US Patent No: 8,062,355 - Analytics, PDF, Full Text and PAIR Access

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Self-expandable medical instrument for treating defects in a patient's heart

ALSO PUBLISHED AS: 20070142906

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Abstract

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The invention relates to a self-expandable medical instrument (100) for treating defects in a patient's heart, in particular for the transvascular implantation of a prosthetic heart valve (30), wherein the medical instrument (100) is introducible into the body of a patient in a minimally-invasive procedure using a catheter system (40) and comprises a stent (1) made of a flexible mesh (2) of thin wires or filaments (2'). In order to realize a positioning of medical instrument (100) in the patient's heart which is as precise as possible and to securely anchor same there, it is provided for the stent (1) composed of the flexible mesh (2) to exhibit in the expanded state of the medical instrument (100) a distal retention area (10) with a laterally-inverted beaded portion (12) which is engageable in at least one pocket (51) of the patient's defective heart valve (50), a proximal retention area (20), and a center area (15) positioned between the distal and the proximal retention area (10, 20).

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
JENAVALVE TECHNOLOGY, INC.WILMINGTON, DE23

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ferrari, Markus Jena, DE 36 652
Figulla, Hans-Reiner Jena, DE 26 572

Cited Art Landscape

Patent Info (Count) # Cites Year
 
EDWARDS LIFESCIENCES CORPORATION (45)
5,061,277 Flexible cardiac valvular support prosthesis 289 1988
5,002,566 Calcification mitigation of bioprosthetic implants 64 1989
5,197,979 Stentless heart valve and holder 99 1990
5,104,407 Selectively flexible annuloplasty ring 239 1990
5,336,258 Stentless heart valve and holder 79 1992
5,549,666 Natural tissue valve prostheses having variably complaint leaflets 75 1994
5,928,281 Tissue heart valves 120 1997
5,880,242 Nonpolymeric epoxy compounds for cross linking biological tissue and bioprosthetic grafts prepared thereby 25 1997
6,001,126 Stentless bioprosthetic heart valve with coronary protuberances and related methods for surgical repair of defective heart valves 61 1997
6,102,944 Methods of tissue heart valve assembly 123 1999
6,231,602 Aortic annuloplasty ring 145 1999
6,558,418 Flexible heart valve 100 1999
6,342,070 Stentless bioprosthetic heart valve with patent coronary protuberances and method of surgical use thereof 55 1999
6,338,740 Flexible heart valve leaflets 121 2000
6,344,044 Apparatus and methods for delivery of intraluminal prosthesis 56 2000
6,454,799 Minimally-invasive heart valves and methods of use 278 2000
6,585,766 Cloth-covered stents for tissue heart valves 73 2000
6,808,529 Apparatus and methods for delivery of intraluminal prostheses 54 2001
6,736,845 Holder for flexible heart valve 106 2001
2003/0050,694 Methods and apparatuses for deploying minimally-invasive heart valves 185 2001
7,141,064 Compressed tissue for heart valve leaflets 40 2002
6,767,362 Minimally-invasive heart valves and methods of use 188 2002
7,399,315 Minimally-invasive heart valve with cusp positioners 64 2003
6,945,997 Heart valves and suture rings therefor 86 2003
7,137,184 Continuous heart valve support frame and method of manufacture 56 2003
2004/0148,018 Flexible heart valve and associated connecting band 84 2003
7,381,218 System and method for implanting a two-part prosthetic heart valve 95 2004
7,318,278 Method of manufacture of a heart valve support frame 23 2005
2006/0293,745 Anatomically approximate prosthetic mitral heart valve 27 2005
2006/0229,719 Highly flexible heart valve connecting band 35 2005
2007/0005,131 Heart valve delivery system 96 2005
2006/0009,842 Contoured heart valve suture rings 66 2005
2007/0088,431 Heart valve delivery system with valve catheter 143 2005
2007/0112,422 Transapical heart valve delivery system and method 104 2005
2006/0229,718 Stress absorbing flexible heart valve frame 21 2006
7,473,275 Stress absorbing flexible heart valve frame 24 2006
2007/0244,551 Holders for prosthetic aortic heart valves 22 2006
2006/0287,717 Methods for rapid deployment of prosthetic heart valves 63 2006
2006/0287,719 Rapid deployment prosthetic heart valve 49 2006
2007/0123,979 Apparatus, system, and method for treatment of posterior leaflet prolapse 31 2006
2008/0021,546 System for deploying balloon-expandable heart valves 37 2006
2008/0154,355 Implantable prosthetic valve assembly and method of making the same 84 2006
2008/0065,011 INTEGRATED HEART VALVE DELIVERY SYSTEM 81 2007
2008/0102,439 BIOLOGICAL TISSUE FOR SURGICAL IMPLANTATION 23 2007
2008/0269,878 MINIMALLY-INVASIVE HEART VALVE WITH CUSP POSITIONERS 85 2008
 
COOK MEDICAL TECHNOLOGIES LLC (17)
6,200,336 Multiple-sided intraluminal medical device 287 1999
6,508,833 Multiple-sided intraluminal medical device 282 2001
6,974,474 Multiple-sided intraluminal medical device 125 2002
7,081,132 Flexible barb for anchoring a prosthesis 62 2003
2004/0117,004 Stent and method of forming a stent with integral barbs 177 2003
2007/0260,327 Artificial Valve Prosthesis with Improved Flow Dynamics 48 2004
2004/0260,389 Artificial valve prosthesis with improved flow dynamics 183 2004
2005/0222,668 Flareable branch vessel prosthesis and method 67 2004
2006/0111,770 Implantable vascular device comprising a bioabsorbable frame 24 2005
2007/0021,826 Intralumenally implantable frames 27 2006
2007/0038,291 Intralumenally-implantable frames 31 2006
2007/0093,887 Artificial valve with center leaflet attachment 39 2006
2007/0100,435 Artificial prostheses with preferred geometries 59 2006
2007/0162,103 Implantable device with remodelable material and covering material 76 2006
2008/0033,534 Flexible Barb for Anchoring a Prosthesis 28 2007
2008/0097,586 IMPLANTABLE VASCULAR DEVICE 22 2007
2008/0200,977 Artificial Valve Prostheses with a Free Leaflet Portion 21 2008
 
COOK INCORPORATED (11)
5,035,706 Percutaneous stent and method for retrieval thereof 581 1989
5,456,713 Expandable transluminal graft prosthesis for repairs of aneurysm and method for implanting 334 1993
5,755,777 Expandable transluminal graft prosthesis for repair of aneurysm 153 1996
2005/0096,736 Percutaneous heart valve devices 121 2004
2005/0149,166 Branch vessel prosthesis with anchoring device and method 57 2004
2005/0171,597 Helical stent for branched vessel prosthesis 45 2004
2005/0171,598 Aorta and branch vessel stent grafts and method 63 2004
2006/0058,864 Balloon flareable branch vessel prosthesis and method 48 2004
2007/0179,592 Branch vessel prosthesis with positional indicator system and method 54 2004
2005/0267,560 Implantable bioabsorbable valve support frame 112 2005
2007/0038,295 Artificial valve prosthesis having a ring frame 63 2006
 
EDWARDS LIFESCIENCES PVT, INC. (8)
6,893,460 Implantable prosthetic valve 236 2001
6,908,481 Value prosthesis for implantation in body channels 243 2002
6,730,118 Implantable prosthetic valve 289 2002
2004/0039,436 Implantable prosthetic valve 210 2003
2005/0075,725 Implantable prosthetic valve with non-laminar flow 87 2003
7,393,360 Implantable prosthetic valve 71 2005
2008/0004,688 IMPLANTABLE PROSTHETIC VALVE 29 2007
2008/0275,549 IMPLANTABLE PROSTHETIC VALVE WITH NON-LAMINAR FLOW 22 2008
 
MEDTRONIC COREVALVE LLC (8)
6,830,584 Device for replacing a cardiac valve by percutaneous route 181 2002
7,329,278 Prosthetic valve for transluminal delivery 85 2006
2006/0265,056 Heart valve prosthesis and methods of manufacture and use 130 2006
2007/0043,435 Non-cylindrical prosthetic valve system for transluminal delivery 141 2006
2007/0239,271 Systems and methods for loading a prosthesis onto a minimally invasive delivery system 58 2006
2008/0215,143 ASSEMBLY FOR PLACING A PROSTHETIC VALVE IN A DUCT IN THE BODY 74 2007
2008/0140,189 SYSTEM AND METHOD FOR TRANSAPICAL DELIVERY OF AN ANNULUS ANCHORED SELF-EXPANDING VALVE 104 2007
2008/0133,003 PROSTHETIC VALVE FOR TRANSLUMINAL DELIVERY 74 2008
 
MEDTRONIC, INC. (8)
5,279,612 Dynamic fixation of porcine aortic valves 48 1991
5,509,930 Stentless heart valve 57 1993
6,509,145 Process for reducing mineralization of tissue used in transplantation 38 2001
6,790,230 Vascular implant 159 2002
7,078,163 Process for reducing mineralization of tissue used in transplantation 32 2002
2005/0119,736 Bioprosthetic tissue preparation with synthetic hydrogels 30 2004
7,238,200 Apparatus and methods for making leaflets and valve prostheses including such leaflets 50 2005
2007/0203,576 APPARATUS AND METHODS FOR MAKING LEAFLETS AND VALVE PROSTHESES INCLUDING SUCH LEAFLETS 49 2007
 
JENAVALVE TECHNOLOGY, INC. (7)
6,254,564 Left ventricular conduit with blood vessel graft 80 1999
7,198,646 Device for fastening and anchoring cardiac valve prostheses 80 2001
6,881,199 Left ventricular conduit with blood vessel graft 58 2001
2005/0033,220 Left ventricular conduit with blood vessel graft 27 2004
2007/0005,129 Anchoring system for implantable heart valve prostheses 105 2006
2007/0142,906 Self-expandable medical instrument for treating defects in a patient's heart 60 2006
2008/0262,602 Methods and conduits for flowing blood from a heart chamber to a blood vessel 37 2008
 
MEDTRONIC VENTOR TECHNOLOGIES LTD. (7)
7,201,772 Fluid flow prosthetic device 165 2004
2008/0071,361 Leaflet-sensitive valve fixation member 91 2007
2008/0071,362 Valve prosthesis implantation techniques 78 2007
2008/0071,363 Valve prosthesis fixation techniques using sandwiching 93 2007
2008/0071,366 Axial-force fixation member for valve 76 2007
2008/0071,368 Sinus-engaging valve fixation member 76 2007
2008/0071,369 Valve fixation member having engagement arms 55 2007
 
MEDTRONIC 3F THERAPEUTICS, INC. (6)
6,682,559 Prosthetic heart valve 232 2001
2004/0117,009 Prosthetic mitral valve 78 2003
6,911,043 Prosthetic heart value 108 2004
7,037,333 Prosthetic heart valve 71 2004
2006/0025,857 Implantable prosthetic valve 106 2005
2007/0173,932 PROSTHETIC MITRAL VALVE 23 2006
 
SULZER CARBOMEDICS INC. (6)
6,093,530 Non-calcific biomaterial by glutaraldehyde followed by oxidative fixation 45 1998
6,117,169 Living hinge attachment of leaflet to a valve body 45 1998
6,287,338 Pre-stressing devices incorporating materials subject to stress softening 29 1999
6,177,514 Blocked functional reagants for cross-linking biological tissues 44 1999
6,283,995 Heart valve leaflet with scalloped free margin 75 1999
6,478,819 Prosthetic heart valves with flexible post geometry 31 1999
 
COREVALVE, S.A. (5)
7,252,682 Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body 126 2002
7,018,406 Prosthetic valve for transluminal delivery 225 2003
2004/0210,304 Prosthetic valve for transluminal delivery 266 2004
2005/0033,398 Assembly for setting a valve prosthesis in a corporeal duct 186 2004
2006/0259,136 Heart valve prosthesis and methods of manufacture and use 120 2005
 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (5)
5,094,661 Calcification-resistant materials and methods of making same through use of trivalent aluminum 52 1988
5,368,608 Calcification-resistant materials and methods of making same through use of multivalent cations 52 1991
5,746,775 Method of making calcification-resistant bioprosthetic tissue 38 1993
5,679,112 Calcification-resistant materials and methods of making same through use of multivalent cations 32 1994
5,674,298 Calcification-resistant bioprosthetic tissue and methods of making same 58 1995
 
CRYOLIFE, INC. (4)
5,613,982 Method of preparing transplant tissue to reduce immunogenicity upon implantation 110 1995
5,632,778 Treated tissue for implantation and methods of preparation 90 1995
5,899,936 Treated tissue for implantation and methods of preparation 98 1995
7,318,998 Tissue decellularization 33 2003
 
MEDTRONIC AVE, INC. (4)
5,683,451 Apparatus and methods for deployment release of intraluminal prostheses 439 1995
5,824,041 Apparatus and methods for placement and repositioning of intraluminal prostheses 354 1996
6,126,685 Apparatus and methods for placement and repositioning of intraluminal prostheses 238 1998
6,350,278 Apparatus and methods for placement and repositioning of intraluminal prostheses 173 1999
 
OREGON HEALTH & SCIENCE UNIVERSITY (4)
7,452,371 Implantable vascular device 52 2001
2004/0186,558 Implantable vascular device 126 2003
2005/0143,807 Implantable vascular device comprising a bioabsorbable frame 111 2004
2006/0142,846 Implantable vascular device 52 2005
 
3F THERAPEUTICS, INC. (3)
6,872,226 Method of cutting material for use in implantable medical device 102 2002
2005/0049,692 Medical device for reduction of pressure effects of cardiac tricuspid valve regurgitation 152 2003
2005/0098,547 Method of cutting material for use in implantable medical device 37 2004
 
BIOSENSORS INTERNATIONAL GROUP, LTD. (3)
2003/0139,796 Endoprosthesis deployment system for treating vascular bifurcations 102 2002
2003/0139,803 Method of stenting a vessel with stent lumenal diameter increasing distally 66 2002
2005/0096,726 Noncylindrical stent deployment system for treating vascular bifurcations 107 2004
 
CLEMSON UNIVERSITY (3)
2004/0153,145 Fixation method for bioprostheses 33 2003
7,189,259 Tissue material and process for bioprosthesis 30 2003
2007/0005,132 Tissue material and process for bioprosthesis 21 2006
 
COOK BIOTECH INCORPORATED (3)
2004/0210,301 Implantable vascular device 106 2003
2006/0210,597 Prosthetic implants including ECM composite material 30 2006
2007/0050,014 Implantable valve 28 2006
 
EDWARDS LIFESCIENCES AG (3)
5,411,552 Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis 608 1994
5,840,081 System and method for implanting cardiac valves 456 1997
2003/0036,795 Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis 110 2002
 
HEARTPORT, INC. (3)
6,168,614 Valve prosthesis for implantation in the body 411 1998
6,425,916 Methods and devices for implanting cardiac valves 380 1999
6,582,462 Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis 186 2000
 
SORIN BIOMEDICA CARDIO S.P.A. (3)
5,713,953 Cardiac valve prosthesis particularly for replacement of the aortic valve 228 1996
6,379,740 Method for treating a prosthesis having an apertured structure and associated devices 22 1998
6,572,642 Method for treating a prosthesis having an apertured structure and associated devices 58 2002
 
ST. JUDE MEDICAL, INC. (3)
6,254,636 Single suture biological tissue aortic stentless valve 73 1998
6,471,723 Biocompatible prosthetic tissue 44 2000
6,558,417 Single suture biological tissue aortic stentless valve 29 2001
 
THE CHILDREN'S HOSPITAL OF PHILADELPHIA (3)
6,391,538 Stabilization of implantable bioprosthetic tissue 36 2000
6,861,211 Stabilization of implantable bioprosthetic devices 25 2001
6,824,970 Stabilization of implantable bioprosthetic tissue 23 2002
 
C.R. BARD, INC. (2)
6,077,297 Non-migrating vascular prosthesis and minimally invasive placement system therefor 228 1998
2004/0006,380 Stent delivery system 52 2002
 
Hancock Jaffe Laboratories (2)
5,595,571 Biological material pre-fixation treatment 76 1994
5,843,181 Biological material pre-fixation treatment 80 1997
 
MED INSTITUTE, INC. (2)
2007/0027,535 Implantable thromboresistant valve 29 2006
2007/0288,087 Artificial valve prosthesis 44 2007
 
PROVIDENCE HEALTH SYSTEM - OREGON (2)
7,163,556 Bioprosthesis and method for suturelessly making same 25 2002
7,322,932 Method for suturelessly attaching a biomaterial to an implantable bioprosthesis frame 36 2004
 
SADRA MEDICAL, INC. (2)
2005/0137,697 Leaflet engagement elements and methods for use thereof 115 2004
2005/0137,698 Leaflet engagement elements and methods for use thereof 103 2004
 
WILLIAM A. COOK AUSTRALIA PTY. LTD. (2)
2004/0073,289 Asymmetric stent graft attachment 48 2003
2004/0193,244 Device and method for treating thoracic aorta 23 2003
 
ABPS VENTURE ONE, LTD. (1)
2006/0167,543 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 118 2006
 
ADMEDUS REGEN PTY LTD (1)
2006/0193,885 Implantable biomaterial and a method of producing same 32 2005
 
AORTECH INTERNATIONAL PLC (1)
2006/0290,027 Heart valve prosthesis and method of manufacture 21 2006
 
BIOGENTIS INC. (1)
2003/0027,332 Tissue engineered heart valve 59 2002
 
Biomedical Design, Inc. (1)
6,521,179 Sterilization 25 2000
 
CELONOVA BIOSCIENCES, INC. (1)
2008/0086,205 Bioprosthetic Heart Valve With Polyphosphazene 22 2007
 
COLIBRI HEART VALVE LLC (1)
2005/0113,910 Percutaneously implantable replacement heart valve device and method of making same 157 2004
 
Dereume, Jean-Pierre G. E. (1)
6,241,738 Retrieval device for insertion into a body lumen 112 1998
 
ETHICON, INC. (1)
2003/0065,386 Radially expandable endoprosthesis device with two-stage deployment 83 2001
 
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (1)
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GABBAY, SHLOMO (1)
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GI Dynamics, Inc. (1)
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GOLF TECH, LLC (1)
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JEN. CARIOTEC GMBH (1)
2007/0100,440 Device for the implantation and fixation of prosthetic valves 108 2006
 
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (1)
5,697,972 Bioprosthetic heart valves having high calcification resistance 43 1995
 
LEMAITRE ACQUISITION LLC (1)
6,183,481 Delivery system for self-expanding stents and grafts 84 1999
 
LIFESHIELD SCIENCES LLC (1)
2005/0143,804 Method and system for fixation of endoluminal devices 21 2005
 
Litana Ltd. (1)
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LUCENT TECHNOLOGIES INC. (1)
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MEDTRONIC VASCULAR GALWAY LIMITED (1)
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PERCUTANEOUS VALVE TECHNOLOGIES (1)
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PFM MEDICAL AG (1)
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ROSS, DONALD D. (1)
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Sadra Medical (1)
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Sadra Medical, a Delaware Corporation (1)
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SORIN GROUP ITALIA S.R.L. (1)
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SORIN GROUP USA, INC. (1)
6,613,086 Altering heart valve leaflet attachment geometry to influence the location and magnitude of maximum loaded stress on the leaflet 34 2000
 
SYMETIS SA (1)
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TDK CORPORATION (1)
7,050,276 GMR magnetic sensing element having an antiferromagnetic layer extending beyond the track width and method for making the same 29 2003
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (1)
2002/0143,387 Stent repositioning and removal 63 2001
 
THE CLEVELAND CLINIC FOUNDATION (1)
2005/0119,728 Method for fixing tissue 21 2005
 
THE GENERAL HOSPITAL CORPORATION (1)
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UNIVERSITAT ZURICH (1)
2006/0246,584 In-vitro method for the production of a homologous stented tissue-engineered heart valve 26 2002
 
Wachauf, Gerhard (1)
7,014,655 Method for conserving biological prostheses, conserved biological prostheses and conserving solutions 22 2001
 
Other [Check patent profile for assignment information] (12)
5,332,402 Percutaneously-inserted cardiac valve 376 1992
6,120,534 Endoluminal prosthesis having adjustable constriction 112 1997
6,540,782 Artificial heart valve 47 2001
2002/0123,790 Enhanced engagement member for anchoring prosthetic devices in body lumen 72 2001
2002/0032,481 Heart valve prosthesis and sutureless implantation of a heart valve prosthesis 244 2001
6,821,297 Artificial heart valve, implantation instrument and method therefor 207 2002
2003/0040,792 Heart valve prosthesis and sutureless implantation of a heart valve prosthesis 155 2002
2004/0049,262 Stent valves and uses of same 155 2003
2005/0009,000 Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering 23 2004
2006/0064,151 Cranial aneurysm treatment arrangement 8 2005
2007/0020,248 Process for biological tissue 21 2006
2007/0123,700 Processes for removing cells and cell debris from tissue and tissue constructs used in transplantation and tissue reconstruction 21 2007

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