US Patent No: 8,088,060

Number of patents in Portfolio can not be more than 2000

Progenitor endothelial cell capturing with a drug eluting implantable medical device

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ALSO PUBLISHED AS: 20070123977
ATTORNEY / AGENT: (SPONSORED)
 

Importance

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Abstract

A medical device for implantation into vessels or luminal structures within the body is provided, which stimulates positive blood vessel remodeling. The medical device, such as a stent and a synthetic graft, is provided with a coating with a pharmaceutical composition containing a controlled-release matrix and one or more pharmaceutical substances for direct delivery of drugs to surrounding tissues. The coating on the medical device further comprises one or more barrier layers, and a ligand such as a peptide, an antibody or a small molecule for capturing progenitor endothelial cells in the blood contacting surface of the device for restoring an endothelium at the site of injury. In particular, the drug-coated stents are for use, for example, in balloon angioplasty procedures for preventing or inhibiting restenosis.

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First Claim

Related Publications

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ORBUSNEICH MEDICAL, INC.FORT LAUDERDALE, FL25

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cottone,, Jr Robert John - 8 21
Parker, Sherry Sunrise, FL 5 51
Yoklavich, Margaret San Jose, CA 5 64

Cited Art

Patent Info (Count) # Cites Year
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (144)
5,441,515 Ratcheting stent 446 1993
5,423,885 Stent capable of attachment within a body lumen 386 1993
5,443,458 Multilayered biodegradable stent and method of manufacture 301 1993
5,629,077 Biodegradable mesh and film stent 208 1994
5,649,977 Metal reinforced polymer stent 400 1994
5,707,385 Drug loaded elastic membrane and method for delivery 233 1994
5,637,113 Polymer film for wrapping a stent structure 361 1994
5,605,696 Drug loaded polymeric material and method of manufacture 523 1995
5,569,295 Expandable stents and method for making same 328 1995
5,632,840 Method of making metal reinforced polymer stent 190 1995
5,593,434 Stent capable of attachment within a body lumen 234 1995
5,618,299 Ratcheting stent 236 1995
5,766,710 Biodegradable mesh and film stent 223 1996
5,649,952 Expandable stents and method for making same 185 1996
5,700,286 Polymer film for wrapping a stent structure 521 1996
5,733,330 Balloon-expandable, crush-resistant locking stent 128 1997
5,843,172 Porous medicated stent 333 1997
6,240,616 Method of manufacturing a medicated porous metal prosthesis 368 1997
5,916,234 Expandable stents and method for making same 68 1997
5,897,911 Polymer-coated stent structure 164 1997
5,766,239 Balloon-expandable, crush resistant locking stent and method of loading the same 117 1997
6,179,867 Flexible stent and method of use 101 1998
5,976,182 Balloon-expandable, crush-resistant locking stent and method of loading the same 122 1998
6,273,910 Stent with varying strut geometry 123 1999
6,273,911 Variable strength stent 114 1999
6,312,459 Stent design for use in small vessels 140 1999
6,540,774 Stent design with end rings having enhanced strength and radiopacity 45 1999
6,287,628 Porous prosthesis and a method of depositing substances into the pores 287 1999
6,379,381 Porous prosthesis and a method of depositing substances into the pores 322 1999
6,203,551 Chamber for applying therapeutic substances to an implant device 227 1999
6,713,119 Biocompatible coating for a prosthesis and a method of forming the same 155 1999
6,527,801 Biodegradable drug delivery material for stent 243 2000
6,616,689 Intravascular stent 45 2000
6,395,326 Apparatus and method for depositing a coating onto a surface of a prosthesis 387 2000
6,800,089 Mechanical attachment method of cover materials on stents 17 2000
6,585,765 Implantable device having substances impregnated therein and a method of impregnating the same 215 2000
6,503,954 Biocompatible carrier containing actinomycin D and a method of forming the same 189 2000
6,555,157 Method for coating an implantable device and system for performing the method 210 2000
6,574,851 Stent made by rotational molding or centrifugal casting and method for making the same 76 2000
6,451,373 Method of forming a therapeutic coating onto a surface of an implantable prosthesis 216 2000
6,254,632 Implantable medical device having protruding surface structures for drug delivery and cover attachment 391 2000
6,805,898 Surface features of an implantable medical device 136 2000
6,506,437 Methods of coating an implantable device having depots formed in a surface thereof 289 2000
6,979,347 Implantable drug delivery prosthesis 24 2000
6,783,793 Selective coating of medical devices 64 2000
6,913,617 Method for creating a textured surface on an implantable medical device 51 2000
6,503,556 Methods of forming a coating for a prosthesis 195 2000
6,540,776 Sheath for a prosthesis and methods of forming the same 191 2000
6,565,599 Hybrid stent 94 2000
6,663,662 Diffusion barrier layer for implantable devices 210 2000
6,759,054 Ethylene vinyl alcohol composition and coating 113 2000
6,790,228 Coating for implantable devices and a method of forming the same 165 2000
6,346,110 Chamber for applying therapeutic substances to an implantable device 159 2001
6,544,582 Method and apparatus for coating an implantable device 205 2001
6,596,022 Expandable stents and method for making same 36 2001
7,008,642 Compositions for achieving a therapeutic effect in an anatomical structure and methods of using the same 4 2001
6,541,116 Superoxide dismutase or superoxide dismutase mimic coating for an intracorporeal medical device 32 2001
6,712,845 Coating for a stent and a method of forming the same 208 2001
6,818,247 Ethylene vinyl alcohol-dimethyl acetamide composition and a method of coating a stent 25 2001
6,660,034 Stent for increasing blood flow to ischemic tissues and a method of using the same 198 2001
6,773,455 Stent with reinforced struts and bimodal deployment 15 2001
6,743,462 Apparatus and method for coating implantable devices 141 2001
6,468,302 Variable strength stent 42 2001
6,673,385 Methods for polymeric coatings stents 157 2001
6,585,755 Polymeric stent suitable for imaging by MRI and fluoroscopy 206 2001
6,605,110 Stent with enhanced bendability and flexibility 32 2001
6,607,554 Universal stent link design 31 2001
6,629,992 Sheath for self-expanding stent 53 2001
6,860,898 Self-expanding stent with enhanced delivery precision and stent delivery system 38 2001
6,753,071 Rate-reducing membrane for release of an agent 203 2001
7,150,853 Method of sterilizing a medical device 3 2001
6,663,880 Permeabilizing reagents to increase drug delivery and a method of local delivery 125 2001
7,175,874 Apparatus and method for coating implantable devices 11 2001
6,866,805 Hybrid intravascular stent 65 2001
6,709,514 Rotary coating apparatus for coating implantable medical devices 122 2001
6,616,765 Apparatus and method for depositing a coating onto a surface of a prosthesis 180 2002
6,602,284 Variable strength stent 27 2002
6,511,505 Variable strength stent 72 2002
7,022,334 Therapeutic composition and a method of coating implantable medical devices 21 2002
6,994,867 Biocompatible carrier containing L-arginine 34 2002
7,005,137 Coating for implantable medical devices 25 2002
7,011,842 Polycationic peptide coatings and methods of making the same 7 2002
7,033,602 Polycationic peptide coatings and methods of coating implantable medical devices 10 2002
7,056,523 Implantable medical devices incorporating chemically conjugated polymers and oligomers of L-arginine 6 2002
7,070,798 Coatings for implantable medical devices incorporating chemically-bound polymers and oligomers of L-arginine 14 2002
7,217,426 Coatings containing polycationic peptides for cardiovascular therapy 18 2002
7,247,313 Polyacrylates coatings for implantable medical devices 32 2002
6,733,768 Composition for coating an implantable prosthesis 109 2002
7,175,873 Rate limiting barriers for implantable devices and methods for fabrication thereof 18 2002
7,294,329 Poly(vinyl acetal) coatings for implantable medical devices 16 2002
6,723,120 Medicated porous metal prosthesis 170 2002
6,852,124 Variable strength stent 47 2002
7,232,573 Stent coatings containing self-assembled monolayers 19 2002
7,135,038 Drug eluting stent 23 2002
7,087,263 Rare limiting barriers for implantable medical devices 11 2002
6,896,965 Rate limiting barriers for implantable devices 19 2002
7,022,372 Compositions for coating implantable medical devices 2 2002
7,144,422 Drug-eluting stent and methods of making the same 15 2002
6,908,624 Coating for implantable devices and a method of forming the same 84 2002
7,094,256 Coatings for implantable medical device containing polycationic peptides 22 2002
6,899,729 Stent for treating vulnerable plaque 37 2002
6,896,697 Intravascular stent 56 2002
7,316,710 Flexible stent 9 2002
6,991,681 Method and apparatus for coating an implantable device 7 2003
6,926,919 Method for fabricating a coating for a medical device 31 2003
7,255,891 Method for coating implantable medical devices 5 2003
7,288,609 Coatings for drug delivery devices based on poly (orthoesters) 7 2003
6,860,946 System for the process of coating implantable medical devices 48 2003
7,258,891 Stent mounting assembly and a method of using the same to coat a stent 13 2003
7,279,174 Stent coatings comprising hydrophilic additives 45 2003
6,846,323 Intravascular stent 133 2003
7,186,789 Bioabsorbable, biobeneficial polyester polymers for use in drug eluting stent coatings 7 2003
6,893,458 Self-expanding stent with enhanced delivery precision and stent delivery system 5 2003
7,273,492 Stent for treating vulnerable plaque 5 2003
7,323,210 Method for depositing a coating onto a surface of a prosthesis 12 2003
7,285,304 Fluid treatment of a polymeric coating on an implantable medical device 17 2003
7,056,591 Hydrophobic biologically absorbable coatings for drug delivery devices and methods for fabricating the same 45 2003
7,169,404 Biologically absorbable coatings for implantable devices and methods for fabricating the same 6 2003
6,986,899 Composition for coating an implantable prosthesis 24 2003
7,169,173 Composite stent with regioselective material and a method of forming the same 19 2003
7,198,675 Stent mandrel fixture and method for selectively coating surfaces of a stent 46 2003
7,014,861 Permeabilizing reagents to increase drug delivery and a method of local delivery 11 2003
7,329,413 Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof 8 2003
7,261,946 Block copolymers of acrylates and methacrylates with fluoroalkenes 7 2003
7,335,391 Method for coating implantable devices 8 2003
7,220,816 Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same 32 2003
7,014,913 Rate-reducing membrane for release of an agent 7 2004
7,115,300 Method of coating implantable medical devices 5 2004
7,329,366 Method of polishing implantable medical devices to lower thrombogenecity and increase mechanical stability 5 2004
7,077,860 Method of reducing or eliminating thrombus formation 13 2004
7,297,159 Selective coating of medical devices 3 2004
7,311,980 Polyactive/polylactic acid coatings for an implantable device 8 2004
7,335,314 Method of making an implantable medical device 9 2004
7,244,443 Polymers of fluorinated monomers and hydrophilic monomers 6 2004
7,229,471 Compositions containing fast-leaching plasticizers for improved performance of medical devices 55 2004
7,166,680 Blends of poly(ester amide) polymers 14 2004
7,214,759 Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same 8 2004
7,202,325 Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles 16 2005
7,063,884 Stent coating 16 2005
7,247,364 Coating for implantable medical devices 7 2005
7,291,166 Polymeric stent patterns 10 2005
7,297,758 Method for extending shelf-life of constructs of semi-crystallizable polymers 1 2005
7,301,001 Bioabsorbable, biobeneficial polyester polymers for stent coatings 1 2006
7,312,299 Bioabsorbabl, biobeneficial polyester polymers for stent coatings 1 2006
 
BOSTON SCIENTIFIC SCIMED, INC. (116)
5,304,121 Drug delivery system making use of a hydrogel polymer coating 421 1991
5,366,504 Tubular medical prosthesis 387 1992
5,674,192 Drug delivery 174 1993
5,449,382 Minimally invasive bioactivated endoprosthesis for vessel repair 325 1994
5,588,962 Drug treatment of diseased sites deep within the body 59 1994
5,439,446 Stent and therapeutic delivery system 234 1994
5,634,936 Device for closing a septal defect 335 1995
6,515,009 Therapeutic inhibitor of vascular smooth muscle cells 55 1995
5,811,447 Therapeutic inhibitor of vascular smooth muscle cells 170 1995
6,171,609 Therapeutic inhibitor of vascular smooth muscle cells 154 1995
5,718,159 Process for manufacturing three-dimensional braided covered stent 99 1996
5,758,562 Process for manufacturing braided composite prosthesis 91 1996
5,733,925 Therapeutic inhibitor of vascular smooth muscle cells 328 1996
5,871,437 Radioactive stent for treating blood vessels to prevent restenosis 107 1996
5,788,979 Biodegradable coating with inhibitory properties for application to biocompatible materials 300 1997
6,270,515 Device for closing a septal defect 129 1997
6,035,856 Percutaneous bypass with branching vessel 101 1997
5,981,568 Therapeutic inhibitor of vascular smooth muscle cells 223 1997
6,306,421 Therapeutic inhibitor of vascular smooth muscle cells 73 1997
5,879,697 Drug-releasing coatings for medical devices 174 1997
5,857,998 Stent and therapeutic delivery system 131 1997
5,980,564 Bioabsorbable implantable endoprosthesis with reservoir 159 1997
6,174,330 Bioabsorbable marker having radiopaque constituents 193 1997
6,245,103 Bioabsorbable self-expanding stent 163 1997
6,340,367 Radiopaque markers and methods of using the same 63 1997
6,019,786 Braided composite prosthesis 66 1997
5,980,972 Method of applying drug-release coatings 405 1997
5,957,974 Stent graft with braided polymeric sleeve 108 1997
6,391,052 Stent with collagen 126 1997
6,626,939 Stent-graft with bioabsorbable structural support 142 1997
6,099,562 Drug coating with topcoat 450 1997
5,980,566 Vascular and endoluminal stents with iridium oxide coating 102 1998
6,217,609 Implantable endoprosthesis with patterned terminated ends and methods for making same 33 1998
6,348,065 Longitudinally flexible expandable stent 161 1998
6,364,893 Stent lining 43 1998
6,156,064 Stent-graft-membrane and method of making the same 99 1998
6,099,561 Vascular and endoluminal stents with improved coatings 251 1998
6,159,142 Stent with radioactive coating for treating blood vessels to prevent restenosis 75 1998
6,342,068 Three-dimensional braided stent 31 1998
6,350,277 Stents with temporary retaining bands 124 1999
6,419,692 Surface protection method for stents and balloon catheters for drug delivery 281 1999
6,312,457 Intraluminal lining 65 1999
6,231,600 Stents with hybrid coating for medical devices 305 1999
6,500,203 Process for making stent graft with braided polymeric sleeve 33 1999
6,149,680 Stent loading tool 24 1999
6,258,121 Stent coating 346 1999
6,358,989 Therapeutic inhibitor of vascular smooth muscle cells 45 1999
6,652,582 Bioabsorbable endoprosthesis having porosity for by-product collection 59 1999
6,440,164 Implantable prosthetic valve 211 1999
6,585,758 Multi-section filamentary endoluminal stent 73 1999
6,616,591 Radioactive compositions and methods of use thereof 8 1999
6,390,098 Percutaneous bypass with branching vessel 31 1999
6,689,162 Braided composite prosthesis 26 2000
6,488,703 Helical stent design 40 2000
6,426,145 Radiopaque compositions for visualization of medical devices 26 2000
6,284,305 Drug coating with topcoat 220 2000
6,387,121 Vascular and endoluminal stents with improved coatings 167 2000
6,736,828 Method for performing endoluminal fundoplication and apparatus for use in the method 110 2000
6,709,455 Stent-graft-membrane and method of making the same 36 2000
6,890,350 Combination self-expandable, balloon-expandable endoluminal device 10 2000
6,491,666 Microfabricated devices for the delivery of molecules into a carrier fluid 170 2000
6,545,097 Drug delivery compositions and medical devices containing block copolymer 184 2000
7,153,322 Tubular stent with oval struts 9 2000
7,208,002 Expansion-assisting delivery system for self-expanding stent 3 2001
6,592,617 Three-dimensional braided covered stent 81 2001
6,752,829 Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same 75 2001
6,613,077 Stent with controlled expansion 52 2001
6,602,283 Stent design 7 2001
6,719,934 Process for making bioabsorbable self-expanding stent 87 2001
6,620,122 Gastric pseudocyst drainage and stent delivery system for use therein 5 2001
7,004,962 Neuroaneurysm occlusion and delivery device and method of using same 1 2001
6,685,745 Delivering an agent to a patient's body 15 2001
6,491,938 Therapeutic inhibitor of vascular smooth muscle cells 69 2001
6,599,928 Therapeutic inhibitor of vascular smooth muscle cells 44 2001
6,921,390 Long-term indwelling medical devices containing slow-releasing antimicrobial agents and having a surfactant surface 36 2001
6,926,733 Method for enhancing sheet or tubing metal stent radiopacity 9 2001
6,620,194 Drug coating with topcoat 51 2001
6,896,696 Flexible and expandable stent 29 2001
6,827,737 EPTFE covering for endovascular prostheses and method of manufacture 50 2001
6,893,431 Medical device for delivering patches 53 2001
6,719,784 Counter rotational layering of ePTFE to improve mechanical properties of a prosthesis 36 2001
6,569,441 Therapeutic inhibitor of vascular smooth muscle cells 54 2001
6,589,546 Polymeric coatings for controlled delivery of active agents 27 2001
6,663,881 Therapeutic inhibitor of vascular smooth muscle cells 49 2001
7,160,317 Multiple-wing balloon catheter to reduce damage to coated expandable medical implants 17 2002
6,755,869 Intragastric prosthesis for the treatment of morbid obesity 137 2002
7,022,132 Stents with temporary retaining bands 21 2002
2002/0095,208 Stent 51 2002
7,094,369 Processes for manufacturing polymeric microspheres 14 2002
7,105,021 Implantable textile prostheses having PTFE cold drawn yarns 4 2002
6,830,575 Method and device for providing full protection to a stent 53 2002
6,656,156 Dual surface protection coating for drug delivery balloon catheters and stents 19 2002
7,044,962 Implantable prosthesis with displaceable skirt 6 2002
6,685,739 Implantable prosthetic valve 130 2002
6,537,256 Microfabricated devices for the delivery of molecules into a carrier fluid 96 2002
6,918,869 System for administering a combination of therapies to a body lumen 46 2002
6,656,162 Implantable drug delivery stents 164 2002
6,720,350 Therapeutic inhibitor of vascular smooth muscle cells 37 2002
7,261,915 Electrohydrodynamic coating fluid delivery apparatus and method 1 2003
7,052,513 Three-dimensional braided covered stent 9 2003
7,326,571 Decellularized bone marrow extracellular matrix 4 2003
6,989,071 Stent with channel(s) for containing and delivering biologically active material and method for manufacturing the same 23 2003
7,052,488 Implantable drug delivery device 58 2003
7,060,319 method for using an ultrasonic nozzle to coat a medical appliance 8 2003
7,118,593 Extendible stent apparatus 14 2003
6,840,957 Implantable prosthetic valve 55 2003
6,997,989 Medical implant processing chamber 1 2003
7,041,130 Stent for controlled release of drug 59 2004
7,241,344 Apparatus and method for electrostatic spray coating of medical devices 4 2004
7,090,699 Intragastric prosthesis for the treatment of morbid obesity 27 2004
6,997,948 Bioabsorbable self-expanding stent 14 2004
7,335,264 Differentially coated medical devices, system for differentially coating medical devices, and coating method 2 2004
7,060,056 Biocompatible pharmaceutical articles 4 2004
7,267,686 Implantable prosthetic valve 31 2004
2006/0224,231 Endoprostheses 6 2005
7,279,005 Bioabsorbable self-expanding stent 15 2006
 
MEDTRONIC, INC. (56)
4,515,160 Cardiac pacemaker synchronized programming 5 1982
4,886,062 Intravascular radially expandable stent and method of implant 1153 1987
6,113,621 Intravascular stent 12 1992
5,324,261 Drug delivery balloon catheter with line of weakness 70 1992
5,957,971 Intraluminal stent 56 1993
5,443,496 Intravascular radially expandable stent 363 1993
5,370,614 Method for making a drug delivery balloon catheter 66 1993
5,545,208 Intralumenal drug eluting prosthesis 260 1993
5,510,077 Method of making an intraluminal stent 90 1994
5,571,166 Method of making an intraluminal stent 161 1994
5,591,224 Bioelastomeric stent 227 1994
5,599,352 Method of making a drug eluting stent 157 1994
5,782,903 Intravascular stent and method 22 1994
5,613,981 Bidirectional dual sinusoidal helix stent 98 1995
5,554,182 Method for preventing restenosis 148 1995
5,591,227 Drug eluting stent 215 1995
5,628,785 Bioelastomeric stent 103 1995
5,697,967 Drug eluting stent 240 1995
5,725,567 Method of making a intralumenal drug eluting prosthesis 90 1995
5,800,507 Intraluminal stent 102 1995
5,837,008 Intravascular stent and method 301 1995
5,849,034 Intraluminal stent 60 1995
5,851,217 Intralumenal drug eluting prosthesis 77 1995
5,871,535 Intralumenal drug eluting prosthesis 52 1995
6,004,346 Intralumenal drug eluting prosthesis 46 1995
5,624,411 Intravascular stent and method 457 1995
5,679,400 Intravascular stent and method 392 1995
5,820,917 Blood-contacting medical device and method 216 1995
5,893,840 Releasable microcapsules on balloon catheters 112 1996
5,776,184 Intravasoular stent and method 322 1996
5,824,048 Method for delivering a therapeutic substance to a body lumen 363 1996
5,833,651 Therapeutic intraluminal stents 174 1996
5,851,231 Intralumenal drug eluting prosthesis 71 1996
5,843,168 Double wave stent with strut 52 1997
5,951,586 Intraluminal stent 60 1997
6,106,454 Medical device for delivering localized radiation 76 1997
6,203,536 Medical device for delivering a therapeutic substance and method therefor 57 1997
5,997,468 Intraluminal drug eluting prosthesis method 152 1997
5,865,814 Blood contacting medical device and method 359 1997
5,994,444 Polymeric material that releases nitric oxide 60 1997
6,013,099 Medical device for delivering a water-insoluble therapeutic salt or substance 93 1998
6,080,190 Intraluminal stent 106 1998
6,206,914 Implantable system with drug-eluting cells for on-demand local drug delivery 165 1998
5,997,563 Implantable stent having variable diameter 43 1998
6,228,845 Therapeutic intraluminal stents 92 1998
6,613,079 Radially-expandable stent with controllable force profile 28 1999
6,287,336 Variable flexibility stent 67 1999
6,187,370 Medical device for delivering a therapeutic substance and method therefor 38 1999
6,331,189 Flexible medical stent 78 1999
6,812,217 Medical device and methods of use 2 2000
6,824,561 Implantable system with drug-eluting cells for on-demand local drug delivery 63 2000
6,730,120 Medical device for delivering a therapeutic substance and method therefor 49 2001
6,399,144 Medical device for delivering a therapeutic substance and method therefor 40 2001
6,447,443 Method for organ positioning and stabilization 76 2001
6,997,949 Medical device for delivering a therapeutic agent and method of preparation 17 2002
7,031,775 Method and system for myocardial infarction repair 9 2003
 
ORBUSNEICH MEDICAL, INC. (20)
6,117,165 Expandable intraluminal endoprosthesis 116 1998
7,108,714 Expandable intraluminal endoprosthesis 19 2000
7,037,332 Medical device with coating that promotes endothelial cell adherence 14 2001
7,329,277 Stent having helical elements 37 2001
2003/0229,393 Medical device with coating that promotes cell adherence and differentiation 49 2003
2004/0039,441 Drug eluting implantable medical device 58 2003
2005/0043,787 Medical device with coating that promotes endothelial cell adherence 9 2004
2005/0025,752 Medical device with coating for capturing genetically-altered cells and methods for using same 11 2004
2005/0271,701 Progenitor endothelial cell capturing with a drug eluting implantable medical device 16 2005
2006/0121,012 Medical device with coating for capturing genetically-altered cells and methods of using same 4 2005
2006/0135,476 Medical device with coating that promotes endothelial cell adherence and differentiation 29 2005
2007/0042,017 Medical device with coating that promotes endothelial cell adherence and differentiation 4 2006
2007/0213,801 Medical device with coating that promotes endothelial cell adherence and differentiation 3 2006
2007/0196,422 Medical device with coating that promotes endothelial cell adherence and differentiation 3 2006
2007/0123,977 Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device 14 2006
2007/0128,723 Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device 3 2006
2007/0141,107 Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device 4 2006
2007/0129,789 Progenitor Endothelial Cell Capturing with a Drug Eluting Implantable Medical Device 34 2006
2007/0156,232 Medical Device with Coating that Promotes Endothelial Cell Adherence 2 2006
2007/0191,932 MEDICAL DEVICE WITH COATING FOR CAPTURING GENETICALLY-ALTERED CELLS AND METHODS FOR USING SAME 3 2007
 
ETHICON, INC. (19)
6,110,188 Anastomosis method 372 1998
6,126,675 Bioabsorbable device and method for sealing vascular punctures 113 1999
6,153,252 Process for coating stents 560 1999
6,338,739 Biodegradable stent 76 1999
6,494,908 Removable stent for body lumens 91 1999
6,224,894 Copolymers of absorbable polyoxaesters 56 2000
7,030,127 Composition and medical devices utilizing bioabsorbable polymeric waxes 4 2001
6,423,092 Biodegradable stent 130 2001
6,537,312 Biodegradable stent 30 2001
6,629,988 Composite staple for completing an anastomosis 140 2001
7,163,562 Biodegradable stent 4 2002
6,989,034 Attachment of absorbable tissue scaffolds to fixation devices 59 2002
7,026,374 Injectable microdispersions for medical applications 7 2002
7,166,134 Biodegradable stent 7 2002
7,034,037 Compositions and medical devices utilizing bioabsorbable polymeric waxes and rapamycin 6 2002
7,012,106 Reinforced implantable medical devices 13 2003
7,220,272 Composite staple and method for using same 80 2003
7,169,187 Biodegradable stent 11 2003
6,981,944 Implantable surgical mesh having a lubricious coating 10 2004
 
ABBOTT LABORATORIES (17)
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5,527,322 Device and method for suturing of internal puncture sites 312 1993
5,779,719 Device and method for the percutaneous suturing of a vascular puncture site 155 1994
5,902,311 Low profile intraluminal suturing device and method 92 1995
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5,860,991 Method for the percutaneous suturing of a vascular puncture site 226 1997
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6,117,145 Method and device for providing hemostasis at vascular penetration sites 51 1997
6,206,893 Device and method for suturing of internal puncture sites 214 1998
6,136,010 Articulating suturing device and method 133 1999
7,001,400 Articulating suturing device and method 81 2000
6,517,553 Device and method for suturing of internal puncture sites 62 2001
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7,029,480 Device and method for suturing of internal puncture sites 28 2002
7,128,756 Endoprosthesis having foot extensions 48 2003
7,208,190 Method of loading beneficial agent to a prosthesis by fluid-jet application 31 2003
 
BOSTON SCIENTIFIC CORPORATION (16)
5,674,276 Tubular medical prosthesis 117 1994
5,954,706 Drug delivery 109 1995
5,685,847 Stent and therapeutic delivery system 68 1995
5,843,089 Stent lining 112 1996
5,868,719 Drug delivery balloon catheter device 41 1997
6,494,861 Drug delivery system 9 1997
6,221,099 Tubular medical prosthesis 64 1997
5,968,092 Method for making a biodegradable stent 129 1998
5,954,693 Replenishable stent and delivery system 69 1998
6,344,028 Replenishable stent and delivery system 14 1999
6,514,283 Intraluminal lining 97 2001
7,090,655 Replenishable stent and delivery system 6 2001
6,740,121 Intragastric stent for duodenum bypass 131 2002
7,060,087 Intraluminal lining 3 2003
6,946,002 Intragastric stent for duodenum bypass 21 2004
7,175,669 Intragastric stent for duodenum bypass 23 2005
 
UNITED STATES SURGICAL CORPORATION (15)
4,920,203 Medical devices fabricated from homopolymers and copolymers having recurring carbonate units 82 1988
5,145,945 Homopolymers and copolymers having recurring carbonate units 36 1990
5,152,781 Medical devices fabricated from homopolymers and copolymers having recurring carbonate units 60 1992
5,358,677 Methods of forming bioabsorbable objects from polyvinyl alcohol 3 1992
5,256,764 Medical devices fabricated from homopolymers and copolymers having recurring carbonate units 25 1992
5,274,074 Medical devices fabricated from homopolymers and copolymers having recurring carbonate units 36 1992
5,626,611 Composite bioabsorbable materials and surgical articles made therefrom 63 1994
5,412,068 Medical devices fabricated from homopolymers and copolymers having recurring carbonate units 42 1994
5,486,593 Medical devices fabricated from copolymers having recurring carbonate units 22 1994
5,578,046 Composite bioabsorbable materials and surgical articles made thereform 90 1995
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6,093,200 Composite bioabsorbable materials and surgical articles made therefrom 24 1997
6,315,788 Composite materials and surgical articles made therefrom 46 1998
6,526,320 Apparatus for thermal treatment of tissue 81 2001
7,097,907 Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom 3 2003
 
DR. REDDY'S LABORATORIES LIMITED (13)
7,173,032 Methods and compositions of novel triazine compounds 5 2003
7,112,587 Methods and compositions of novel triazine compounds 14 2003
7,132,423 Methods and compositions of novel triazine compounds 3 2003
7,163,943 Methods and compositions of novel triazine compounds 5 2003
7,169,785 Methods and compositions of novel triazine compounds 3 2003
7,335,770 Triazine compounds and their analogs, compositions, and methods 1 2004
7,169,784 Medical devices employing triazine compounds and compositions thereof 2 2004
7,238,692 Medical devices employing triazine compounds and compositions thereof 1 2004
7,268,134 Medical devices employing triazine compounds and compositions thereof 1 2004
7,265,114 Methods and compositions of novel triazine compounds 1 2005
7,332,490 Methods and compositions of novel triazine compounds 1 2006
7,332,488 Methods and compositions of novel triazine compounds 1 2006
7,335,656 Medical devices employing triazine compounds and compositions thereof 1 2006
 
GENZYME CORPORATION (13)
5,213,580 Biodegradable polymeric endoluminal sealing process 259 1992
5,674,287 Biodegradable polymeric endoluminal sealing process, apparatus and polymeric product for use therein 57 1994
5,634,946 Polymeric endoluminal paving process 43 1995
5,662,712 Apparatus for intraluminal photothermoforming 84 1995
5,741,323 Polymeric article for intraluminal photothermoforming 49 1995
5,749,915 Polymeric endoluminal paving process 61 1995
5,749,922 Biodegradable polymeric endoluminal sealing process, apparatus and polymeric products for use therein 46 1995
5,800,538 Biodegradable polymeric endoluminal sealing process 25 1995
5,947,977 Apparatus and polymeric endoluminal sealing 72 1995
5,849,035 Methods for intraluminal photothermoforming 41 1995
6,176,871 Apparatus and methods for intraluminal photothermoforming 33 1998
6,531,147 Compliant tissue sealants 30 2001
7,022,343 Controlled release of anti-arrhythmic agents 2 2001
 
SCIMED LIFE SYSTEMS, INC. (13)
5,464,450 Biodegradable drug delivery vascular stent 245 1994
5,551,954 Biodegradable drug delivery vascular stent 253 1994
5,769,883 Biodegradable drug delivery vascular stent 265 1995
6,409,716 Drug delivery 71 1997
6,387,124 Biodegradable drug delivery vascular stent 93 1999
6,403,758 Bioresorbable compositions for implantable prostheses 27 1999
6,652,575 Stent with smooth ends 91 2001
6,890,339 Stent lining 28 2002
6,869,443 Biodegradable drug delivery vascular stent 98 2002
7,160,319 Multi-section filamentary endoluminal stent 29 2003
7,074,229 Device for performing endoluminal fundoplication 14 2004
7,056,412 Counter rotational layering of ePTFE to improve mechanical properties of a prosthesis 8 2004
6,979,473 Method for fine bore orifice spray coating of medical devices and pre-filming atomization 3 2004
 
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (10)
4,487,715 Method of conjugating oligopeptides 26 1982
5,635,482 Synthetic compounds and compositions with enhanced cell binding 27 1994
5,674,848 Bioreactor compositions with enhanced cell binding 6 1994
5,661,127 Peptide compositions with growth factor-like activity 12 1995
5,780,436 Peptide compositions with growth factor-like activity 7 1996
5,958,428 Synthetic compounds and compositions with enhanced cell binding 7 1997
5,891,192 Ion-implanted protein-coated intralumenal implants 128 1997
6,258,939 PSCA antibodies and hybridomas producing them 25 1998
6,197,586 Chondrocyte-like cells useful for tissue engineering and methods 22 1998
6,268,348 Synthetic compounds and compositions with enhanced cell binding 6 1999
 
AVENTIS PHARMACEUTICALS INC. (9)
6,180,632 Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases 152 1998
6,245,760 Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases 136 1998
6,524,347 Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases 124 2000
6,528,526 Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases 127 2000
6,482,834 Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases 140 2001
6,696,434 Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases 2 2002
6,846,815 Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases 5 2003
6,852,712 Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases 1 2003
6,821,962 Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and /or p56lck tyrosine kinases 1 2003
 
CORDIS CORPORATION (9)
5,102,417 Expandable intraluminal graft, and method and apparatus for implanting an expandable intraluminal graft 716 1988
5,968,070 Covered expanding mesh stent 84 1997
6,273,913 Modified stent useful for delivery of drugs along stent strut 484 1998
6,565,600 Articulated expandable intraluminal stent 9 2001
6,852,122 Coated endovascular AAA device 58 2003
7,270,675 Method of forming a tubular membrane on a structural frame 12 2003
7,070,616 Implantable valvular prosthesis 62 2003
7,212,100 Medical product expiration alerting 1 2005
7,230,521 Method for inventory control for medical products 3 2005
 
MICRO THERAPEUTICS, INC. (9)
6,007,573 Intracranial stent and method of use 55 1996
6,254,628 Intracranial stent 141 1996
6,432,128 Intracranial stent and method of use 16 1999
6,565,601 Methods for vascular reconstruction of diseased arteries 14 2001
6,569,190 Methods for treating aneurysms 15 2001
6,669,719 Intracranial stent and method of use 37 2001
7,323,005 Intracranial stent and method of use 5 2002
7,011,677 Methods for vascular reconstruction of diseased arteries 9 2003
7,083,643 Methods for treating aneurysms 4 2003
 
INTEGRATED VASCULAR SYSTEMS, INC. (8)
6,197,042 Vascular sheath with puncture site closure apparatus and methods of use 175 2000
6,461,364 Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use 72 2000
6,391,048 Integrated vascular device with puncture site closure component and sealant and methods of use 120 2000
6,626,918 Apparatus and methods for positioning a vascular sheath 64 2000
6,695,867 Plunger apparatus and methods for delivering a closure device 87 2002
6,749,621 Sheath apparatus and methods for delivering a closure device 97 2002
6,942,674 Apparatus and methods for delivering a closure device 108 2002
7,144,411 Apparatus and methods for positioning a vascular sheath 47 2003
 
ETHICON ENDO-SURGERY, INC. (7)
6,635,068 Occlusion, anchoring, tensioning and flow direction apparatus and methods for use 163 1999
6,450,989 Dilating and support apparatus with disease inhibitors and methods for use 121 1999
7,011,654 Dilating and support apparatus with disease inhibitors and methods for use 29 2001
7,083,629 Overtube apparatus for insertion into a body 83 2002
7,229,428 Method and device for use in endoscopic organ procedures 38 2002
7,220,237 Method and device for use in endoscopic organ procedures 72 2003
7,331,980 Occlusion, anchoring, tensioning and flow direction apparatus and methods for use 6 2003
 
HORIZON TECHNOLOGY FUNDING COMPANY LLC (7)
6,290,728 Designs for left ventricular conduit 73 1999
7,294,115 Methods of providing direct blood flow between a heart chamber and a coronary vessel 10 2000
6,610,100 Designs for left ventricular conduit 41 2001
6,945,949 Left ventricular conduits to coronary arteries and methods for coronary bypass 6 2002
6,949,080 Left ventricular conduits to coronary arteries and methods for coronary bypass 17 2002
7,101,402 Designs for left ventricular conduit 9 2003
6,953,481 Designs for left ventricular conduit 6 2004
 
INCEPT LLC (7)
6,152,943 Methods and apparatus for intraluminal deposition of hydrogels 67 1998
6,605,294 Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels 97 1998
6,379,373 Methods and apparatus for intraluminal deposition of hydrogels 104 1999
7,009,034 Biocompatible crosslinked polymers 30 2001
6,689,148 Methods and apparatus for intraluminal deposition of hydrogels 35 2001
7,220,270 Methods and apparatus for intraluminal deposition of hydrogels 5 2004
7,332,566 Biocompatible crosslinked polymers with visualization agents 9 2005
 
SERONO GENETICS INSTITUTE S.A. (7)
7,074,901 Isolated human vCOL16A1 polypeptide and fragments thereof 1 2001
6,989,262 Plasmin variants and uses thereof 4 2001
7,074,571 Serine carboxypeptidase hx (SCPhx) and compositions thereof 5 2001
6,794,363 Isolated amyloid inhibitor protein (APIP) and compositions thereof 15 2001
7,094,876 Human cDNAs and proteins and uses thereof 2 2001
7,122,629 Human cDNAs and proteins and uses thereof 2 2001
7,291,495 .beta.-Secretase variant 1 2004
 
WYETH (7)
5,288,711 Method of treating hyperproliferative vascular disease 138 1992
6,746,773 Coatings for medical devices 154 2001
7,195,640 Coated medical devices for the treatment of vulnerable plaque 53 2002
7,108,701 Drug releasing anastomosis devices and methods for treating anastomotic sites 41 2002
2004/0167,572 Coated medical devices 178 2003
7,056,550 Medical devices, drug coatings and methods for maintaining the drug coatings thereon 25 2003
7,303,758 Local vascular delivery of mycophenolic acid in combination with rapamycin to prevent restenosis following vascular injury 4 2004
 
ANULEX TECHNOLOGIES, INC. (6)
7,052,516 Spinal disc annulus reconstruction method and deformable spinal disc annulus stent 44 2002
7,004,970 Methods and devices for spinal disc annulus reconstruction and repair 69 2002
6,984,247 Spinal disc annulus reconstruction method and spinal disc annulus stent 32 2003
6,997,956 Spinal disc annulus reconstruction method and spinal disc annulus stent 24 2003
7,033,395 Spinal disc annulus reconstruction method and spinal disc annulus stent 22 2003
7,189,235 Spinal disc annulus reconstruction method and spinal disc annulus stent 51 2003
 
BIOTRONIK MESS-UND THERAPIEGERAETE GMBH & CO. (6)
5,935,506 Method for the manufacture of intraluminal stents of bioresorbable polymeric material 62 1996
6,579,309 Stent for vessel branchings 75 2000
6,565,598 Stent with a closed structure 11 2000
6,596,021 Stent 7 2000
6,613,080 Stent with closed structure 13 2000
6,896,695 Stent 31 2001
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (6)
6,409,750 Woven bifurcated and trifurcated stents and methods for making the same 169 2000
7,018,401 Woven intravascular devices and methods for making the same and apparatus for delivery of the same 65 2000
6,596,296 Drug releasing biodegradable fiber implant 95 2000
6,792,979 Methods for creating woven devices 77 2002
7,048,014 Methods for creating woven devices 37 2002
7,033,603 Drug releasing biodegradable fiber for delivery of therapeutics 42 2003
 
INTRATHERAPEUTICS WEST, INC. (6)
5,246,445 Device for the treatment of constricted ducts in human bodies 266 1992
5,372,600 Stent delivery systems 199 1993
5,964,771 Temporary stent system 92 1995
6,371,979 Stent delivery system 43 1997
5,782,838 Cytoscope delivery system 61 1997
6,090,115 Temporary stent system 25 1998
 
KABUSHIKIKAISHA IGAKI IRYO SEKKEI (6)
6,045,568 Luminal stent, holding structure therefor and device for attaching luminal stent 37 1997
6,080,177 Luminal stent, holding structure therefor and device for attaching luminal stent 103 1998
6,500,204 Stent for vessels 22 2000
7,066,952 Method for manufacturing yarn for vessel stent 13 2002
RE38653 Luminal stent, holding structure therefor and device for attaching luminal stent 23 2002
RE38711 Luminal stent, holding structure therefor and device for attaching luminal stent 6 2002
 
MED INSTITUTE, INC. (6)
6,096,070 Coated implantable medical device 671 1996
5,824,049 Coated implantable medical device 658 1996
5,873,904 Silver implantable medical device 657 1997
6,530,951 Silver implantable medical device 254 1997
6,299,604 Coated implantable medical device 497 1999
6,730,064 Coated implantable medical device 180 2001
 
MEDTRONIC AVE, INC. (6)
5,709,713 Radially expansible vascular prosthesis having reversible and other locking structures 195 1995
5,984,963 Endovascular stents 70 1996
5,755,772 Radially expansible vascular prosthesis having reversible and other locking structures 163 1996
6,086,611 Bifurcated stent 122 1997
6,156,062 Helically wrapped interlocking stent 115 1997
6,206,915 Drug storing and metering stent 138 1998
 
MEDTRONIC VASCULAR, INC. (6)
6,613,081 Deformable scaffolding multicellular stent 57 2001
6,878,161 Stent graft loading and deployment device and method 23 2002
7,001,421 Stent with phenoxy primer coating 37 2003
7,163,555 Drug-eluting stent for controlled drug delivery 27 2003
6,863,684 Deformable scaffolding multicellular stent 39 2003
2005/0149,174 Medical devices to treat or inhibit restenosis 2 2004
 
SCHNEIDER (USA) INC. (6)
6,042,875 Drug-releasing coatings for medical devices 316 1999
6,251,135 Radiopaque marker system and method of use 112 1999
6,626,936 Bioabsorbable marker having radiopaque constituents 51 2000
7,083,641 Radiopaque markers for implantable prostheses 5 2001
7,108,716 Stent-graft with bioabsorbable structural support 25 2003
7,211,109 Braided composite prosthesis 12 2004
 
ATTENUEX TECHNOLOGIES, INC. (5)
6,682,473 Devices and methods for attenuation of pressure waves in the body 26 2000
6,976,950 Implantable valved pressure attenuation device 12 2003
6,988,983 Implantable self-inflating attenuation device 14 2003
7,074,178 Treatment of patients with a compressible attenuation device 9 2003
6,976,951 High vapor pressure attenuation device 7 2003
 
BOSTON SCIENTIFIC NEUROMODULATION CORPORATION (5)
6,051,017 Implantable microstimulator and systems employing the same 268 1998
6,175,764 Implantable microstimulator system for producing repeatable patterns of electrical stimulation 82 2000
6,181,965 Implantable microstimulator system for prevention of disorders 82 2000
6,185,455 Method of reducing the incidence of medical complications using implantable microstimulators 119 2000
6,214,032 System for implanting a microstimulator 117 2000
 
METABOLIX, INC. (5)
6,548,569 Medical devices and applications of polyhydroxyalkanoate polymers 65 2000
6,838,493 Medical devices and applications of polyhydroxyalkanoate polymers 60 2002
6,867,247 Medical devices and applications of polyhydroxyalkanoate polymers 44 2002
7,179,883 Medical devices and applications of polyhydroxyalkanoate polymers 10 2004
7,268,205 Medical devices and applications of polyhydroxyalkanoate polymers 13 2007
 
PONIARD PHARMACEUTICALS, INC. (5)
5,770,609 Prevention and treatment of cardiovascular pathologies 81 1995
6,197,789 Prevention and treatment of cardiovascular pathologies with tamoxifen analogues 19 1997
6,251,920 Prevention and treatment of cardiovascular pathologies 15 1998
6,262,079 Prevention and treatment of cardiovascular pathologies 16 1999
6,410,587 Compounds and therapies for the prevention of vascular and non-vascular pathologies 15 2000
 
SUPERGEN, INC. (5)
6,485,514 Local delivery of therapeutic agents 11 1997
6,191,119 Combination therapy including 9-nitro-20(S)-camptothecin 11 1999
6,629,995 Camptothecin conjugates 2 2000
6,420,378 Inhibition of abnormal cell proliferation with camptothecin and combinations including the same 9 2000
6,664,233 Combination therapy including 9-nitro-20(S)-camptothecin and bleomycin 1 2000
 
AMS RESEARCH CORPORATION (4)
6,991,647 Bioresorbable stent 36 2001
7,070,556 Transobturator surgical articles and methods 67 2002
6,911,003 Transobturator surgical articles and methods 94 2003
D543626 Handle for a surgical instrument 10 2003
 
BASF AKTIENGESELLSCHAFT (4)
6,290,990 Slow-release matrix pellets and the production thereof 29 1996
6,187,342 Solid medicaments obtained by extrusion of an isomalt-containing polymer-active substance melt 12 1998
6,350,398 Process for producing coated solid dosage forms 36 1999
6,284,803 Solid dosage form with polymeric binder 15 1999
 
C.R. BARD, INC. (4)
6,432,126 Flexible vascular inducing implants 42 1998
6,692,520 Systems and methods for imbedded intramuscular implants 10 1998
6,620,170 Devices and methods for treating ischemia by creating a fibrin plug 4 1999
6,786,929 Flexible vascular inducing implants and methods 25 2001
 
J.W. MEDICAL SYSTEMS LTD. (4)
7,270,668 Apparatus and methods for delivering coiled prostheses 17 2002
7,137,993 Apparatus and methods for delivery of multiple distributed stents 26 2003
7,294,146 Apparatus and methods for delivery of variable length stents 27 2003
7,320,702 Apparatus and methods for deployment of multiple custom-length prostheses (III) 25 2005
 
SULZER INTRA THERAPEUTICS, INC. (4)
6,132,460 Stent 97 1998
6,132,461 Stent with dual support structure 93 1998
6,358,274 Stent 32 2000
6,371,953 Temporary stent system 11 2000
 
TAKEDA PHARMACEUTICAL COMPANY LIMITED (4)
6,200,958 Agent for treating high-risk impaired glucose tolerance 9 1999
6,248,357 Solid pharmaceutical preparation with improved buccal disintegrability and/or dissolubility 11 1999
6,328,994 Orally disintegrable tablets 25 1999
6,299,904 Solid pharmaceutical preparation 13 1999
 
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (4)
5,658,894 Compositions for inhibiting restenosis 15 1994
5,874,419 Compositions and methods for modulating growth of a tissue in a mammal 12 1997
5,902,799 Methods of modulating tissue growth and regeneration 29 1997
5,935,940 Compositions and methods for modulating growth of a tissue in a mammal 8 1997
 
VASCULAR CONCEPTS HOLDINGS LIMITED (4)
5,980,565 Sandwich stent 58 1997
6,517,889 Process for coating a surface of a stent 74 2001
6,641,611 Therapeutic coating for an intravascular implant 83 2001
6,821,549 Process for coating a surface of a stent 5 2002
 
CARDIOVASCULAR TECHNOLOGIES, INC. (3)
6,726,696 Patches and collars for medical applications and methods of use 115 2002
7,025,776 Arteriotomy closure devices and techniques 37 2002
7,182,771 Vascular couplers, techniques, methods, and accessories 14 2002
 
COOK MEDICAL TECHNOLOGIES LLC (3)
5,443,498 Vascular stent and method of making and implanting a vacsular stent 404 1993
7,056,337 Natural tissue stent 3 2003
7,153,324 Prosthetic valve devices and methods of making such devices 58 2004
 
CORVITA CORPORATION (3)
4,738,740 Method of forming implantable vascular grafts 118 1985
4,743,252 Composite grafts 217 1986
5,968,091 Stents and stent grafts having enhanced hoop strength and methods of making the same 199 1997
 
DATASCOPE CORP. (3)
6,165,185 Method for interconnecting vessels in a patient 112 1999
6,251,116 Device for interconnecting vessels in a patient 40 1999
6,458,140 Devices and methods for interconnecting vessels 41 2001
 
DUKE UNIVERSITY (3)
5,059,211 Absorbable vascular stent 451 1987
5,306,286 Absorbable stent 341 1991
5,527,337 Bioabsorbable stent and method of making the same 339 1994
 
FOGARTY, THOMAS J. (3)
5,830,217 Soluble fixation device and method for stent delivery catheters 106 1996
6,168,602 Soluble fairing surface for catheters 32 1998
6,391,033 Soluble fixation device and method for stent delivery catheters 29 2001
 
FOSSA MEDICAL, INC. (3)
6,214,037 Radially expanding stent 107 1999
6,709,465 Radially expanding ureteral device 9 2001
7,214,229 Radially expanding stents 6 2002
 
JPMORGAN CHASE BANK, N.A. (3)
6,682,555 Methods for treating the prostate and inhibiting obstruction of the prostatic urethra using biodegradable stents 18 2001
6,758,857 Treatment catheters with thermally insulated regions 34 2001
6,796,960 Low thermal resistance elastic sleeves for medical device balloons 51 2002
 
NFOCUS NEUROMEDICAL, INC. (3)
6,159,531 Coating having biological activity and medical implant having surface carrying the same and method 14 1999
6,371,980 Composite expandable device with impervious polymeric covering and bioactive coating thereon, delivery apparatus and method 6 1999
2002/0062,145 Composite expandable device with polymeric covering and bioactive coating thereon, delivery apparatus and method 4 2001
 
RADIANCE MEDICAL SYSTEMS, INC. (3)
5,993,374 Microcapsules for site-specific delivery 30 1997
6,120,535 Microporous tubular prosthesis 85 1997
6,261,320 Radioactive vascular liner 84 1999
 
REVA MEDICAL, INC. (3)
6,224,626 Ultra-thin expandable stent 118 1999
6,623,521 Expandable stent with sliding and locking radial elements 92 2000
6,951,053 Method of manufacturing a prosthesis 67 2003
 
TEI BIOSCIENCES, INC. (3)
5,891,558 Biopolymer foams for use in tissue repair and reconstruction 103 1996
6,153,292 Biopolymer foams for use in tissue repair and reconstruction 84 1999
6,695,879 Cardiovascular components for transplantation and methods of making thereof 2 2001
 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN (3)
5,635,386 Methods for regulating the specific lineages of cells produced in a human hematopoietic cell culture 62 1994
6,818,016 Methods for coating stents with DNA and expression of recombinant genes from DNA coated stents in vivo 2 1997
7,226,589 Treatment of diseases by site specific instillation of cells or site specific transformation of cells and kits therefor 1 1999
 
AMCELL CORPORATION (2)
5,843,633 Characterization of a human hematopoietic progenitor cell antigen 36 1996
6,455,678 Human hematopoietic stem and progenitor cell antigen 9 1997
 
ANGIOTECH INTERNATIONAL AG (2)
7,166,570 Medical implants and fibrosis-inducing agents 52 2004
7,241,736 Compositions and methods for treating diverticular disease 17 2005
 
ANGIOTECH PHARMACEUTICALS, INC. (2)
6,790,185 Sealant plug delivery methods 16 2002
7,151,135 Crosslinked polymer compositions 1 2005
 
AVE GALWAY LIMITED (2)
6,113,628 Endovascular stent with support wire 32 1997
6,056,775 Bifurcated endovascular stents and method and apparatus for their placement 175 1998
 
BIOCARDIA DEVICECO, INC. (2)
6,478,776 Implant delivery catheter system and methods for its use 47 2000
6,971,998 Implant delivery catheter system and methods for its use 12 2002
 
BIOMEDICAL RESEARCH SERVICES, INC. (2)
7,001,328 Method for using tropoelastin and for producing tropoelastin biomaterials 6 1997
6,667,051 Methods for producing elastin, and tropoelastin products for repairing and or replacing tissue 2 2001
 
BIONX IMPLANTS OY (2)
6,503,278 Under tissue conditions degradable material and a method for its manufacturing 10 1998
6,524,345 Surgical implant 22 1999
 
BIONX IMPLANTS, INC. (2)
6,569,191 Self-expanding stent with enhanced radial expansion and shape memory 91 2000
6,551,352 Method for attaching axial filaments to a self expanding stent 16 2001
 
BIOSURFACE ENGINEERING TECHNOLOGIES, INC. (2)
6,921,811 Bioactive coating composition and methods 63 2001
6,596,699 Nucleic acid coating compositions and methods 17 2002
 
BOSTON SCIENTIFIC LIMITED (2)
6,306,166 Loading and release of water-insoluble drugs 127 1998
6,335,029 Polymeric coatings for controlled delivery of active agents 332 1998
 
CERNOFINA, LLC (2)
7,087,661 Safe and effective biofilm inhibitory compounds and health-related uses thereof 23 1999
7,132,567 Generation of combinatorial synthetic libraries and screening for proadhesins and nonadhesins 8 2001
 
CONVERGE MEDICAL, INC. (2)
6,843,795 Anastomotic connector for sutureless anastomosis systems 6 2000
6,887,249 Positioning systems for sutureless anastomosis systems 20 2000
 
CORNELL RESEARCH FOUNDATION, INC. (2)
6,503,538 Elastomeric functional biodegradable copolyester amides and copolyester urethanes 132 2000
7,304,122 Elastomeric functional biodegradable copolyester amides and copolyester urethanes 1 2001
 
DEPUY SPINE, INC. (2)
6,712,852 Laminoplasty cage 69 2002
6,997,953 Method for implanting a laminoplasty 36 2004
 
ENDOLOGIX, INC. (2)
6,261,316 Single puncture bifurcation graft deployment system 124 1999
6,663,665 Single puncture bifurcation graft deployment system 37 2001
 
ENDOLUMINAL THERAPEUTICS, INC. (2)
6,443,941 Biodegradable polymeric endoluminal sealing process, apparatus and polymeric products for use therein 80 2000
6,699,272 Biodegradable polymeric endoluminal sealing process, apparatus and polymeric products for use therein 22 2001
 
HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (2)
2006/0224,531 Method and apparatus for computational analysis 3 2005
7,698,111 Method and apparatus for computational analysis 2 2005
 
INNOVATIONAL HOLDINGS LLC (2)
6,562,065 Expandable medical device with beneficial agent delivery mechanism 84 2000
7,160,321 Expandable medical device for delivery of beneficial agent 17 2004
 
KNOLL PHARMACEUTICAL COMPANY (2)
6,458,842 Liquid pharmaceutical compositions comprising thyroid hormones 41 1996
5,955,105 Stabilized thyroid hormone preparations and methods of making same 24 1996
 
LINVATEC BIOMATERIALS OY (2)
6,685,734 Urethral stent delivery system 6 1999
6,709,452 Biodegradable surgical implants 6 2000
 
LINVATEC BIOMATERIALS, INC. (2)
6,902,575 Stent delivery apparatus and method 5 2001
6,991,646 Method and apparatus for delivering a stent into a body lumen 13 2001
 
LSI SOLUTIONS, INC. (2)
5,503,635 Apparatus and method for performing compressional anastomoses 191 1993
5,611,794 Clamp for approximating tissue sections 99 1995
 
MERCK PATENT GMBH (2)
6,372,255 Tablet for instant and prolonged release of one or more active substances 43 2000
6,491,946 Pharmaceutical levothyroxine preparation 7 2001
 
MUNIN CORPORATION (2)
6,413,735 Method of screening for a modulator of angiogenesis 3 1999
6,790,606 Extracellular matrix signaling molecules 2 2000
 
NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT (2)
6,365,712 Methods and compositions for inhibiting inflammation and angiogenesis comprising a mammalian CD97 .alpha. subunit 2 1999
6,936,706 Modified antibodies with human milk fat globule specificity and uses 1 2001
 
OMEROS CORPORATION (2)
6,740,100 Tendon repair using adhesive 2 2002
7,297,348 Biodegradable triblock copolymers, synthesis methods therefore, and hydrogels and biomaterials made there from 4 2003
 
ORTHOVITA, INC. (2)
6,863,899 Composite shaped bodies and methods for their production and use 20 2002
7,189,263 Biocompatible bone graft material 23 2004
 
PDT SYSTEMS, INC. (2)
5,429,634 Biogenic implant for drug delivery and method 108 1993
5,419,760 Medicament dispensing stent for prevention of restenosis of a blood vessel 218 1994
 
QUADRANT DRUG DELIVERY LIMITED (2)
6,893,657 Solid dose delivery vehicle and methods of making same 10 2003
7,056,495 Solid dose delivery vehicle and methods of making same 82 2003
 
RADIOMED CORPORATION (2)
5,906,573 Radioactive surgical fastening devices and methods of making same 38 1997
6,030,333 Implantable radiotherapy device 76 1997
 
RHODE ISLAND HOSPITAL (2)
4,795,459 Implantable prosthetic device with lectin linked endothelial cells 37 1987
7,001,881 Tribonectins 7 2000
 
ROYALTY PHARMA FINANCE TRUST (2)
5,677,180 Chimeric antibody with specificity to human B cell surface antigen 30 1995
5,721,108 Chimeric antibody with specificity to human B cell surface antigen 34 1995
 
SALUTRIA PHARMACEUTICALS LLC (2)
6,670,398 Compounds and methods for treating transplant rejection 22 2001
7,087,645 Compounds and methods for treating transplant rejection 3 2003
 
ST. JUDE MEDICAL, INC. (2)
5,895,420 Bioresorbable heart valve support 61 1997
6,322,588 Medical devices with metal/polymer composites 90 1999
 
STEMCELL TECHNOLOGIES INC. (2)
6,342,344 Antibody composition for isolating human cells from human-murine chimeric hematopoietic cell suspensions 3 1999
2002/0177,176 Novel antibody composition for isolating human cells from human-murine chimeric hematopoietic cell suspensions 3 2002
 
STEWARD RESEARCH AND SPECIALTY PROJECTS CORPORATION (2)
5,980,887 Methods for enhancing angiogenesis with endothelial progenitor cells 66 1996
6,676,937 Compositions and methods for modulating vascularization 17 1999
 
SULZER CARBOMEDICS INC. (2)
6,416,549 Antithrombogenic annuloplasty ring having a biodegradable insert 12 1999
6,528,107 Method for producing antimicrobial antithrombogenic medical devices 18 1999
 
SURMODICS, INC. (2)
7,220,276 Endovascular graft coatings 4 2000
7,094,418 Crosslinkable macromers 4 2004
 
TEPHA, INC. (2)
6,514,515 Bioabsorbable, biocompatible polymers for tissue engineering 39 2000
6,746,685 Bioabsorbable, biocompatible polymers for tissue engineering 22 2002
 
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (2)
6,030,613 Receptor specific transepithelial transport of therapeutics 60 1997
6,485,726 Receptor specific transepithelial transport of therapeutics 82 1998
 
THE JOHNS HOPKINS UNIVERSITY (2)
6,403,675 Biodegradable compositions comprising poly(cycloaliphatic phosphoester) compounds, articles, and methods for using the same 8 1998
6,805,876 Phosphate based biodegradable polymers 4 2001
 
THORATEC CORPORATION (2)
6,752,826 Layered stent-graft and methods of making the same 146 2001
7,288,111 Flexible stent and method of making the same 8 2002
 
UNIVERSITY OF CONNECTICUT (2)
7,091,297 Shape memory polymers based on semicrystalline thermoplastic polyurethanes bearing nanostructured hard segments 9 2003
7,208,550 Blends of amorphous and semicrystalline polymers having shape memory properties 5 2003
 
UNIVERSITY OF VIRGINIA (2)
6,599,274 Cell delivery catheter and method 14 2000
2005/0070,989 Medical devices having porous layers and methods for making the same 42 2004
 
VALENTX, INC. (2)
7,037,344 Apparatus and methods for treatment of morbid obesity 181 2003
7,220,284 Gastrointestinal sleeve device and methods for treatment of morbid obesity 64 2005
 
W. L. GORE & ASSOCIATES, INC. (2)
6,551,350 Kink resistant bifurcated prosthesis 70 1996
5,916,585 Materials and method for the immobilization of bioactive species onto biodegradable polymers 73 1997
 
A.V. TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS, RUSSIAN ACADEMY OF SCIENCES (1)
5,945,457 Process for preparing biologically compatible polymers and their use in medical devices 54 1997
 
ABBOTT CARDIOVASCULAR SYSTEMS INC. (1)
7,294,334 Methods and compositions to treat myocardial conditions 28 2004
 
ABBOTT GMBH & CO. KG (1)
6,423,256 Process for producing solid dosage forms 18 1999
 
ABBOTT PARK (1)
7,235,087 Articulating suturing device and method 37 2003
 
ABSORBABLE POLYMER TECHNOLOGIES, INC. (1)
6,461,631 Biodegradable polymer composition 57 1999
 
ACCESS CLOSURE, INC. (1)
7,335,220 Apparatus and methods for sealing a vascular puncture 79 2004
 
ACUSPHERE, INC. (1)
6,395,300 Porous drug matrices and methods of manufacture thereof 95 1999
 
ADERANS RESEARCH INSTITUTE, INC. (1)
6,511,748 Bioabsorbable fibers and reinforced composites produced therefrom 85 2000
 
ADVANCED BYPASS TECHNOLOGIES, INC. (1)
6,740,101 Sutureless anastomosis systems 28 1999
 
ADVANCED LASER APPLICATIONS HOLDING S.A. (1)
7,135,039 Intraluminar perforated radially expandable drug delivery prosthesis and a method for the production thereof 25 2001
 
ADVANCED SURGICAL INTERVENTION, INC. (1)
5,160,341 Resorbable urethral stent and apparatus for its insertion 212 1990
 
AEROSPACE INDUSTRIAL DEVELOPMENT CORPORATION (1)
6,443,498 Joint engagement device for two multi-joint mechanisms 17 2001
 
AKOS BIOMEDICAL, INC. (1)
6,264,700 Prosthetic gastroesophageal valve 69 1998
 
ALARA PHARMACEUTICAL CORPORATION (1)
6,399,101 Stable thyroid hormone preparations and method of making same 20 2000
 
ALI RAZAVI (1)
5,961,547 Temporary stent 37 1997
 
ALZA CORPORATION (1)
6,071,305 Directional drug delivery stent and method of use 317 1997
 
AMERICAN HOME PRODUCTS CORPORATION (1)
4,344,934 Therapeutic compositions with enhanced bioavailability 36 1980
 
AMERSHAM HEALTH SALUTAR INC. (1)
5,688,486 Use of fullerenes in diagnostic and/or therapeutic agents 51 1994
 
ANGIODYNAMICS, INC. (1)
6,770,070 Lung treatment apparatus and method 152 2000
 
ANOVA CORP. (1)
7,273,497 Methods for treating a defect in the annulus fibrosis 23 2003
 
AP PHARMA, INC. (1)
6,946,145 Block copolymers based on poly(ortho esters) containing amine groups 3 2003
 
ARTIMPLANT AB (1)
7,037,342 Implant for reconstruction of joints 8 2002
 
ARTISAN COMPONENTS, INC. (1)
6,981,987 Removable stent for body lumens 7 2001
 
ASPECT SOFTWARE, INC. (1)
5,276,732 Remote workstation use with database retrieval system 23 1991
 
AST PRODUCTS, INC. (1)
6,844,024 Methods for coating implants 1 2003
 
ASTELLAS PHARMA INC. (1)
6,328,979 Sustained release medicinal compositions 13 2000
 
ASTRAZENECA AB (1)
6,284,271 Multiple unit effervescent dosage form 9 1998
 
ATRIX LABORATORIES, INC. (1)
6,528,080 Biodegradable polymer composition 28 2002
 
AVANTEC VASCULAR CORPORATION (1)
6,471,980 Intravascular delivery of mycophenolic acid 114 2001
 
AVENTIS PHARMACEUTICALS PRODUCTS INC. (1)
6,159,978 Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56.sup.lck tyrosine kinases 126 1998
 
BARD CONNAUGHT (1)
5,976,181 Balloon mounted stent and method therefor 61 1997
 
BASF CORPORATION (1)
6,056,975 Stabilized thyroid hormone preparations and methods of making same 25 1998
 
BAXTER INTERNATIONAL INC. (1)
6,613,070 System and method for sealing vascular penetrations with hemostatic gels 37 2001
 
BAYLOR COLLEGE OF MEDICINE (1)
7,238,363 Modification of medical prostheses 17 2005
 
BETH ISRAEL DEACONESS MEDICAL CENTER (1)
6,673,341 Methods of inhibiting proliferative diseases by inhibiting TGF-.beta.-mediated angiogenesis 3 1999
 
BIO-SEAL, LLC (1)
7,001,410 Bioabsorbable sealant 7 2003
 
BIOCOMPATIBLES UK LIMITED (1)
7,211,039 Strand with end plug 17 2006
 
BIOPSY SCIENCES, LLC (1)
7,329,414 Biodegradable polymer for marking tissue and sealing tracts 9 2002
 
BIORETEC LTD. (1)
6,277,393 Systemic and/or local (topical) application of tetracycline and/or tetracycline derivative(s) for treating, suppressing and preventing of cerebrovascular diseases, traumas and damages of nervous system 4 1999
 
BIOSENSE, INC. (1)
2003/0125,615 Homing of autologous cells to a target zone in tissue using active therapeutics or substances 24 2002
 
BIOTRONIK AG (1)
6,287,332 Implantable, bioresorbable vessel wall support, in particular coronary stent 170 1999
 
BMG INCORPORATED (1)
6,897,245 Medical materials sterilized by radiation and their ways in use 5 2002
 
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (1)
7,311,727 Encased stent 40 2004
 
BODYCOTE ORTECH INC. (1)
4,355,426 Porous flexible vascular graft 95 1979
 
BOSTON SCIENTIFIC CORP./SCIMED LIFE SYSTEMS, INC. (1)
6,554,855 Low profile, high stretch, low dilation knit prosthetic device 28 2001
 
BRAINWAVE CARDIOVASCULAR TECHNOLOGIES, LTD. (1)
6,629,993 Flexible expandable sheet stent and technology of its manufacturing 13 2001
 
BRISTOL-MYERS SQUIBB COMPANY (1)
6,331,316 Enteric coated pharmaceutical tablet and method of manufacturing 15 2000
 
BRONCUS MEDICAL INC. (1)
7,175,644 Devices and methods for maintaining collateral channels in tissue 57 2001
 
BROOKHAVEN NATIONAL LABORATORY (1)
7,166,574 Synthetic heparin-binding growth factor analogs 10 2002
 
BROWN UNIVERSITY RESEARCH FOUNDATION (1)
6,620,617 Polymeric gene delivery system 50 2001
 
BURNEY, BRYAN (1)
6,010,514 Suturing assembly and method of use 28 1998
 
CAPSUGEL BELGIUM NV (1)
6,245,350 Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process 24 1996
 
CARAG AG (1)
6,949,116 Device for plugging an opening such as in a wall of a hollow or tubular organ including biodegradable elements 11 2002
 
CARNEGIE MELLON UNIVERSITY (1)
7,049,373 Process for preparation of graft polymers 13 2001
 
CELONOVA STENT, INC. (1)
6,488,702 Bistable spring construction for a stent and other medical apparatus 112 1998
 
CEREPLAST, INC. (1)
7,138,439 Biodegradable compounds including poly(lactic acid) polymer compositions and products 6 2004
 
CHILDREN'S HOSPITAL (BOSTON) (1)
6,607,724 Compositions and methods for inhibiting angiogenesis 2 1999
 
CHILDREN'S MEDICAL CENTER CORPORATION (1)
2002/0192,730 Methods for assessing antiangiogenic agents 4 2002
 
COMMON SERVICES AGENCY (1)
5,912,177 Stem cell immobilization 16 1997
 
CONSIGLIO NAZIONALE DELLE RICERCHE (1)
7,332,113 Method for the production of a biocompatible polymer-ceramic composite material with a predetermined porosity 1 2002
 
COVALENT MEDICAL, INC. (1)
7,129,210 Tissue adhesive sealant 15 2004
 
COVIDIEN LP (1)
7,129,300 Bioabsorbable adhesive compounds and compositions 5 2002
 
CYOGRAFT TISSUE ENGINEERING, INC. (1)
6,503,273 Tissue engineered blood vessels and methods and apparatus for their manufacture 11 1999
 
CYTOMATRIX, LLC (1)
6,440,734 Methods and devices for the long-term culture of hematopoietic progenitor cells 10 2000
 
DANIELS, BRUCE A., M.D. (1)
7,214,383 Stent for delivery of drugs to the endothelium 1 2003
 
DEPUY PRODUCTS, INC. (1)
6,309,380 Drug delivery via conformal film 38 1999
 
DUNING INCORPORATED (1)
7,128,755 Expandable biodegradable polymeric stents for combined mechanical support and pharmacological or radiation therapy 13 2002
 
DURECT CORPORATION (1)
7,074,803 Opioid formulations 3 2001
 
ECOPOL, LLC (1)
5,502,158 Degradable polymer composition 171 1992
 
EDWARDS LIFESCIENCES CORPORATION (1)
6,152,141 Method for delivery of therapeutic agents to the heart 65 1997
 
ELATA PLC (1)
6,384,046 Use of 40-O-(2-hydroxy)ethylrapamycin for treatment of restenosis and other disorders 16 2000
 
ELLIS DEVELOPMENTS LTD. (1)
5,990,378 Textile surgical implants 122 1996
 
ENDOSYSTEMS LLC (1)
6,881,222 Non-foreshortening intraluminal prosthesis 39 2002
 
ENDOTEX INTERVENTIONAL SYSTEMS, INC. (1)
5,800,521 Prosthetic graft and method for aneurysm repair 76 1996
 
ENDOVASCULAR TECHNOLOGIES, INC. (1)
6,290,722 Tacky attachment method of covered materials on stents 37 2000
 
ENERGY, UNITED STATES DEPARTMENT OF (1)
5,198,263 High rate chemical vapor deposition of carbon films using fluorinated gases 39 1991
 
ENTEROMED, INC. (1)
2003/0157,071 Treatment or replacement therapy using transgenic stem cells delivered to the gut 4 2002
 
ETEX CORPORATION (1)
6,464,889 Surface modification of medical implants 15 2000
 
ETHYPHARM, INC. (1)
6,488,961 Effervescent granules and methods for their preparation 23 1999
 
EVALVE, INC. (1)
7,226,467 Fixation device delivery catheter, systems and methods of use 45 2003
 
EXXON RESEARCH AND ENGINEERING COMPANY (1)
5,292,813 Fullerene-grafted polymers and processes of making 16 1992
 
FIBRO-GEN, LTD. (1)
6,627,209 Surgical stent and method for preventing occlusion of stented vessels and conduits after implantation of stents 1 2001
 
FLOW-RITE CONTROLS, LTD. (1)
6,443,496 Connector for fluid handling system 8 2001
 
FRED HUTCHINSON CANCER RESEARCH CENTER (1)
5,830,760 Creating novel hematopoietic cell lines by expressing altered retinoic acid receptors 11 1996
 
FUISZ TECHNOLOGIES LTD. (1)
5,972,029 Remotely operable stent 50 1998
 
G. D. SEARLE & CO. (1)
5,772,992 Compositions for co-administration of interleukin-3 mutants and other cytokines and hematopoietic factors 18 1994
 
GE HEALTHCARE AS (1)
6,261,537 Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors 83 1997
 
GENENTECH, INC. (1)
2002/0032,315 ANTI-VEGF ANTIBODIES 25 1998
 
GENERAL MILLS, INC. (1)
6,190,591 Embedding and encapsulation of controlled release particles 53 1999
 
GENERAL MOTORS CORPORATION (1)
5,753,088 Method for making carbon nanotubes 120 1997
 
GENERAL VASCULAR DEVICES, LTD. (1)
5,670,161 Biodegradable stent 226 1996
 
GPC BIOTECH INC. (1)
6,413,943 Methods and reagents for inhibiting proliferation of smooth muscle cells 1 1999
 
HENNING BERLIN GMBH (1)
5,958,979 Stabilized medicaments containing thyroid hormones 9 1998
 
ILLINOIS INSTITUTE OF TECHNOLOGY (1)
6,548,025 Apparatus for generating odor upon electronic signal demand 5 2000
 
IMMUNEX CORPORATION (1)
5,199,942 Method for improving autologous transplantation 122 1991
 
INFLOW DYNAMICS (1)
6,613,083 Stent device and method 52 2001
 
INION LTD. (1)
6,607,548 Resorbable polymer compositions 38 2001
 
INNERDYNE, INC. (1)
6,575,888 Bioabsorbable brachytherapy device 55 2001
 
INTEGRATED VASCULAR INTERVENTIONAL TECHNOLOGIES, L (1)
6,248,117 Anastomosis apparatus for use in intraluminally directed vascular anastomosis 163 1999
 
INTEGRATED VASCULAR INTERVENTIONAL TECHNOLOGIES, LC (1)
7,220,268 Methods for anastomosis of a graft vessel to a side of a receiving vessel 31 2003
 
INTEL CORPORATION (1)
7,215,383 Coherent light despeckling 2 2004
 
ISOTECHNIKA INC. (1)
6,884,429 Medical devices incorporating deuterated rapamycin for controlled delivery thereof 48 2002
 
JAPAN TISSUE ENGINEERING CO., LTD. (1)
6,989,030 Transplant material and method for fabricating the same 11 2000
 
KABUSHIKIAKISHA IGAKI IRYO SEKKEI (1)
5,762,625 Luminal stent and device for inserting luminal stent 30 1994
 
KELLER, MICHAEL J. (1)
6,805,706 Stent-graft with rails 31 2003
 
KENSEY NASH BVF TECHNOLOGY, LLC (1)
7,156,880 Devices and methods for treating defects in the tissue of a living being 72 2003
 
KNOLL BV (1)
5,225,204 Stable dosage of levothyroxine sodium and process of production 30 1991
 
KONA MEDICAL, INC. (1)
6,656,136 Use of focused ultrasound for vascular sealing 51 2000
 
KONICA MINOLTA HOLDINGS, INC. (1)
6,979,071 Image recording apparatus 3 2005
 
LATHAM, DANIEL W. (1)
5,464,650 Intravascular stent and method 673 1993
 
LIPOCINE INC. (1)
6,383,471 Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents 144 1999
 
LIPOSOME TECHNOLOGY, INC. (1)
5,043,165 Novel liposome composition for sustained release of steroidal drugs 45 1988
 
LIPSOME TECHNOLOGY, INC. (1)
4,920,016 Liposomes with enhanced circulation time 105 1987
 
MAQUET CARDIOVASCULAR LLC (1)
5,851,230 Vascular graft with a heparin-containing collagen sealant 28 1996
 
MASSACHUSETTS INSTITUTE OF TECHNOLOGY (1)
6,281,015 Localized delivery of factors enhancing survival of transplanted cells 16 1994
 
MAYNE PHARMA INTERNATIONAL PTY LTD (1)
5,800,836 Pelletized pharmaceutical composition 30 1995
 
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (1)
4,553,974 Treatment of collagenous tissue with glutaraldehyde and aminodiphosphonate calcification inhibitor 87 1984
 
MEDGRAFT MICROTECH, INC. (1)
7,314,636 Biodegradable injectable implants containing glycolic acid 19 2002
 
MEDI-PHYSICS INC. (1)
6,905,455 Radioactive member and method of making 19 2001
 
MEDICAL INNOVATIVE TECHNOLOGIES R&D LIMITED PARTNERSHIP (1)
5,059,166 Intra-arterial stent with the capability to inhibit intimal hyperplasia 402 1989
 
MEDIFOCUS, INC. (1)
6,895,282 Induction heating for the delivery of thermal therapy 6 2002
 
MEDIPLEX CORPORATION, KOREA (1)
6,702,850 Multi-coated drug-eluting stent for antithrombosis and antirestenosis 46 2002
 
MEMORIAL SLOAN-KETTERING CANCER CENTER (1)
5,536,641 Monoclonal antibody specific for vascular endothelial cell antigen endoglyx-1 and uses thereof for detection of, and isolation of, vascular endothelial cells 2 1994
 
MENLO CARE, INC. (1)
5,674,241 Covered expanding mesh stent 250 1996
 
MICHAEL MACK (1)
6,464,709 Device for interconnecting vessels in a patient 27 2001
 
MICROAIRE SURGICAL INSTRUMENTS LLC (1)
7,156,862 Multi-point tension distribution system device and method of tissue approximation using that device to improve wound healing 14 2002
 
MICROSENSE CARDIOVASCULAR SYSTEMS (1996) LTD. (1)
6,331,163 Protective coating for bodily sensor 132 1999
 
MICRUS CORPORATION (1)
6,616,617 Vasoocclusive device for treatment of aneurysms 31 2001
 
MORRIS INNOVATIVE RESEARCH, INC. (1)
6,790,220 Method and apparatus for sealing access 64 2002
 
MULTI-GENE VASCULAR SYSTEMS LTD. (1)
7,175,658 Artificial vascular grafts, their construction and use 5 2002
 
NATIONAL UNIVERSITY OF SINGAPORE (1)
6,737,053 Tissue-engineered ligament 13 2000
 
NATUREWORKS LLC (1)
5,834,582 Degradable polymer composition 116 1996
 
NEC CORPORATION (1)
5,641,466 Method of purifying carbon nanotubes 87 1994
 
NEOMEND, INC. (1)
6,899,889 Biocompatible material composition adaptable to diverse therapeutic indications 12 2000
 
NEW MEXICO, UNIVERSITY OF--PATENT ADMINISTRATION (1)
5,957,938 Tissue everting needle 86 1997
 
NOERX CORPORATION (1)
6,074,659 Therapeutic inhibitor of vascular smooth muscle cells 189 1998
 
NORTHERN THERAPEUTICS INC. (1)
6,482,406 Cell-based gene therapy for the pulmonary system 7 1999
 
NORTHWESTERN UNIVERSITY (1)
5,338,571 Method of forming self-assembled, mono- and multi-layer fullerene film and coated substrates produced thereby 26 1993
 
NOVARTIS AG (1)
5,681,559 Method for producing a highly enriched population of hematopoietic stem cells 17 1995
 
NOVEN PHARMACEUTICALS, INC. (1)
6,221,383 Solubility parameter based drug delivery system and method for altering drug saturation concentration 39 1999
 
NUCRYST PHARMACEUTICALS CORP. (1)
6,939,568 Treatment of inflammatory skin conditions 13 2002
 
ORBUS MEDICAL TECHNOLOGIES, INC. (1)
2007/0055,367 Medical device with coating that promotes endothelial cell adherence and differentiation 4 2006
 
ORTHO-MCNEIL PHARMACEUTICAL, INC. (1)
6,627,246 Process for coating stents and other medical devices using super-critical carbon dioxide 38 2001
 
OSTEOTOOLS, LLC (1)
6,916,483 Bioabsorbable plugs containing drugs 8 2002
 
OTSUKA PHARMACEUTICAL CO., LTD. (1)
5,011,778 Monoclonal antibodies directed to IL-1 activated endothelial cells and medicaments employing the monoclonal antibodies 31 1989
 
PERCUSURGE, INC. (1)
5,893,867 Stent positioning apparatus and method 141 1996
 
PHARMACIA CORPORATION (1)
7,004,976 Biopolymers modified with superoxide dismutase mimics 4 2003
 
POLY-MED, INC. (1)
7,129,319 Amorphous polymeric polyaxial initiators and compliant crystalline copolymers therefrom 2 2003
 
POLYREMEDY, INC. (1)
7,105,058 Apparatus for forming a microfiber coating 11 2003
 
POLYSTEM INC. (1)
6,607,720 Genetically altered mammalian embryonic stem cells, their living progeny, and their therapeutic application for improving cardiac function after myocardial infarction 6 2000
 
PROCHON BIOTECH LTD. (1)
7,335,508 Porous plasma protein matrices and methods for preparation thereof 14 2004
 
PROGRESSIVE ANGIOPLASTY SYSTEMS, INC. (1)
5,302,168 Method and apparatus for restenosis treatment 187 1991
 
PROVIDENCE HEALTH SYSTEM - OREGON (1)
6,585,773 Insertable stent and methods of making and using same 22 2001
 
PSIVIDA INC. (1)
7,279,175 Stent coated with a sustained-release drug delivery and method for use thereof 38 2002
 
QLT USA, INC. (1)
7,128,927 Emulsions for in-situ delivery systems 3 1998
 
QUANAM MEDICAL CORPORATION (1)
6,653,426 Polymer compositions for intraluminal stent 26 2002
 
QUOREX PHARMACEUTICALS, INC. (1)
6,780,890 Compounds and methods for regulating bacterial growth and pathogenesis 10 2002
 
RAMUS MEDICAL TECHNOLOGIES (1)
5,865,723 Method and apparatus for forming vascular prostheses 90 1995
 
REDDY US THERAPEUTICS, INC. (1)
7,332,489 Methods and compositions of novel triazine compounds 1 2003
 
REFOCUS OCULAR, INC. (1)
7,008,396 Ophthalmic device and method of manufacture and use 11 2000
 
REID-ROWELL, INC., 640 TENTH STREET, ATLANTA, GEORGIA 30318, A GEORGIACORP. (1)
4,539,198 Solid pharmaceutical formulations for slow, zero order release via controlled surface erosion: expanded range 38 1983
 
RUDNICKI, MICHAEL (1)
6,120,764 Adenoviruses for control of gene expression 25 1995
 
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (1)
7,056,493 Radio-opaque polymer biomaterials 13 2003
 
S.E.T.-SMART ENDOLUMENAL TECHNOLOGIES LTD. (1)
5,925,353 Targeted radioimmunotherapy 18 1997
 
SAADAT, VAHID (1)
6,991,643 Multi-barbed device for retaining tissue in apposition and methods of use 119 2000
 
SANDERLING MANAGEMENT CO LLC (1)
5,376,376 Resorbable vascular wound dressings 110 1993
 
SANOFI-AVENTIS DEUTSCHLAND GMBH (1)
5,061,722 Cis, endo-2-azabicyclo-[3.3.0]-octane-3-carboxylic acids, a process for their preparation, agents containing these compounds and their use 10 1989
 
SCHERING CORPORATION (1)
4,587,258 Angiotensin-converting enzyme inhibitors 53 1984
 
SCIOS INC. (1)
7,244,441 Stents and intra-luminal prostheses containing map kinase inhibitors 2 2004
 
SEIKAGAKU CORPORATION (1)
6,245,897 Monoclonal antibody recognizing cell surface antigen CD14 2 1999
 
SENJU PHARMACEUTICAL CO., LTD. (1)
5,152,758 Electroresponsive hydrogel and physiologically active substance release control system 63 1990
 
SERONO GENETICS INSTITUTE, INC. (1)
7,005,500 Human cDNAs and proteins and uses thereof 1 2001
 
SHEAR/KERSHMAN LABORATORIES, INC. (1)
6,340,471 Method for preparing solid delivery system for encapsulated and non-encapsulated pharmaceuticals 14 1999
 
SHIN-ETSU CHEMICAL CO., LTD. (1)
7,189,789 Curable fluoropolyether composition and rubber article 1 2003
 
SIEMENS ENERGY, INC. (1)
6,746,755 Ceramic matrix composite structure having integral cooling passages and method of manufacture 28 2001
 
SIEMENS ENTERPRISE COMMUNICATIONS, INC. (1)
6,842,795 Methods and apparatus for shifting focus between multiple devices 14 2002
 
SKIN MEDICA, INC. (1)
7,160,726 Compositions comprising conditioned cell culture media and uses thereof 3 2002
 
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (1)
2002/0051,762 PURIFIED POPULATIONS OF ENDOTHELIAL PROGENITOR CELLS 8 1998
 
SMITH & NEPHEW, INC. (1)
7,279,008 Sheaths for implantable fixation devices 7 2003
 
SOFRADIM PRODUCTION (1)
7,331,199 Adhering prosthetic knitting fabric, method for making same and reinforcement implant for treating parietal deficiencies 2 2001
 
SPIRATION, INC. (1)
7,100,616 Bronchoscopic lung volume reduction method 50 2003
 
SPIRUS MEDICAL, INC. (1)
5,871,475 Catheter system 34 1996
 
ST. JUDE CHILDREN'S RESEARCH HOSPITAL (1)
6,500,421 In vivo selection of primitive hematopoietic cells 3 1999
 
ST. JUDE MEDICAL PUERTO RICO B.V. (1)
6,368,341 Insertion assembly and method of inserting a hemostatic closure device into an incision 57 1997
 
STRYKER NV OPERATIONS LIMITED (1)
7,229,454 Occlusive cinching devices and methods of use 3 2003
 
SUB-O, INC. (1)
6,540,735 System and method for facilitating hemostasis of blood vessel punctures with absorbable sponge 40 2000
 
SULZER BROTHERS LIMITED (1)
4,804,382 Artificial vessel 70 1987
 
SUMMERS, DAVID (1)
5,980,551 Composition and method for making a biodegradable drug delivery stent 116 1997
 
SURFACE GENESIS, INC. (1)
5,906,631 Method and device for sealing vascular puncture wounds 91 1997
 
SYNOVIS LIFE TECHNOLOGIES, INC. (1)
6,312,474 Resorbable implant materials 91 1999
 
TAKIRON CO., LTD. (1)
6,281,262 Shape-memory, biodegradable and absorbable material 102 1998
 
TECHNION RESEARCH & DEVELOPMENT CO., LTD. (1)
6,583,276 Angiogenic factors and use thereof in treating cardiovascular disease 5 1998
 
TECHNOLOGIES INTERNATIONAL INC., UNIVERSITY (1)
6,559,176 Compounds and methods for regulating bacterial growth and pathogenesis 21 2001
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (1)
7,048,939 Methods for the inhibition of neointima formation 37 2002
 
THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (1)
6,398,816 Genetic engineering of cells to enhance healing and tissue regeneration 16 2000
 
THE GENERAL HOSPITAL CORPORATION (1)
7,078,032 Delivery of therapeutic biologicals from implantable tissue matrices 3 2003
 
THE HOPE HEART INSTITUTE (1)
5,880,090 Treatment of vascular graft implants with G-CSF 13 1997
 
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (1)
5,558,903 Method for coating fullerene materials for tribology 20 1994
 
THE PENN STATE RESEARCH FOUNDATION (1)
6,682,545 System and device for preventing restenosis in body vessels 31 2000
 
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (1)
7,323,190 Cell delivery system comprising a fibrous matrix and cells 5 2004
 
THE SCRIPPS RESEARCH INSTITUTE (1)
5,492,890 Polypeptides for promoting cell attachment 28 1991
 
THERAGENICS CORPORATION (1)
6,821,296 Device for delivering a radioactive and/or drug dosage alone or in connection with a vascular stent 1 2001
 
TICONA GMBH (1)
6,211,402 Phosphinic acid aluminum salts 8 1999
 
TOKUSHU PAPER MFG. CO., LTD. (1)
6,214,163 Super microfibrillated cellulose, process for producing the same, and coated paper and tinted paper using the same 15 2000
 
TRICARDIA, LLC (1)
7,235,096 Implantable device for promoting repair of a body lumen 59 1999
 
TRUSTEES OF DARTMOUTH COLLEGE (1)
5,310,669 Fullerene coated surfaces and uses thereof 13 1992
 
TRUSTEES OF TUFTS COLLEGE (1)
7,151,139 Antimicrobial polymeric surfaces 17 2002
 
TYCO HEALTHCARE GROUP LP (1)
6,254,631 Stent with enhanced friction 12 1999
 
UEDA, MINORU (1)
6,953,482 Instrument for regenerating living organism tissue or organ 3 2002
 
UNIVERSITAT ZURICH (1)
7,074,412 Pharmaceutical composition 5 2003
 
UNIVERSITATSKLINIKUM FREIBURG (1)
6,939,381 Tube system for reconstructing of hollow organs 3 2001
 
UNIVERSITE PARIS 7 - DENIS DIDEROT (1)
5,957,975 Stent having a programmed pattern of in vivo degradation 141 1997
 
UNIVERSITY OF LEICESTER (1)
6,774,278 Coated implantable medical device 172 1998
 
UNIVERSITY OF MASSACHUSETTS (1)
7,173,096 Crosslinked polycyclooctene 3 2003
 
UNIVERSITY OF NEW MEXICO (1)
5,976,161 Tissue everting apparatus and method 160 1998
 
UNIVERSITY OF SOUTHERN CALIFORNIA (1)
6,387,663 Targeting pharmaceutical agents to injured tissues 6 1998
 
VASCULAR THERAPIES, LLC (1)
6,726,923 Apparatus and methods for preventing or treating failure of hemodialysis vascular access and other vascular grafts 45 2002
 
VEGENICS PTY LTD (1)
6,958,147 Use of VEGF-C to prevent restenosis 9 1999
 
VIACOR, INC. (1)
7,241,310 Method and apparatus for reducing mitral regurgitation 22 2003
 
VITAL ACCESS CORPORATION (1)
6,623,494 Methods and systems for intraluminally directed vascular anastomosis 45 1999
 
WALLACE, GEORGE (1)
6,964,658 System and method for facilitating hemostasis of blood vessel punctures with absorbable sponge 18 2003
 
WARNER-LAMBERT COMPANY (1)
6,499,984 Continuous production of pharmaceutical granulation 28 2000
 
WHD ELECTRONISCHE PRUEFTECHNIK (1)
6,913,626 Medical implant having bioabsorbable textured surface 25 2001
 
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (1)
5,674,722 Genetic modification of endothelial cells 39 1994
 
WILK PATENT DEVELOPMENT CORPORATION (1)
6,926,690 Transmyocardial shunt and its attachment mechanism, for left ventricular revascularization 40 2001
 
WISCONSIN ALUMNI RESEARCH FOUNDATION (1)
4,548,736 Preparation of protein films 42 1983
 
ZIMMER TECHNOLOGY, INC. (1)
7,291,169 Cartilage implant 31 2005
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (40)
4,553,542 Methods and apparatus for joining anatomical structures 188 1983
4,967,734 Energy-efficient running brace 7 1988
5,199,939 Radioactive catheter 257 1990
5,254,113 Anastomosis method 140 1992
5,342,348 Method and device for treating and enlarging body lumens 425 1992
5,292,321 Thermal balloon angioplasty with thermoplastic stent 168 1993
5,470,307 Catheter system for controllably releasing a therapeutic agent at a remote tissue site 80 1994
5,489,297 Bioprosthetic heart valve with absorbable stent 92 1994
5,603,720 Surgical method for use with transluminal dilation catheter 14 1995
5,676,685 Temporary stent 56 1995
5,733,327 Stent for liberating drug 131 1996
6,193,746 Endoprosthesis that can be percutaneously implanted in the patient's body 62 1996
6,098,479 Linear actuator and preferred application 5 1998
6,190,696 Stabilized thyroxine medications 17 1999
6,316,018 Drug-releasing coatings for medical devices 25 2000
6,613,082 Stent having cover with drug delivery capability 30 2000
6,645,241 Endoprosthesis that can be percutaneously implanted in the patient's body 17 2001
2001/0053,362 Applications of immune system tolerance to treatment of various diseases 2 2001
2002/0053,092 Nucleic acid constructs containing a cyclin A1 promoter, and kit 7 2001
2002/0056,148 Transfection, storage and transfer of male germ cells for generation of selectable transgenic stem cells 7 2001
6,544,185 Ultrasound imaging marker and method of use 24 2001
2002/0083,479 In vitro transfection, storage and transfer of male germ cells for generation of transgenic species 17 2001
2002/0133,835 Kit for transfection, storage and transfer of male germ cells for generation of transgenic species 7 2001
2002/0138,865 In vitro transfection, storage and transfer of male germ cells for generation of transgenic species & genetic therapies 7 2001
2002/0086,316 Reagents and methods useful for detecting diseases of the prostate 1 2001
6,613,084 Stent having cover with drug delivery capability 60 2001
7,022,522 Macroporous polymer scaffold containing calcium phosphate particles 11 2002
6,676,694 Method for installing a stent graft 17 2002
7,195,646 Polymeric stent useful for the treatment of the salivary gland ducts and method for using the same 1 2002
2003/0082,148 Methods and device compositions for the recruitment of cells to blood contacting surfaces in vivo 17 2002
2003/0185,794 Therapeutic angiogenic factors and methods for their use 4 2002
7,090,888 Sustained release ophthalmological device and method of making and using the same 5 2003
7,226,473 Treatment of stenotic regions 5 2003
7,074,189 Endoscopically deliverable ultrasound imaging system and method of use 4 2003
6,864,346 Moldable compositions 4 2003
2005/0187,607 Drug delivery device 8 2004
7,255,675 Devices and methods to treat a patient 66 2004
2005/0147,644 Reduced restenosis drug containing stents 2 2005
2005/0149,163 Reduced restenosis drug containing stents 3 2005
2006/0009,840 Carrier for releasing a therapeutic substance in response to the presence of an enzyme 1 2005

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