Computer-aided discovery of biomarker profiles in complex biological systems
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United States of America Patent
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Dec 20, 2011
Grant Date -
Apr 9, 2009
app pub date -
Aug 28, 2008
filing date -
Aug 29, 2007
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Abstract
The invention relates to computational methods, systems and apparatus useful in the analysis of sets of biomolecules in an accessible body fluid or tissue sample from a patient, which biomolecules collectively or individually are candidates to serve as biomarkers, i.e., biomolecules which together or individually upon detection or change are indicative that the patient is in some biological state, such as a diseased state. The methods permit one to examine such potential biological markers to determine whether each one is indeed present as a consequence of the biological state, or as an artifact of the biomarker search protocol.
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