Derivatives of 8-epiblechnic acid and their effects on down-regulation of endothelin (ETA) receptor mRNA
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United States of America Patent
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Dec 20, 2011
Grant Date -
Feb 25, 2010
app pub date -
Aug 18, 2009
filing date -
Aug 19, 2008
priority date (Note) -
Expired
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Abstract
The present application discloses derivatives of 8-epiblechnic acid and use thereof in treating a disease related to endothelin receptor A or endothelin-1 (ET-1) over-expression, such as hypertension, cancer, atherosclerosis, and myocardial infarction.
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