US Patent No: 8,062,355 - Analytics, PDF, Full Text and PAIR Access

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Self-expandable medical instrument for treating defects in a patient's heart

ALSO PUBLISHED AS: 20070142906

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Abstract

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The invention relates to a self-expandable medical instrument (100) for treating defects in a patient's heart, in particular for the transvascular implantation of a prosthetic heart valve (30), wherein the medical instrument (100) is introducible into the body of a patient in a minimally-invasive procedure using a catheter system (40) and comprises a stent (1) made of a flexible mesh (2) of thin wires or filaments (2'). In order to realize a positioning of medical instrument (100) in the patient's heart which is as precise as possible and to securely anchor same there, it is provided for the stent (1) composed of the flexible mesh (2) to exhibit in the expanded state of the medical instrument (100) a distal retention area (10) with a laterally-inverted beaded portion (12) which is engageable in at least one pocket (51) of the patient's defective heart valve (50), a proximal retention area (20), and a center area (15) positioned between the distal and the proximal retention area (10, 20).

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
JENAVALVE TECHNOLOGY, INC.WILMINGTON, DE22

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ferrari, Markus Jena, DE 42 790
Figulla, Hans-Reiner Jena, DE 30 726

Cited Art Landscape

Patent Info (Count) # Cites Year
 
EDWARDS LIFESCIENCES CORPORATION (45)
5,061,277 Flexible cardiac valvular support prosthesis 314 1988
5,002,566 Calcification mitigation of bioprosthetic implants 69 1989
5,197,979 Stentless heart valve and holder 102 1990
5,104,407 Selectively flexible annuloplasty ring 256 1990
5,336,258 Stentless heart valve and holder 88 1992
5,549,666 Natural tissue valve prostheses having variably complaint leaflets 82 1994
5,928,281 Tissue heart valves 126 1997
5,880,242 Nonpolymeric epoxy compounds for cross linking biological tissue and bioprosthetic grafts prepared thereby 29 1997
6,001,126 Stentless bioprosthetic heart valve with coronary protuberances and related methods for surgical repair of defective heart valves 64 1997
6,102,944 Methods of tissue heart valve assembly 131 1999
6,231,602 Aortic annuloplasty ring 160 1999
6,558,418 Flexible heart valve 114 1999
6,342,070 Stentless bioprosthetic heart valve with patent coronary protuberances and method of surgical use thereof 58 1999
6,338,740 Flexible heart valve leaflets 126 2000
6,344,044 Apparatus and methods for delivery of intraluminal prosthesis 62 2000
6,454,799 Minimally-invasive heart valves and methods of use 311 2000
6,585,766 Cloth-covered stents for tissue heart valves 79 2000
6,808,529 Apparatus and methods for delivery of intraluminal prostheses 60 2001
6,736,845 Holder for flexible heart valve 115 2001
2003/0050,694 Methods and apparatuses for deploying minimally-invasive heart valves 217 2001
7,141,064 Compressed tissue for heart valve leaflets 45 2002
6,767,362 Minimally-invasive heart valves and methods of use 213 2002
7,399,315 Minimally-invasive heart valve with cusp positioners 78 2003
6,945,997 Heart valves and suture rings therefor 92 2003
7,137,184 Continuous heart valve support frame and method of manufacture 67 2003
2004/0148,018 Flexible heart valve and associated connecting band 94 2003
7,381,218 System and method for implanting a two-part prosthetic heart valve 114 2004
7,318,278 Method of manufacture of a heart valve support frame 28 2005
2006/0293,745 Anatomically approximate prosthetic mitral heart valve 30 2005
2006/0229,719 Highly flexible heart valve connecting band 41 2005
2007/0005,131 Heart valve delivery system 114 2005
2006/0009,842 Contoured heart valve suture rings 71 2005
2007/0088,431 Heart valve delivery system with valve catheter 172 2005
2007/0112,422 Transapical heart valve delivery system and method 136 2005
7,473,275 Stress absorbing flexible heart valve frame 27 2006
2006/0229,718 Stress absorbing flexible heart valve frame 24 2006
2007/0244,551 Holders for prosthetic aortic heart valves 25 2006
2006/0287,717 Methods for rapid deployment of prosthetic heart valves 77 2006
2006/0287,719 Rapid deployment prosthetic heart valve 57 2006
2007/0123,979 Apparatus, system, and method for treatment of posterior leaflet prolapse 35 2006
2008/0021,546 System for deploying balloon-expandable heart valves 45 2006
2008/0154,355 Implantable prosthetic valve assembly and method of making the same 102 2006
2008/0065,011 INTEGRATED HEART VALVE DELIVERY SYSTEM 97 2007
2008/0102,439 BIOLOGICAL TISSUE FOR SURGICAL IMPLANTATION 29 2007
2008/0269,878 MINIMALLY-INVASIVE HEART VALVE WITH CUSP POSITIONERS 106 2008
 
COOK MEDICAL TECHNOLOGIES LLC (18)
6,200,336 Multiple-sided intraluminal medical device 317 1999
6,508,833 Multiple-sided intraluminal medical device 312 2001
6,974,474 Multiple-sided intraluminal medical device 140 2002
7,081,132 Flexible barb for anchoring a prosthesis 72 2003
2004/0117,004 Stent and method of forming a stent with integral barbs 206 2003
2007/0260,327 Artificial Valve Prosthesis with Improved Flow Dynamics 53 2004
2004/0260,389 Artificial valve prosthesis with improved flow dynamics 206 2004
2005/0222,668 Flareable branch vessel prosthesis and method 77 2004
2006/0058,864 Balloon flareable branch vessel prosthesis and method 56 2004
2006/0111,770 Implantable vascular device comprising a bioabsorbable frame 27 2005
2007/0021,826 Intralumenally implantable frames 30 2006
2007/0038,291 Intralumenally-implantable frames 36 2006
2007/0093,887 Artificial valve with center leaflet attachment 46 2006
2007/0100,435 Artificial prostheses with preferred geometries 73 2006
2007/0162,103 Implantable device with remodelable material and covering material 87 2006
2008/0033,534 Flexible Barb for Anchoring a Prosthesis 32 2007
2008/0097,586 IMPLANTABLE VASCULAR DEVICE 25 2007
2008/0200,977 Artificial Valve Prostheses with a Free Leaflet Portion 26 2008
 
COOK INCORPORATED (10)
5,035,706 Percutaneous stent and method for retrieval thereof 600 1989
5,456,713 Expandable transluminal graft prosthesis for repairs of aneurysm and method for implanting 350 1993
5,755,777 Expandable transluminal graft prosthesis for repair of aneurysm 165 1996
2005/0096,736 Percutaneous heart valve devices 140 2004
2005/0149,166 Branch vessel prosthesis with anchoring device and method 64 2004
2005/0171,597 Helical stent for branched vessel prosthesis 51 2004
2005/0171,598 Aorta and branch vessel stent grafts and method 76 2004
2007/0179,592 Branch vessel prosthesis with positional indicator system and method 58 2004
2005/0267,560 Implantable bioabsorbable valve support frame 125 2005
2007/0038,295 Artificial valve prosthesis having a ring frame 76 2006
 
EDWARDS LIFESCIENCES PVT, INC. (8)
6,893,460 Implantable prosthetic valve 272 2001
6,908,481 Value prosthesis for implantation in body channels 282 2002
6,730,118 Implantable prosthetic valve 330 2002
2004/0039,436 Implantable prosthetic valve 239 2003
* 2005/0075,725 Implantable prosthetic valve with non-laminar flow 95 2003
7,393,360 Implantable prosthetic valve 86 2005
2008/0004,688 IMPLANTABLE PROSTHETIC VALVE 36 2007
2008/0275,549 IMPLANTABLE PROSTHETIC VALVE WITH NON-LAMINAR FLOW 27 2008
 
MEDTRONIC COREVALVE LLC (8)
6,830,584 Device for replacing a cardiac valve by percutaneous route 213 2002
7,329,278 Prosthetic valve for transluminal delivery 102 2006
2006/0265,056 Heart valve prosthesis and methods of manufacture and use 157 2006
2007/0043,435 Non-cylindrical prosthetic valve system for transluminal delivery 169 2006
2007/0239,271 Systems and methods for loading a prosthesis onto a minimally invasive delivery system 72 2006
2008/0215,143 ASSEMBLY FOR PLACING A PROSTHETIC VALVE IN A DUCT IN THE BODY 86 2007
2008/0140,189 SYSTEM AND METHOD FOR TRANSAPICAL DELIVERY OF AN ANNULUS ANCHORED SELF-EXPANDING VALVE 125 2007
2008/0133,003 PROSTHETIC VALVE FOR TRANSLUMINAL DELIVERY 85 2008
 
MEDTRONIC, INC. (8)
5,279,612 Dynamic fixation of porcine aortic valves 57 1991
5,509,930 Stentless heart valve 64 1993
6,509,145 Process for reducing mineralization of tissue used in transplantation 43 2001
6,790,230 Vascular implant 184 2002
7,078,163 Process for reducing mineralization of tissue used in transplantation 38 2002
2005/0119,736 Bioprosthetic tissue preparation with synthetic hydrogels 35 2004
7,238,200 Apparatus and methods for making leaflets and valve prostheses including such leaflets 56 2005
2007/0203,576 APPARATUS AND METHODS FOR MAKING LEAFLETS AND VALVE PROSTHESES INCLUDING SUCH LEAFLETS 56 2007
 
JENAVALVE TECHNOLOGY, INC. (7)
6,254,564 Left ventricular conduit with blood vessel graft 85 1999
7,198,646 Device for fastening and anchoring cardiac valve prostheses 95 2001
6,881,199 Left ventricular conduit with blood vessel graft 63 2001
2005/0033,220 Left ventricular conduit with blood vessel graft 30 2004
2007/0005,129 Anchoring system for implantable heart valve prostheses 120 2006
2007/0142,906 Self-expandable medical instrument for treating defects in a patient's heart 68 2006
2008/0262,602 Methods and conduits for flowing blood from a heart chamber to a blood vessel 43 2008
 
MEDTRONIC VENTOR TECHNOLOGIES LTD. (7)
7,201,772 Fluid flow prosthetic device 194 2004
2008/0071,361 Leaflet-sensitive valve fixation member 106 2007
2008/0071,362 Valve prosthesis implantation techniques 92 2007
2008/0071,363 Valve prosthesis fixation techniques using sandwiching 116 2007
2008/0071,366 Axial-force fixation member for valve 91 2007
2008/0071,368 Sinus-engaging valve fixation member 89 2007
2008/0071,369 Valve fixation member having engagement arms 77 2007
 
MEDTRONIC 3F THERAPEUTICS, INC. (6)
6,682,559 Prosthetic heart valve 260 2001
2004/0117,009 Prosthetic mitral valve 89 2003
6,911,043 Prosthetic heart value 125 2004
7,037,333 Prosthetic heart valve 82 2004
2006/0025,857 Implantable prosthetic valve 120 2005
2007/0173,932 PROSTHETIC MITRAL VALVE 27 2006
 
SULZER CARBOMEDICS INC. (6)
6,093,530 Non-calcific biomaterial by glutaraldehyde followed by oxidative fixation 50 1998
6,117,169 Living hinge attachment of leaflet to a valve body 51 1998
6,287,338 Pre-stressing devices incorporating materials subject to stress softening 34 1999
6,177,514 Blocked functional reagants for cross-linking biological tissues 51 1999
6,283,995 Heart valve leaflet with scalloped free margin 82 1999
6,478,819 Prosthetic heart valves with flexible post geometry 35 1999
 
COREVALVE, S.A. (5)
7,252,682 Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body 144 2002
7,018,406 Prosthetic valve for transluminal delivery 268 2003
2004/0210,304 Prosthetic valve for transluminal delivery 303 2004
2005/0033,398 Assembly for setting a valve prosthesis in a corporeal duct 212 2004
2006/0259,136 Heart valve prosthesis and methods of manufacture and use 147 2005
 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (5)
5,094,661 Calcification-resistant materials and methods of making same through use of trivalent aluminum 61 1988
5,368,608 Calcification-resistant materials and methods of making same through use of multivalent cations 61 1991
5,746,775 Method of making calcification-resistant bioprosthetic tissue 45 1993
5,679,112 Calcification-resistant materials and methods of making same through use of multivalent cations 37 1994
5,674,298 Calcification-resistant bioprosthetic tissue and methods of making same 66 1995
 
CRYOLIFE, INC. (4)
5,613,982 Method of preparing transplant tissue to reduce immunogenicity upon implantation 117 1995
5,632,778 Treated tissue for implantation and methods of preparation 96 1995
5,899,936 Treated tissue for implantation and methods of preparation 107 1995
7,318,998 Tissue decellularization 41 2003
 
MEDTRONIC AVE, INC. (4)
5,683,451 Apparatus and methods for deployment release of intraluminal prostheses 474 1995
5,824,041 Apparatus and methods for placement and repositioning of intraluminal prostheses 405 1996
6,126,685 Apparatus and methods for placement and repositioning of intraluminal prostheses 263 1998
6,350,278 Apparatus and methods for placement and repositioning of intraluminal prostheses 194 1999
 
OREGON HEALTH & SCIENCE UNIVERSITY (4)
7,452,371 Implantable vascular device 58 2001
2004/0186,558 Implantable vascular device 142 2003
2005/0143,807 Implantable vascular device comprising a bioabsorbable frame 130 2004
2006/0142,846 Implantable vascular device 58 2005
 
3F THERAPEUTICS, INC. (3)
6,872,226 Method of cutting material for use in implantable medical device 116 2002
2005/0049,692 Medical device for reduction of pressure effects of cardiac tricuspid valve regurgitation 175 2003
2005/0098,547 Method of cutting material for use in implantable medical device 41 2004
 
BIOSENSORS INTERNATIONAL GROUP, LTD. (3)
2003/0139,796 Endoprosthesis deployment system for treating vascular bifurcations 114 2002
2003/0139,803 Method of stenting a vessel with stent lumenal diameter increasing distally 74 2002
2005/0096,726 Noncylindrical stent deployment system for treating vascular bifurcations 118 2004
 
CLEMSON UNIVERSITY (3)
7,189,259 Tissue material and process for bioprosthesis 37 2003
2004/0153,145 Fixation method for bioprostheses 37 2003
2007/0005,132 Tissue material and process for bioprosthesis 24 2006
 
COOK BIOTECH INCORPORATED (3)
2004/0210,301 Implantable vascular device 117 2003
2006/0210,597 Prosthetic implants including ECM composite material 34 2006
2007/0050,014 Implantable valve 35 2006
 
EDWARDS LIFESCIENCES AG (3)
5,411,552 Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis 663 1994
5,840,081 System and method for implanting cardiac valves 498 1997
2003/0036,795 Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis 123 2002
 
HEARTPORT, INC. (3)
6,168,614 Valve prosthesis for implantation in the body 452 1998
6,425,916 Methods and devices for implanting cardiac valves 421 1999
6,582,462 Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis 209 2000
 
SORIN BIOMEDICA CARDIO S.P.A. (3)
5,713,953 Cardiac valve prosthesis particularly for replacement of the aortic valve 253 1996
6,379,740 Method for treating a prosthesis having an apertured structure and associated devices 25 1998
6,572,642 Method for treating a prosthesis having an apertured structure and associated devices 62 2002
 
ST. JUDE MEDICAL, INC. (3)
6,254,636 Single suture biological tissue aortic stentless valve 80 1998
6,471,723 Biocompatible prosthetic tissue 52 2000
6,558,417 Single suture biological tissue aortic stentless valve 32 2001
 
THE CHILDREN'S HOSPITAL OF PHILADELPHIA (3)
6,391,538 Stabilization of implantable bioprosthetic tissue 42 2000
6,861,211 Stabilization of implantable bioprosthetic devices 29 2001
6,824,970 Stabilization of implantable bioprosthetic tissue 26 2002
 
C.R. BARD, INC. (2)
6,077,297 Non-migrating vascular prosthesis and minimally invasive placement system therefor 251 1998
2004/0006,380 Stent delivery system 58 2002
 
Hancock Jaffe Laboratories (2)
5,595,571 Biological material pre-fixation treatment 84 1994
5,843,181 Biological material pre-fixation treatment 88 1997
 
MED INSTITUTE, INC. (2)
2007/0027,535 Implantable thromboresistant valve 33 2006
2007/0288,087 Artificial valve prosthesis 50 2007
 
PROVIDENCE HEALTH SYSTEM - OREGON (2)
7,163,556 Bioprosthesis and method for suturelessly making same 28 2002
7,322,932 Method for suturelessly attaching a biomaterial to an implantable bioprosthesis frame 44 2004
 
SADRA MEDICAL, INC. (2)
2005/0137,697 Leaflet engagement elements and methods for use thereof 139 2004
2005/0137,698 Leaflet engagement elements and methods for use thereof 122 2004
 
WILLIAM A. COOK AUSTRALIA PTY. LTD. (2)
2004/0073,289 Asymmetric stent graft attachment 51 2003
2004/0193,244 Device and method for treating thoracic aorta 26 2003
 
ABPS VENTURE ONE, LTD. (1)
2006/0167,543 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 133 2006
 
ADMEDUS REGEN PTY LTD (1)
2006/0193,885 Implantable biomaterial and a method of producing same 39 2005
 
AORTECH INTERNATIONAL PLC (1)
2006/0290,027 Heart valve prosthesis and method of manufacture 24 2006
 
BIOGENTIS INC. (1)
2003/0027,332 Tissue engineered heart valve 66 2002
 
Biomedical Design, Inc. (1)
6,521,179 Sterilization 28 2000
 
CELONOVA BIOSCIENCES, INC. (1)
2008/0086,205 Bioprosthetic Heart Valve With Polyphosphazene 25 2007
 
COLIBRI HEART VALVE LLC (1)
2005/0113,910 Percutaneously implantable replacement heart valve device and method of making same 181 2004
 
Dereume, Jean-Pierre G. E. (1)
6,241,738 Retrieval device for insertion into a body lumen 119 1998
 
ETHICON, INC. (1)
2003/0065,386 Radially expandable endoprosthesis device with two-stage deployment 97 2001
 
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (1)
2003/0149,476 Anchoring system for implantable heart valve prostheses 135 2002
 
GABBAY, SHLOMO (1)
5,935,163 Natural tissue heart valve prosthesis 93 1998
 
GI Dynamics, Inc. (1)
2005/0125,075 Intestinal sleeve 71 2004
 
GOLF TECH, LLC (1)
6,821,211 Sport swing analysis system 48 2001
 
JEN. CARIOTEC GMBH (1)
2007/0100,440 Device for the implantation and fixation of prosthetic valves 125 2006
 
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (1)
5,697,972 Bioprosthetic heart valves having high calcification resistance 48 1995
 
LEMAITRE ACQUISITION LLC (1)
6,183,481 Delivery system for self-expanding stents and grafts 95 1999
 
LIFESHIELD SCIENCES LLC (1)
2005/0143,804 Method and system for fixation of endoluminal devices 25 2005
 
Litana Ltd. (1)
5,876,434 Implantable medical devices of shape memory alloy 131 1997
 
LUCENT TECHNOLOGIES INC. (1)
5,841,382 Fast testing of D/A converters 39 1997
 
MEDTRONIC VASCULAR GALWAY LIMITED (1)
2003/0036,791 Implant implantation unit and procedure for implanting the unit 164 2002
 
MURES CARDIOVASCULAR RESEARCH, INC. (1)
6,214,055 Method and kit for rapid preparation of autologous tissue medical devices 58 1998
 
PERCUTANEOUS VALVE TECHNOLOGIES (1)
2008/0077,236 VALVE PROSTHESIS FOR IMPLANTATION IN BODY CHANNELS 24 2007
 
PFM MEDICAL AG (1)
2006/0224,183 Implantable device 25 2004
 
ROSS, DONALD D. (1)
5,352,240 Human heart valve replacement with porcine pulmonary valve 95 1989
 
Sadra Medical (1)
2005/0137,687 Heart valve anchor and method 151 2003
 
Sadra Medical, a Delaware Corporation (1)
* 2005/0137,688 Repositionable heart valve and method 258 2003
 
SORIN GROUP ITALIA S.R.L. (1)
2005/0197,695 Minimally-invasive cardiac-valve prosthesis 177 2005
 
SORIN GROUP USA, INC. (1)
6,613,086 Altering heart valve leaflet attachment geometry to influence the location and magnitude of maximum loaded stress on the leaflet 37 2000
 
SYMETIS SA (1)
2007/0213,813 Stent-valves for valve replacement and associated methods and systems for surgery 110 2006
 
TDK CORPORATION (1)
7,050,276 GMR magnetic sensing element having an antiferromagnetic layer extending beyond the track width and method for making the same 32 2003
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (1)
2002/0143,387 Stent repositioning and removal 73 2001
 
THE CLEVELAND CLINIC FOUNDATION (1)
2005/0119,728 Method for fixing tissue 24 2005
 
THE GENERAL HOSPITAL CORPORATION (1)
5,824,080 Photochemistry for the preparation of biologic grafts--allografts and xenografts 40 1996
 
UNIVERSITAT ZURICH (1)
2006/0246,584 In-vitro method for the production of a homologous stented tissue-engineered heart valve 31 2002
 
Wachauf, Gerhard (1)
7,014,655 Method for conserving biological prostheses, conserved biological prostheses and conserving solutions 26 2001
 
Other [Check patent profile for assignment information] (12)
5,332,402 Percutaneously-inserted cardiac valve 413 1992
* 6,120,534 Endoluminal prosthesis having adjustable constriction 129 1997
6,540,782 Artificial heart valve 58 2001
2002/0123,790 Enhanced engagement member for anchoring prosthetic devices in body lumen 79 2001
2002/0032,481 Heart valve prosthesis and sutureless implantation of a heart valve prosthesis 278 2001
6,821,297 Artificial heart valve, implantation instrument and method therefor 235 2002
2003/0040,792 Heart valve prosthesis and sutureless implantation of a heart valve prosthesis 178 2002
2004/0049,262 Stent valves and uses of same 182 2003
2005/0009,000 Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering 29 2004
* 2006/0064,151 Cranial aneurysm treatment arrangement 10 2005
2007/0020,248 Process for biological tissue 25 2006
2007/0123,700 Processes for removing cells and cell debris from tissue and tissue constructs used in transplantation and tissue reconstruction 24 2007
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
MIDDLE PEAK MEDICAL, INC. (2)
8,845,717 Coaptation enhancement implant, system, and method 0 2011
8,888,843 Device, system, and method for transcatheter treatment of valve regurgitation 0 2012
 
JENAVALVE TECHNOLOGY GMBH (1)
* 2014/0200,663 MEDICAL APPARATUS FOR THE THERAPEUTIC TREATMENT OF AN INSUFFICIENT CARDIAC VALVE 0 2014
 
MEDTRONIC, INC. (1)
* 2014/0277,419 Anti-Paravalvular Leakage Component for a Transcatheter Valve Prosthesis 0 2013
 
MITRAL TECH LTD. (1)
8,870,950 Rotation-based anchoring of an implant 0 2010
 
MITRALTECH LTD. (1)
* 8,852,272 Techniques for percutaneous mitral valve replacement and sealing 0 2012
* Cited By Examiner

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