Gravity-assisted mixing methods

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United States of America Patent

PATENT NO 8048375
SERIAL NO

12333335

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Abstract

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A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector.

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Patent Owner(s)

Patent OwnerAddress
GEN-PROBE INCORPORATED9620 CHESAPEAKE DRIVE #210 SAN DIEGO CALIFORNIA 92123 U S A
BIOLUCENT LLC250 CAMPUS DRIVE MARLBOROUGH MA 01752
CYTYC CORPORATION250 CAMPUS DRIVE MARLBOROUGH MA 01752
HOLOGIC INC250 CAMPUS DRIVE MARLBOROUGH MA 01752
SUROS SURGICAL SYSTEMS INC6100 TECHNOLOGY CENTER DRIVE NORTHWEST TECHNOLOGY CENTER INDIANAPOLIS IN 46278
THIRD WAVE TECHNOLOGIES INC250 CAMPUS DRIVE MARLBOROUGH MA 01752
CYTYC SURGICAL PRODUCTS LIMITED PARTNERSHIP250 CAMPUS DRIVE MARLBOROUGH MA 01752

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Breidenthal, Scott S Oceanside, US 14 542
Fan, Sara H San Diego, US 10 508
Lee, Richard S San Diego, US 23 611
Nelson, Norman C San Diego, US 77 2248
Scott, Matthew J Oceanside, US 15 542
Taylor, Jason A Windham, US 17 1360

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