Immunoglobulin insertions, deletions and substitutions
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United States of America Patent
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Jan 24, 2012
Grant Date -
Feb 26, 2009
app pub date -
Jan 25, 2008
filing date -
Oct 21, 2004
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Abstract
An Fc variant of a parent Fc polypeptide, wherein said Fc variant exhibits altered binding to one or more FcγRs, wherein said Fc variant comprises at least one amino acid insertion in the Fc region of said parent Fc polypeptide.
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