signals | 33 | 2005 | |
| 2006/0287,679 Method and system to control respiration by means of confounding neuro-electrical signals | 18 | 2006 | |
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| 6,347,247 Electrically induced vessel vasodilation | 76 | 1999 | |
| 6,865,416 Electrically induced vessel vasodilation | 77 | 2001 | |
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| 5,107,835 Electrotherapeutic treatment | 41 | 1989 | |
| 5,109,846 Apparatus and method for electrotherapeutic treatment of structures associated with the eye | 25 | 1990 | |
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| 2005/0251,213 Automated caregiving device with prompting based on caregiver progress | 14 | 2004 | |
| 2005/0267,536 Automated pediatric defibrillator | 14 | 2005 | |
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| 2007/0156,182 Electrical stimulation device and method for the treatment of dysphagia | 8 | 2006 | |
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| 4,989,604 Electromagnetic device | 21 | 1985 | |
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| 6,463,327 Stimulatory device and methods to electrically stimulate the phrenic nerve | 53 | 2000 | |
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| 2004/0073,278 Method of and device for therapeutic illumination of internal organs and tissues | 28 | 2003 | |
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| 2005/0182,463 Polymer compositions and methods for their use | 31 | 2004 | |
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| 6,363,937 System and methods for electrosurgical treatment of the digestive system | 174 | 1998 | |
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| 2004/0230,252 Method and apparatus for affecting the autonomic nervous system | 24 | 2004 | |
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| 2005/0065,553 Applications of vagal stimulation | 68 | 2004 | |
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| 6,629,951 Devices for creating collateral in the lungs | 101 | 2001 | |
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| 2006/0200,219 Systems and methods for differentiating and/or identifying tissue regions innervated by targeted nerves for diagnostic and/or therapeutic purposes | 20 | 2006 | |
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| 2005/0222,651 Therapeutic device and method | 14 | 2005 | |
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| 6,872,206 Methods for treating the cardia of the stomach | 30 | 2002 | |
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| 2006/0167,498 Method, apparatus, and surgical technique for autonomic neuromodulation for the treatment of disease | 50 | 2005 | |
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| 5,135,480 Transdermal drug delivery device | 100 | 1990 | |
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| 6,198,970 Method and apparatus for treating oropharyngeal respiratory and oral motor neuromuscular disorders with electrical stimulation | 71 | 1999 | |
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| 6,341,236 Vagal nerve stimulation techniques for treatment of epileptic seizures | 243 | 1999 | |
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| 5,620,463 Electrophysiological conditioning system and method | 28 | 1994 | |
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| 2004/0127,942 Medical device for neural stimulation and controlled drug delivery | 78 | 2003 | |
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| 2005/0171,575 Electrically induced vessel vasodilation | 29 | 2005 | |
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| 4,351,330 Emergency internal defibrillation | 77 | 1980 | |
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| 2005/0238,693 Process for the preparation and activation of susbstances and a means of producing same | 13 | 2004 | |
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| 2005/0187,581 Methods of treating disorders with electric fields | 5 | 2004 | |
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| 5,956,501 Disease simulation system and method | 335 | 1997 | |
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| 7,031,745 Cellular phone combined physiological condition examination and processing device | 17 | 2003 | |
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| 6,973,347 Local cardiac motion control using applied electrical signals and mechanical force | 5 | 2000 | |
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| 2005/0216,062 Multi-functional electrical stimulation system | 14 | 2003 | |
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| 4,305,402 Method for transcutaneous electrical stimulation | 129 | 1979 | |
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| 6,913,616 Laser ionization therapy system and method | 12 | 2003 | |
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| 2007/0225,768 Electric modulation of sympathetic nervous system | 14 | 2007 | |
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| 6,871,092 APPARATUS DESIGNED TO MODULATE THE NEUROVEGETATIVE SYSTEM AND INTEGRATE ITS ACTION WITH THAT OF THE CENTRAL NERVOUS SYSTEM; APPLICATIONS IN THE TREATMENT OF THE VASCULAR SYSTEM AND ORTHOPAEDIC DISORDERS | 29 | 2002 | |
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| 5,405,366 Adhesive hydrogels having extended use lives and process for the preparation of same | 60 | 1992 | |
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| 7,228,167 Method and apparatus for detecting vagus nerve stimulation | 10 | 2004 | |
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| 6,974,224 Modularized light processing of body components | 22 | 2003 | |
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| 5,152,286 Method of microwave resonance therapy and device therefor | 37 | 1991 | |
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| 5,658,322 Bio-active frequency generator and method | 83 | 1995 | |
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| 5,690,692 Bio-active frequency generator and method | 44 | 1997 | |
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| 2004/0030,368 Phototherapeutical method and system for the treatment of inflammatory and hyperproliferative disorders of the nasal mucosa | 21 | 2003 | |
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| 2005/0171,438 High speed spectral domain functional optical coherence tomography and optical doppler tomography for in vivo blood flow dynamics and tissue structure | 2004 | ||
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| 4,503,863 Method and apparatus for transcutaneous electrical stimulation | 95 | 1981 | |
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| 2001/0001,008 Transmitter/receiver for GMSK and Offset-QAM | 2000 | ||
| 2002/0010,495 Method and apparatus for treating oropharyngeal, respiratory and oral motor neuromuscular disorders with electrical stimulation | 27 | 2001 | |
| 6,676,686 Noninvasive detection and activation of the lymphatic system in treating disease and alleviating pain | 16 | 2001 | |
| 6,675,047 Electromagnetic-field therapy method and device | 16 | 2001 | |
| 6,838,429 Atopic dermatitis treatment method | 12 | 2001 | |
| 2002/0091,379 Method for treating an asthma attack | 43 | 2001 | |
| 6,778,854 Methods of indirectly stimulating the vagus nerve with an electrical field | 66 | 2002 | |
| 7,310,552 Apparatus for indirectly stimulating the vagus nerve with an electrical field | 15 | 2002 | |
| 2002/0143,373 System and method for therapeutic application of energy | 31 | 2002 | |
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| 2002/0198,574 Automatic sobriety training and reconditioning system | 20 | 2002 | |
| 2003/0093,128 Method and apparatus for treating oropharyngeal, respiratory and oral motor neuromuscular disorders with electrical stimulation | 28 | 2002 | |
| 2004/0147,988 Method of treatment using one or more of a group of the "THERMA-KLOTH" products | 12 | 2003 | |
| 2003/0181,949 Medical therapy apparatus | 13 | 2003 | |
| 2005/0182,288 Systems and methods for therapeutically treating neuro-psychiatric disorders and other illnesses | 26 | 2004 | |
| 2005/0222,635 Potency package two | 12 | 2004 | |
| 2005/0010,263 Neurostimulation unit for immobilizing the heart during cardiosurgical operations | 51 | 2004 | |
| 2005/0090,722 Method and apparatus for providing UV light to blood | 12 | 2004 | |
| 2005/0222,628 Implantable device for pain control and other medical treatments | 20 | 2004 | |
| 2005/0228,054 Methods for treating eye disorders | 12 | 2005 | |
| 2005/0277,993 System and method for managing detrimental cardiac remodeling | 25 | 2005 | |
| 2005/0228,460 Renal nerve stimulation method and apparatus for treatment of patients | 32 | 2005 | |
Patent Citation Ranking
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 3.5 Year Payment | $1600.00 | $800.00 | $400.00 | Apr 18, 2015 |
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Apr 18, 2019 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Apr 18, 2023 |
| Fee | Large entity fee | small entity fee | micro entity fee |
|---|---|---|---|
| Surcharge - 3.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 7.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |