Dendritic cell co-stimulatory molecules
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United States of America Patent
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Nov 8, 2011
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app pub date -
Oct 31, 2007
filing date -
Apr 28, 2000
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Abstract
A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.
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