Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
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United States of America Patent
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Dec 27, 2011
Grant Date -
Nov 10, 2005
app pub date -
Mar 30, 2005
filing date -
Sep 20, 2002
priority date (Note) -
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Abstract
A pharmaceutical dosage form comprising a controlled release component comprising an antihyperglycemic drug in combination with a second component comprising a thiazolidinedione derivative and a disintegrating agent is herein disclosed and described. The dosage formulation exhibits a significant increase in bioavailability of the thiazolidinedione derivative component compared to conventional immediate release dosage forms containing only a thiazolidinedione derivative.
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