US Patent No: 8,103,349

Number of patents in Portfolio can not be more than 2000

Neural electrode treatment

ALSO PUBLISHED AS: 20100094375

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Abstract

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An apparatus for applying a signal to a nerve for the treatment of a disorder includes a first electrode and a second electrode. Each of the electrodes is adapted to be secured to a nerve of a patient. A signal generator is electrically connected to each of the first and second electrodes. The signal generator is adapted to create a signal having a first waveform at the first electrode and a second waveform at the second electrode. The waveforms have parameters selected to block propagation of neural action potentials. The waveforms have a repeating pattern of cycles of pulses with a delay period between at least selected ones of said pulses. In one embodiment, the first and second waveforms are out of phase for a cycle of one of the waveforms to occur during a delay period of the other of the waveforms.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ENTEROMEDICS INC.ST PAUL, MN34

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Donders, Adrianus P Founex, CH 42 1842
Knudson, Mark B Shoreview, MN 205 7793
Weijand, Koen J Alfas Del Pi, ES 39 2040

Cited Art Landscape

Patent Info (Count) # Cites Year
 
EnteroMedics Inc. (29)
2004/0172,084 Method and apparatus for treatment of gastro-esophageal reflux disease (GERD) 57 2003
7,489,969 Vagal down-regulation obesity treatment 22 2003
2004/0172,085 Nerve stimulation and conduction block therapy 104 2003
2004/0172,086 Nerve conduction block treatment 57 2003
2004/0176,812 Enteric rhythm management 112 2003
7,167,750 Obesity treatment with electrically induced vagal down regulation 133 2004
7,444,183 Intraluminal electrode apparatus and method 52 2004
2005/0070,970 Movement disorder stimulation with neural block 56 2004
2005/0070,974 Obesity and eating disorder stimulation treatment with neural block 63 2004
7,844,338 High frequency obesity treatment 15 2004
2005/0038,484 Controlled vagal blockage therapy 117 2004
7,613,515 High frequency vagal blockage therapy 29 2005
2005/0131,485 High frequency vagal blockage therapy 102 2005
7,672,727 Neural electrode treatment 8 2005
7,822,486 Custom sized neural electrodes 20 2005
2007/0043,400 Neural electrode treatment 19 2005
7,630,769 GI inflammatory disease treatment 12 2007
7,693,577 Irritable bowel syndrome treatment 9 2007
7,720,540 Pancreatitis treatment 9 2007
7,986,995 Bulimia treatment 6 2007
2007/0135,846 Vagal obesity treatment 27 2007
2007/0135,856 Bulimia treatment 22 2007
2007/0135,857 GI inflammatory disease treatment 23 2007
2007/0135,858 Pancreatitis treatment 22 2007
2007/0142,870 Irritable bowel syndrome treatment 22 2007
7,729,771 Nerve stimulation and blocking for treatment of gastrointestinal disorders 11 2007
2008/0021,512 Nerve stimulation and blocking for treatment of gastrointestinal disorders 31 2007
2008/0300,654 IMPLANTABLE THERAPY SYSTEM 29 2007
7,917,226 Antenna arrangements for implantable therapy device 9 2008
 
MEDTRONIC, INC. (26)
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6,093,167 System for pancreatic stimulation and glucose measurement 172 1997
5,967,977 Transesophageal medical lead 71 1997
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6,104,955 Method and apparatus for electrical stimulation of the gastrointestinal tract 149 1997
6,083,249 Apparatus for sensing and stimulating gastrointestinal tract on-demand 199 1998
5,995,872 Method and apparatus for electrical stimulation of the gastrointestinal tract 187 1998
6,097,984 System and method of stimulation for treating gastro-esophageal reflux disease 167 1998
6,135,978 System for pancreatic stimulation and glucose measurement 314 1999
6,308,105 Medical electrical stimulation system using an electrode assembly having opposing semi-circular arms 62 1999
6,238,423 Apparatus and method for treating chronic constipation 113 1999
6,418,346 Apparatus and method for remote therapy and diagnosis in medical devices via interface systems 250 1999
6,612,983 Pancreatic secretion response to stimulation test protocol 88 2000
6,853,862 Gastroelectric stimulation for influencing pancreatic secretions 113 2000
6,261,280 Method of obtaining a measure of blood glucose 93 2000
6,532,388 Method and system for endotracheal/esophageal stimulation prior to and during a medical procedure 183 2000
6,928,320 Apparatus for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated 149 2001
7,620,454 Gastro-electric stimulation for reducing the acidity of gastric secretions or reducing the amounts thereof 13 2003
2004/0193,229 Gastric electrical stimulation for treatment of gastro-esophageal reflux disease 52 2003
2004/0236,381 Gastro-electric stimulation for reducing the acidity of gastric secretions or reducing the amounts thereof 49 2003
2004/0236,382 Gastro-electric stimulation for increasing the acidity of gastric secretions or increasing the amounts thereof 50 2003
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2006/0247,737 Alignment indication for transcutaneous energy transfer 27 2005
 
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5,231,988 Treatment of endocrine disorders by nerve stimulation 401 1991
5,215,089 Electrode assembly for nerve stimulation 186 1991
5,330,515 Treatment of pain by vagal afferent stimulation 346 1992
5,263,480 Treatment of eating disorders by nerve stimulation 378 1992
5,531,778 Circumneural electrode assembly 217 1994
5,571,150 Treatment of patients in coma by nerve stimulation 326 1994
5,540,730 Treatment of motility disorders by nerve stimulation 482 1995
5,707,400 Treating refractory hypertension by nerve stimulation 437 1995
6,587,719 Treatment of obesity by bilateral vagus nerve stimulation 245 1999
6,473,644 Method to enhance cardiac capillary growth in heart failure patients 322 1999
6,609,025 Treatment of obesity by bilateral sub-diaphragmatic nerve stimulation 220 2001
6,622,038 Treatment of movement disorders by near-diaphragmatic nerve stimulation 144 2001
6,600,956 Circumneural electrode assembly 231 2001
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2007/0027,484 Autonomic nerve stimulation to treat a pancreatic disorder 39 2005
7,620,455 Cranial nerve stimulation to treat eating disorders 15 2005
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BOSTON SCIENTIFIC NEUROMODULATION CORPORATION (9)
2002/0161,403 Deep brain stimulation system for the treatment of parkinson's disease or other disorders 5 2001
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2006/0036,293 Methods for treating gastrointestinal disorders 66 2005
 
NEURO AND CARDIAC TECHNOLOGIES, LLC (8)
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2005/0137,644 Method and system for vagal blocking and/or vagal stimulation to provide therapy for obesity and other gastrointestinal disorders 56 2005
2005/0143,787 Method and system for providing electrical pulses for neuromodulation of vagus nerve(s), using rechargeable implanted pulse generator 150 2005
2005/0149,146 Method and system to provide therapy for obesity and other medical disorders, by providing electrical pules to symapthetic nerves or vagal nerve(s) with rechargeable implanted pulse generator 106 2005
 
ALLERGAN, INC. (5)
5,437,291 Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction 216 1993
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ADVANCED NEUROMODULATION SYSTEMS, INC. (4)
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ACTIVE PROTECTIVE TECHNOLOGIES, INC. (3)
2005/0067,816 Method and apparatus for body impact protection 2004
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BIO CONTROL MEDICAL (B.C.M.) LTD. (3)
6,684,105 Treatment of disorders by unidirectional nerve stimulation 241 2001
7,346,398 Electrode assembly for nerve control 55 2004
2006/0100,668 Selective nerve fiber stimulation 81 2005
 
BIOCONTROL MEDICAL LTD. (3)
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CASE WESTERN RESERVE UNIVERSITY (3)
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ENDOVX, INC. (3)
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EMORY UNIVERSITY (2)
7,072,720 Devices and methods for vagus nerve stimulation 76 2002
7,142,910 Methods of indirectly stimulating the vagus nerve with an electrical field 52 2004
 
JPMORGAN CHASE BANK, N.A. (2)
2002/0062,071 Manual and automatic probe calibration 3 2001
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METACURE LIMITED (2)
6,571,127 Method of increasing the motility of a GI tract 201 2000
6,993,391 Acute and chronic electrical signal therapy for obesity 38 2003
 
TRANSNEURONIX, INC. (2)
5,423,872 Process and device for treating obesity and syndromes related to motor disorders of the stomach of a patient 299 1993
2002/0072,780 Method and apparatus for intentional impairment of gastric motility and /or efficiency by triggered electrical stimulation of the gastrointestinal tract with respect to the intrinsic gastric electrical activity 96 2001
 
BIOENTERIES CORPORATION (1)
5,601,604 Universal gastric band 225 1993
 
Biotronik Mess-und Therapiegeraete GmbH & Co. (1)
6,292,703 Neural electrode arrangement 108 1999
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (1)
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CARDIOCOMMAND, INC. (1)
6,148,222 Esophageal catheters and method of use 99 1998
 
CEDARS-SINAI MEDICAL CENTER (1)
6,558,708 Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia 55 2000
 
CENTER FOR INNOVATIVE TECHNOLOGY, THE (1)
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Cerebral Stimulation, Inc. (1)
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CVRX, INC. (1)
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DILORENZO BIOMEDICAL, LLC (1)
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EURO-CELTIQUE S.A. (1)
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FLINT HILLS SCIENTIFIC, LLC (1)
6,341,236 Vagal nerve stimulation techniques for treatment of epileptic seizures 374 1999
 
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2006/0212,089 Device for the desynchronization of neuronal brain activity 28 2004
 
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INNERCOOL THERAPIES, INC., A DELAWARE CORPORATION (1)
6,364,899 Heat pipe nerve cooler 100 1999
 
INTRAPACE, INC. (1)
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KNIGHT, MARTHA (1)
5,620,955 Bombesin receptor antagonists and uses thereof 30 1993
 
KOSAN BIOSCIENCES, INC. (1)
2002/0094,962 Motilide compounds 24 2001
 
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6,405,732 Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors 201 1999
 
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2006/0041,277 Methods and apparatus for renal neuromodulation 72 2005
 
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Other [Check patent profile for assignment information] (4)
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Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
SETPOINT MEDICAL CORPORATION (3)
8,412,338 Devices and methods for optimizing electrode placement for anti-inflamatory stimulation 1 2009
8,612,002 Neural stimulation devices and systems for treatment of chronic inflammation 0 2010
8,788,034 Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation 0 2012
 
EnteroMedics Inc. (2)
8,538,542 Nerve stimulation and blocking for treatment of gastrointestinal disorders 0 2011
8,538,533 Controlled vagal blockage therapy 0 2011
 
THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (1)
8,391,970 Devices and methods for inhibiting granulocyte activation by neural stimulation 1 2008

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