-glycans in lower eukaryotes
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United States of America Patent
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Nov 29, 2011
Grant Date -
Jun 18, 2009
app pub date -
Nov 7, 2008
filing date -
Jun 28, 2000
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Abstract
core structure which may then be modified further by heterologous expression of one or more enzymes, e.g., glycosyltransferases, sugar transporters and mannosidases, to yield human-like glycoproteins. For the production of therapeutic proteins, this method may be adapted to engineer cell lines in which any desired glycosylation structure may be obtained.
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