Methods for analysis of PDEF and survivin as interconnected cancer biomarkers and targets for personalized medicine
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United States of America Patent
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Oct 25, 2011
Grant Date -
Mar 26, 2009
app pub date -
Aug 6, 2008
filing date -
Aug 6, 2007
priority date (Note) -
Expired
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Abstract
Provided are methods for determining whether an individual is a candidate to receive treatment with a DNA methylation inhibitor. The method can be performed a biological sample of cancerous tissue of the individual. Determining that PDEF expression is absent or low and survivin expression is present identifies the individual as a candidate to receive a treatment with a DNA methylation inhibitor. The method also includes communicating the result of identifying an individual as a candidate for receiving a DNA methylation inhibitor to a health care provider.
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