Targeting PAX2 for the treatment of breast cancer
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United States of America Patent
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Dec 20, 2011
Grant Date -
Aug 19, 2010
app pub date -
Feb 18, 2010
filing date -
Oct 14, 2005
priority date (Note) -
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Abstract
The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the certain embodiments, the method of inhibiting expression of PAX2 is to administrate the subject a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 or by increasing expression of DEFB1 is also provided.
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