Use of impedance-based cytological profiling to classify cellular response profiles upon exposure to biologically active agents
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United States of America Patent
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Oct 18, 2011
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May 29, 2008
app pub date -
Sep 20, 2007
filing date -
Sep 20, 2006
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Abstract
The present invention provides methods of multi-dimensional profiling of biologically active agents and determining their effects on biological systems. The methods of the present invention include real-time impedance monitoring of cellular responses to biologically active agents and categorization of cellular kinetic profiles into mechanism specific cellular response profile groups. The grouping of similar cellular response profiles allows the correlation between agent and mechanism, thus allowing for the identification of potential therapeutic applications of agents or further study of cellular responses or mechanisms.
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