Antivenom composition containing Fab fragments

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United States of America Patent

PATENT NO 8048414
SERIAL NO

08405454

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Abstract

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fragments. IgG antibodies are obtained by passing an antibody containing source through an antigen-polyacrylamide gel. These processes can be used to purify a wide variety of antibodies which can be used as therapeutic agents and as diagnostic agents. Antivenins produced by these processes have substantially reduced foreign protein levels and hence are less likely to produce immunogenic reactions. Bulk, unprocessed antibody sources may be utilized and, for reasons of process simplification, are preferred.

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Patent Owner(s)

  • BTG INTERNATIONAL, INC.;JOHN B. SULLIVAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Russell, Findlay E Tucson, US 2 23
Sullivan, John B Tucson, US 3 40

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