US Patent No: 8,062,355 - Analytics, PDF, Full Text and PAIR Access

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Self-expandable medical instrument for treating defects in a patient's heart

ALSO PUBLISHED AS: 20070142906
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Abstract

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The invention relates to a self-expandable medical instrument (100) for treating defects in a patient's heart, in particular for the transvascular implantation of a prosthetic heart valve (30), wherein the medical instrument (100) is introducible into the body of a patient in a minimally-invasive procedure using a catheter system (40) and comprises a stent (1) made of a flexible mesh (2) of thin wires or filaments (2'). In order to realize a positioning of medical instrument (100) in the patient's heart which is as precise as possible and to securely anchor same there, it is provided for the stent (1) composed of the flexible mesh (2) to exhibit in the expanded state of the medical instrument (100) a distal retention area (10) with a laterally-inverted beaded portion (12) which is engageable in at least one pocket (51) of the patient's defective heart valve (50), a proximal retention area (20), and a center area (15) positioned between the distal and the proximal retention area (10, 20).

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
JENAVALVE TECHNOLOGY, INC.WILMINGTON, DE22

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ferrari, Markus Jena, DE 41 743
Figulla, Hans-Reiner Jena, DE 30 678

Cited Art Landscape

Patent Info (Count) # Cites Year
 
EDWARDS LIFESCIENCES CORPORATION (45)
5,061,277 Flexible cardiac valvular support prosthesis 302 1988
5,002,566 Calcification mitigation of bioprosthetic implants 68 1989
5,197,979 Stentless heart valve and holder 102 1990
5,104,407 Selectively flexible annuloplasty ring 248 1990
5,336,258 Stentless heart valve and holder 87 1992
5,549,666 Natural tissue valve prostheses having variably complaint leaflets 81 1994
5,928,281 Tissue heart valves 124 1997
5,880,242 Nonpolymeric epoxy compounds for cross linking biological tissue and bioprosthetic grafts prepared thereby 28 1997
6,001,126 Stentless bioprosthetic heart valve with coronary protuberances and related methods for surgical repair of defective heart valves 64 1997
6,102,944 Methods of tissue heart valve assembly 129 1999
6,231,602 Aortic annuloplasty ring 155 1999
6,558,418 Flexible heart valve 109 1999
6,342,070 Stentless bioprosthetic heart valve with patent coronary protuberances and method of surgical use thereof 58 1999
6,338,740 Flexible heart valve leaflets 126 2000
6,344,044 Apparatus and methods for delivery of intraluminal prosthesis 61 2000
6,454,799 Minimally-invasive heart valves and methods of use 302 2000
6,585,766 Cloth-covered stents for tissue heart valves 79 2000
6,808,529 Apparatus and methods for delivery of intraluminal prostheses 58 2001
6,736,845 Holder for flexible heart valve 113 2001
2003/0050,694 Methods and apparatuses for deploying minimally-invasive heart valves 207 2001
7,141,064 Compressed tissue for heart valve leaflets 45 2002
6,767,362 Minimally-invasive heart valves and methods of use 203 2002
7,399,315 Minimally-invasive heart valve with cusp positioners 74 2003
6,945,997 Heart valves and suture rings therefor 91 2003
7,137,184 Continuous heart valve support frame and method of manufacture 64 2003
2004/0148,018 Flexible heart valve and associated connecting band 92 2003
7,381,218 System and method for implanting a two-part prosthetic heart valve 109 2004
7,318,278 Method of manufacture of a heart valve support frame 27 2005
2006/0293,745 Anatomically approximate prosthetic mitral heart valve 30 2005
2006/0229,719 Highly flexible heart valve connecting band 40 2005
2007/0005,131 Heart valve delivery system 106 2005
2006/0009,842 Contoured heart valve suture rings 70 2005
2007/0088,431 Heart valve delivery system with valve catheter 160 2005
2007/0112,422 Transapical heart valve delivery system and method 125 2005
2006/0229,718 Stress absorbing flexible heart valve frame 24 2006
7,473,275 Stress absorbing flexible heart valve frame 27 2006
2007/0244,551 Holders for prosthetic aortic heart valves 25 2006
2006/0287,717 Methods for rapid deployment of prosthetic heart valves 73 2006
2006/0287,719 Rapid deployment prosthetic heart valve 55 2006
2007/0123,979 Apparatus, system, and method for treatment of posterior leaflet prolapse 34 2006
2008/0021,546 System for deploying balloon-expandable heart valves 43 2006
2008/0154,355 Implantable prosthetic valve assembly and method of making the same 97 2006
2008/0065,011 INTEGRATED HEART VALVE DELIVERY SYSTEM 89 2007
2008/0102,439 BIOLOGICAL TISSUE FOR SURGICAL IMPLANTATION 28 2007
2008/0269,878 MINIMALLY-INVASIVE HEART VALVE WITH CUSP POSITIONERS 99 2008
 
COOK MEDICAL TECHNOLOGIES LLC (18)
6,200,336 Multiple-sided intraluminal medical device 310 1999
6,508,833 Multiple-sided intraluminal medical device 303 2001
6,974,474 Multiple-sided intraluminal medical device 137 2002
7,081,132 Flexible barb for anchoring a prosthesis 70 2003
2004/0117,004 Stent and method of forming a stent with integral barbs 198 2003
2007/0260,327 Artificial Valve Prosthesis with Improved Flow Dynamics 53 2004
2004/0260,389 Artificial valve prosthesis with improved flow dynamics 199 2004
2005/0222,668 Flareable branch vessel prosthesis and method 75 2004
2006/0058,864 Balloon flareable branch vessel prosthesis and method 55 2004
2006/0111,770 Implantable vascular device comprising a bioabsorbable frame 27 2005
2007/0021,826 Intralumenally implantable frames 30 2006
2007/0038,291 Intralumenally-implantable frames 34 2006
2007/0093,887 Artificial valve with center leaflet attachment 45 2006
2007/0100,435 Artificial prostheses with preferred geometries 71 2006
2007/0162,103 Implantable device with remodelable material and covering material 83 2006
2008/0033,534 Flexible Barb for Anchoring a Prosthesis 32 2007
2008/0097,586 IMPLANTABLE VASCULAR DEVICE 25 2007
2008/0200,977 Artificial Valve Prostheses with a Free Leaflet Portion 25 2008
 
COOK INCORPORATED (10)
5,035,706 Percutaneous stent and method for retrieval thereof 598 1989
5,456,713 Expandable transluminal graft prosthesis for repairs of aneurysm and method for implanting 349 1993
5,755,777 Expandable transluminal graft prosthesis for repair of aneurysm 163 1996
2005/0096,736 Percutaneous heart valve devices 135 2004
2005/0149,166 Branch vessel prosthesis with anchoring device and method 63 2004
2005/0171,597 Helical stent for branched vessel prosthesis 50 2004
2005/0171,598 Aorta and branch vessel stent grafts and method 74 2004
2007/0179,592 Branch vessel prosthesis with positional indicator system and method 58 2004
2005/0267,560 Implantable bioabsorbable valve support frame 123 2005
2007/0038,295 Artificial valve prosthesis having a ring frame 73 2006
 
EDWARDS LIFESCIENCES PVT, INC. (8)
6,893,460 Implantable prosthetic valve 262 2001
6,908,481 Value prosthesis for implantation in body channels 269 2002
6,730,118 Implantable prosthetic valve 318 2002
2004/0039,436 Implantable prosthetic valve 230 2003
2005/0075,725 Implantable prosthetic valve with non-laminar flow 92 2003
7,393,360 Implantable prosthetic valve 82 2005
2008/0004,688 IMPLANTABLE PROSTHETIC VALVE 36 2007
2008/0275,549 IMPLANTABLE PROSTHETIC VALVE WITH NON-LAMINAR FLOW 26 2008
 
MEDTRONIC COREVALVE LLC (8)
6,830,584 Device for replacing a cardiac valve by percutaneous route 199 2002
7,329,278 Prosthetic valve for transluminal delivery 95 2006
2006/0265,056 Heart valve prosthesis and methods of manufacture and use 146 2006
2007/0043,435 Non-cylindrical prosthetic valve system for transluminal delivery 159 2006
2007/0239,271 Systems and methods for loading a prosthesis onto a minimally invasive delivery system 68 2006
2008/0215,143 ASSEMBLY FOR PLACING A PROSTHETIC VALVE IN A DUCT IN THE BODY 82 2007
2008/0140,189 SYSTEM AND METHOD FOR TRANSAPICAL DELIVERY OF AN ANNULUS ANCHORED SELF-EXPANDING VALVE 118 2007
2008/0133,003 PROSTHETIC VALVE FOR TRANSLUMINAL DELIVERY 80 2008
 
MEDTRONIC, INC. (8)
5,279,612 Dynamic fixation of porcine aortic valves 53 1991
5,509,930 Stentless heart valve 62 1993
6,509,145 Process for reducing mineralization of tissue used in transplantation 42 2001
6,790,230 Vascular implant 178 2002
7,078,163 Process for reducing mineralization of tissue used in transplantation 36 2002
2005/0119,736 Bioprosthetic tissue preparation with synthetic hydrogels 34 2004
7,238,200 Apparatus and methods for making leaflets and valve prostheses including such leaflets 56 2005
2007/0203,576 APPARATUS AND METHODS FOR MAKING LEAFLETS AND VALVE PROSTHESES INCLUDING SUCH LEAFLETS 55 2007
 
JENAVALVE TECHNOLOGY, INC. (7)
6,254,564 Left ventricular conduit with blood vessel graft 85 1999
7,198,646 Device for fastening and anchoring cardiac valve prostheses 90 2001
6,881,199 Left ventricular conduit with blood vessel graft 62 2001
2005/0033,220 Left ventricular conduit with blood vessel graft 30 2004
2007/0005,129 Anchoring system for implantable heart valve prostheses 115 2006
2007/0142,906 Self-expandable medical instrument for treating defects in a patient's heart 66 2006
2008/0262,602 Methods and conduits for flowing blood from a heart chamber to a blood vessel 43 2008
 
MEDTRONIC VENTOR TECHNOLOGIES LTD. (7)
7,201,772 Fluid flow prosthetic device 184 2004
2008/0071,361 Leaflet-sensitive valve fixation member 100 2007
2008/0071,362 Valve prosthesis implantation techniques 86 2007
2008/0071,363 Valve prosthesis fixation techniques using sandwiching 108 2007
2008/0071,366 Axial-force fixation member for valve 86 2007
2008/0071,368 Sinus-engaging valve fixation member 84 2007
2008/0071,369 Valve fixation member having engagement arms 69 2007
 
MEDTRONIC 3F THERAPEUTICS, INC. (6)
6,682,559 Prosthetic heart valve 251 2001
2004/0117,009 Prosthetic mitral valve 86 2003
6,911,043 Prosthetic heart value 120 2004
7,037,333 Prosthetic heart valve 79 2004
2006/0025,857 Implantable prosthetic valve 115 2005
2007/0173,932 PROSTHETIC MITRAL VALVE 27 2006
 
SULZER CARBOMEDICS INC. (6)
6,093,530 Non-calcific biomaterial by glutaraldehyde followed by oxidative fixation 49 1998
6,117,169 Living hinge attachment of leaflet to a valve body 50 1998
6,287,338 Pre-stressing devices incorporating materials subject to stress softening 33 1999
6,177,514 Blocked functional reagants for cross-linking biological tissues 49 1999
6,283,995 Heart valve leaflet with scalloped free margin 80 1999
6,478,819 Prosthetic heart valves with flexible post geometry 34 1999
 
COREVALVE, S.A. (5)
7,252,682 Kit enabling a prosthetic valve to be placed in a body enabling a prosthetic valve to be put into place in a duct in the body 137 2002
7,018,406 Prosthetic valve for transluminal delivery 252 2003
2004/0210,304 Prosthetic valve for transluminal delivery 290 2004
2005/0033,398 Assembly for setting a valve prosthesis in a corporeal duct 203 2004
2006/0259,136 Heart valve prosthesis and methods of manufacture and use 137 2005
 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (5)
5,094,661 Calcification-resistant materials and methods of making same through use of trivalent aluminum 57 1988
5,368,608 Calcification-resistant materials and methods of making same through use of multivalent cations 57 1991
5,746,775 Method of making calcification-resistant bioprosthetic tissue 43 1993
5,679,112 Calcification-resistant materials and methods of making same through use of multivalent cations 36 1994
5,674,298 Calcification-resistant bioprosthetic tissue and methods of making same 62 1995
 
CRYOLIFE, INC. (4)
5,613,982 Method of preparing transplant tissue to reduce immunogenicity upon implantation 116 1995
5,632,778 Treated tissue for implantation and methods of preparation 95 1995
5,899,936 Treated tissue for implantation and methods of preparation 104 1995
7,318,998 Tissue decellularization 38 2003
 
MEDTRONIC AVE, INC. (4)
5,683,451 Apparatus and methods for deployment release of intraluminal prostheses 461 1995
5,824,041 Apparatus and methods for placement and repositioning of intraluminal prostheses 385 1996
6,126,685 Apparatus and methods for placement and repositioning of intraluminal prostheses 256 1998
6,350,278 Apparatus and methods for placement and repositioning of intraluminal prostheses 184 1999
 
OREGON HEALTH & SCIENCE UNIVERSITY (4)
7,452,371 Implantable vascular device 58 2001
2004/0186,558 Implantable vascular device 139 2003
2005/0143,807 Implantable vascular device comprising a bioabsorbable frame 126 2004
2006/0142,846 Implantable vascular device 57 2005
 
3F THERAPEUTICS, INC. (3)
6,872,226 Method of cutting material for use in implantable medical device 114 2002
2005/0049,692 Medical device for reduction of pressure effects of cardiac tricuspid valve regurgitation 168 2003
2005/0098,547 Method of cutting material for use in implantable medical device 41 2004
 
BIOSENSORS INTERNATIONAL GROUP, LTD. (3)
2003/0139,796 Endoprosthesis deployment system for treating vascular bifurcations 111 2002
2003/0139,803 Method of stenting a vessel with stent lumenal diameter increasing distally 72 2002
2005/0096,726 Noncylindrical stent deployment system for treating vascular bifurcations 116 2004
 
CLEMSON UNIVERSITY (3)
2004/0153,145 Fixation method for bioprostheses 36 2003
7,189,259 Tissue material and process for bioprosthesis 36 2003
2007/0005,132 Tissue material and process for bioprosthesis 24 2006
 
COOK BIOTECH INCORPORATED (3)
2004/0210,301 Implantable vascular device 115 2003
2006/0210,597 Prosthetic implants including ECM composite material 34 2006
2007/0050,014 Implantable valve 33 2006
 
EDWARDS LIFESCIENCES AG (3)
5,411,552 Valve prothesis for implantation in the body and a catheter for implanting such valve prothesis 642 1994
5,840,081 System and method for implanting cardiac valves 481 1997
2003/0036,795 Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis 120 2002
 
HEARTPORT, INC. (3)
6,168,614 Valve prosthesis for implantation in the body 436 1998
6,425,916 Methods and devices for implanting cardiac valves 408 1999
6,582,462 Valve prosthesis for implantation in the body and a catheter for implanting such valve prosthesis 200 2000
 
SORIN BIOMEDICA CARDIO S.P.A. (3)
5,713,953 Cardiac valve prosthesis particularly for replacement of the aortic valve 246 1996
6,379,740 Method for treating a prosthesis having an apertured structure and associated devices 25 1998
6,572,642 Method for treating a prosthesis having an apertured structure and associated devices 62 2002
 
ST. JUDE MEDICAL, INC. (3)
6,254,636 Single suture biological tissue aortic stentless valve 79 1998
6,471,723 Biocompatible prosthetic tissue 49 2000
6,558,417 Single suture biological tissue aortic stentless valve 32 2001
 
THE CHILDREN'S HOSPITAL OF PHILADELPHIA (3)
6,391,538 Stabilization of implantable bioprosthetic tissue 40 2000
6,861,211 Stabilization of implantable bioprosthetic devices 28 2001
6,824,970 Stabilization of implantable bioprosthetic tissue 26 2002
 
C.R. BARD, INC. (2)
6,077,297 Non-migrating vascular prosthesis and minimally invasive placement system therefor 243 1998
2004/0006,380 Stent delivery system 57 2002
 
Hancock Jaffe Laboratories (2)
5,595,571 Biological material pre-fixation treatment 81 1994
5,843,181 Biological material pre-fixation treatment 84 1997
 
MED INSTITUTE, INC. (2)
2007/0027,535 Implantable thromboresistant valve 32 2006
2007/0288,087 Artificial valve prosthesis 50 2007
 
PROVIDENCE HEALTH SYSTEM - OREGON (2)
7,163,556 Bioprosthesis and method for suturelessly making same 28 2002
7,322,932 Method for suturelessly attaching a biomaterial to an implantable bioprosthesis frame 43 2004
 
SADRA MEDICAL, INC. (2)
2005/0137,697 Leaflet engagement elements and methods for use thereof 132 2004
2005/0137,698 Leaflet engagement elements and methods for use thereof 116 2004
 
WILLIAM A. COOK AUSTRALIA PTY. LTD. (2)
2004/0073,289 Asymmetric stent graft attachment 51 2003
2004/0193,244 Device and method for treating thoracic aorta 26 2003
 
ABPS VENTURE ONE, LTD. (1)
2006/0167,543 Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof 128 2006
 
ADMEDUS REGEN PTY LTD (1)
2006/0193,885 Implantable biomaterial and a method of producing same 37 2005
 
AORTECH INTERNATIONAL PLC (1)
2006/0290,027 Heart valve prosthesis and method of manufacture 24 2006
 
BIOGENTIS INC. (1)
2003/0027,332 Tissue engineered heart valve 62 2002
 
Biomedical Design, Inc. (1)
6,521,179 Sterilization 28 2000
 
CELONOVA BIOSCIENCES, INC. (1)
2008/0086,205 Bioprosthetic Heart Valve With Polyphosphazene 25 2007
 
COLIBRI HEART VALVE LLC (1)
2005/0113,910 Percutaneously implantable replacement heart valve device and method of making same 173 2004
 
Dereume, Jean-Pierre G. E. (1)
6,241,738 Retrieval device for insertion into a body lumen 116 1998
 
ETHICON, INC. (1)
2003/0065,386 Radially expandable endoprosthesis device with two-stage deployment 93 2001
 
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (1)
2003/0149,476 Anchoring system for implantable heart valve prostheses 130 2002
 
GABBAY, SHLOMO (1)
5,935,163 Natural tissue heart valve prosthesis 91 1998
 
GI Dynamics, Inc. (1)
2005/0125,075 Intestinal sleeve 67 2004
 
GOLF TECH, LLC (1)
6,821,211 Sport swing analysis system 48 2001
 
JEN. CARIOTEC GMBH (1)
2007/0100,440 Device for the implantation and fixation of prosthetic valves 120 2006
 
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (1)
5,697,972 Bioprosthetic heart valves having high calcification resistance 47 1995
 
LEMAITRE ACQUISITION LLC (1)
6,183,481 Delivery system for self-expanding stents and grafts 93 1999
 
LIFESHIELD SCIENCES LLC (1)
2005/0143,804 Method and system for fixation of endoluminal devices 25 2005
 
Litana Ltd. (1)
5,876,434 Implantable medical devices of shape memory alloy 127 1997
 
LUCENT TECHNOLOGIES INC. (1)
5,841,382 Fast testing of D/A converters 39 1997
 
MEDTRONIC VASCULAR GALWAY LIMITED (1)
2003/0036,791 Implant implantation unit and procedure for implanting the unit 158 2002
 
MURES CARDIOVASCULAR RESEARCH, INC. (1)
6,214,055 Method and kit for rapid preparation of autologous tissue medical devices 55 1998
 
PERCUTANEOUS VALVE TECHNOLOGIES (1)
2008/0077,236 VALVE PROSTHESIS FOR IMPLANTATION IN BODY CHANNELS 24 2007
 
PFM MEDICAL AG (1)
2006/0224,183 Implantable device 24 2004
 
ROSS, DONALD D. (1)
5,352,240 Human heart valve replacement with porcine pulmonary valve 93 1989
 
Sadra Medical (1)
2005/0137,687 Heart valve anchor and method 144 2003
 
Sadra Medical, a Delaware Corporation (1)
2005/0137,688 Repositionable heart valve and method 244 2003
 
SORIN GROUP ITALIA S.R.L. (1)
2005/0197,695 Minimally-invasive cardiac-valve prosthesis 172 2005
 
SORIN GROUP USA, INC. (1)
6,613,086 Altering heart valve leaflet attachment geometry to influence the location and magnitude of maximum loaded stress on the leaflet 37 2000
 
SYMETIS SA (1)
2007/0213,813 Stent-valves for valve replacement and associated methods and systems for surgery 103 2006
 
TDK CORPORATION (1)
7,050,276 GMR magnetic sensing element having an antiferromagnetic layer extending beyond the track width and method for making the same 32 2003
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (1)
2002/0143,387 Stent repositioning and removal 72 2001
 
THE CLEVELAND CLINIC FOUNDATION (1)
2005/0119,728 Method for fixing tissue 24 2005
 
THE GENERAL HOSPITAL CORPORATION (1)
5,824,080 Photochemistry for the preparation of biologic grafts--allografts and xenografts 40 1996
 
UNIVERSITAT ZURICH (1)
2006/0246,584 In-vitro method for the production of a homologous stented tissue-engineered heart valve 29 2002
 
Wachauf, Gerhard (1)
7,014,655 Method for conserving biological prostheses, conserved biological prostheses and conserving solutions 25 2001
 
Other [Check patent profile for assignment information] (12)
5,332,402 Percutaneously-inserted cardiac valve 399 1992
6,120,534 Endoluminal prosthesis having adjustable constriction 122 1997
6,540,782 Artificial heart valve 54 2001
2002/0123,790 Enhanced engagement member for anchoring prosthetic devices in body lumen 78 2001
2002/0032,481 Heart valve prosthesis and sutureless implantation of a heart valve prosthesis 268 2001
6,821,297 Artificial heart valve, implantation instrument and method therefor 224 2002
2003/0040,792 Heart valve prosthesis and sutureless implantation of a heart valve prosthesis 170 2002
2004/0049,262 Stent valves and uses of same 175 2003
2005/0009,000 Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering 28 2004
2006/0064,151 Cranial aneurysm treatment arrangement 9 2005
2007/0020,248 Process for biological tissue 24 2006
2007/0123,700 Processes for removing cells and cell debris from tissue and tissue constructs used in transplantation and tissue reconstruction 24 2007

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
MIDDLE PEAK MEDICAL, INC. (1)
8,845,717 Coaptation enhancement implant, system, and method 0 2011
 
MITRALTECH LTD. (1)
8,852,272 Techniques for percutaneous mitral valve replacement and sealing 0 2012
 
Other [Check patent profile for assignment information] (1)
8,870,950 Rotation-based anchoring of an implant 0 2010

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