Unified probabilistic framework for predicting and detecting seizure onsets in the brain and multitherapeutic device

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United States of America Patent

PATENT NO 8086294
SERIAL NO

11837814

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Abstract

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A method and system for assessing a quality of life index to adjust an implanted device to optimize patient-specific feature signals and treatment therapies. Accumulated energy of intracranial electroencephalogram (IEEG) signals is calculated over multiple data channels during seizures over a fixed time period. Accumulated energy of a treatment control is calculated over the multiple data channels over all times of activation of the implanted device over the fixed time period. The accumulated energy of both the IEEG signals and treatment control are weighted by seizure and treatment factors to determine a quality value for the fixed time period. A quality of life index is determined as a weighted average of current and previous quality values for a plurality of fixed time periods.

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Patent Owner(s)

Patent OwnerAddress
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA3600 CIVIC CENTER BOULEVARD 9TH FLOOR PHILADELPHIA PA 19104

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Echauz, Javier Ramón Atlanta, US 4 81
Esteller, Rosana Marietta, US 118 2197
Litt, Brian Merion Station, US 26 2501
Vachtsevanos, George John Marietta, US 7 956

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