End-modified poly(beta-amino esters) and uses thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8071082
APP PUB NO 20080242626A1
SERIAL NO

11780754

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Poly(beta-amino esters) are end-modified to form materials useful in the medical as well as non-medical field. An amine-terminated poly(beta-amino ester) is reacted with an electrophile, or an acrylate-terminated poly(beta-amino ester) is reacted with a nucleophile. The inventive end-modified polymers may be used in any field where polymers have been found useful including the drug delivery arts. The end-modified polymers are particularly useful in delivery nucleic acids such as DNA or RNA. The invention also provides compositions including the inventive end-modified polymers, methods of preparing the inventive polymers, and method of using the inventive polymers.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Anderson, Daniel G Sudbury, US 93 2387
Langer, Robert S Newton, US 635 37250
Zugates, Gregory T Cambridge, US 43 492
Zumbuehl, Andreas Bern, CH 14 804

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation