US Patent No: 8,103,349

Number of patents in Portfolio can not be more than 2000

Neural electrode treatment

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ALSO PUBLISHED AS: 20100094375
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Abstract

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An apparatus for applying a signal to a nerve for the treatment of a disorder includes a first electrode and a second electrode. Each of the electrodes is adapted to be secured to a nerve of a patient. A signal generator is electrically connected to each of the first and second electrodes. The signal generator is adapted to create a signal having a first waveform at the first electrode and a second waveform at the second electrode. The waveforms have parameters selected to block propagation of neural action potentials. The waveforms have a repeating pattern of cycles of pulses with a delay period between at least selected ones of said pulses. In one embodiment, the first and second waveforms are out of phase for a cycle of one of the waveforms to occur during a delay period of the other of the waveforms.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ENTEROMEDICS INC.ST PAUL, MN32

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Donders, Adrianus P Founex, CH 39 1615
Knudson, Mark B Shoreview, MN 200 7005
Weijand, Koen J Alfas Del Pi, ES 39 1827

Cited Art Landscape

Patent Info (Count) # Cites Year
 
EnteroMedics Inc. (29)
2004/0172,084 Method and apparatus for treatment of gastro-esophageal reflux disease (GERD) 47 2003
7,489,969 Vagal down-regulation obesity treatment 19 2003
2004/0172,085 Nerve stimulation and conduction block therapy 92 2003
2004/0172,086 Nerve conduction block treatment 51 2003
2004/0176,812 Enteric rhythm management 101 2003
7,167,750 Obesity treatment with electrically induced vagal down regulation 108 2004
7,444,183 Intraluminal electrode apparatus and method 33 2004
2005/0070,970 Movement disorder stimulation with neural block 48 2004
2005/0070,974 Obesity and eating disorder stimulation treatment with neural block 55 2004
7,844,338 High frequency obesity treatment 8 2004
2005/0038,484 Controlled vagal blockage therapy 104 2004
7,613,515 High frequency vagal blockage therapy 22 2005
2005/0131,485 High frequency vagal blockage therapy 91 2005
7,672,727 Neural electrode treatment 7 2005
7,822,486 Custom sized neural electrodes 16 2005
2007/0043,400 Neural electrode treatment 17 2005
7,630,769 GI inflammatory disease treatment 10 2007
7,693,577 Irritable bowel syndrome treatment 8 2007
7,720,540 Pancreatitis treatment 8 2007
7,986,995 Bulimia treatment 4 2007
2007/0135,846 Vagal obesity treatment 24 2007
2007/0135,856 Bulimia treatment 19 2007
2007/0135,857 GI inflammatory disease treatment 20 2007
2007/0135,858 Pancreatitis treatment 19 2007
2007/0142,870 Irritable bowel syndrome treatment 19 2007
7,729,771 Nerve stimulation and blocking for treatment of gastrointestinal disorders 8 2007
2008/0021,512 Nerve stimulation and blocking for treatment of gastrointestinal disorders 25 2007
2008/0300,654 IMPLANTABLE THERAPY SYSTEM 24 2007
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MEDTRONIC, INC. (26)
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5,967,977 Transesophageal medical lead 68 1997
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6,083,249 Apparatus for sensing and stimulating gastrointestinal tract on-demand 177 1998
5,995,872 Method and apparatus for electrical stimulation of the gastrointestinal tract 166 1998
6,097,984 System and method of stimulation for treating gastro-esophageal reflux disease 156 1998
6,135,978 System for pancreatic stimulation and glucose measurement 276 1999
6,308,105 Medical electrical stimulation system using an electrode assembly having opposing semi-circular arms 56 1999
6,238,423 Apparatus and method for treating chronic constipation 98 1999
6,418,346 Apparatus and method for remote therapy and diagnosis in medical devices via interface systems 228 1999
6,612,983 Pancreatic secretion response to stimulation test protocol 84 2000
6,853,862 Gastroelectric stimulation for influencing pancreatic secretions 103 2000
6,261,280 Method of obtaining a measure of blood glucose 85 2000
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7,620,454 Gastro-electric stimulation for reducing the acidity of gastric secretions or reducing the amounts thereof 6 2003
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2004/0236,382 Gastro-electric stimulation for increasing the acidity of gastric secretions or increasing the amounts thereof 44 2003
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5,215,089 Electrode assembly for nerve stimulation 168 1991
5,330,515 Treatment of pain by vagal afferent stimulation 312 1992
5,263,480 Treatment of eating disorders by nerve stimulation 335 1992
5,531,778 Circumneural electrode assembly 190 1994
5,571,150 Treatment of patients in coma by nerve stimulation 289 1994
5,540,730 Treatment of motility disorders by nerve stimulation 426 1995
5,707,400 Treating refractory hypertension by nerve stimulation 379 1995
6,587,719 Treatment of obesity by bilateral vagus nerve stimulation 210 1999
6,473,644 Method to enhance cardiac capillary growth in heart failure patients 278 1999
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6,600,956 Circumneural electrode assembly 201 2001
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BOSTON SCIENTIFIC NEUROMODULATION CORPORATION (14)
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2006/0036,293 Methods for treating gastrointestinal disorders 56 2005
 
NEURO AND CARDIAC TECHNOLOGIES, LLC (8)
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2003/0212,440 Method and system for modulating the vagus nerve (10th cranial nerve) using modulated electrical pulses with an inductively coupled stimulation system 138 2002
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2005/0137,644 Method and system for vagal blocking and/or vagal stimulation to provide therapy for obesity and other gastrointestinal disorders 49 2005
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ALLERGAN, INC. (5)
5,437,291 Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction 207 1993
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ADVANCED NEUROMODULATION SYSTEMS, INC. (4)
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BIOCONTROL MEDICAL LTD. (4)
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CASE WESTERN RESERVE UNIVERSITY (3)
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BIO CONTROL MEDICAL (B.C.M.) LTD. (2)
6,684,105 Treatment of disorders by unidirectional nerve stimulation 211 2001
7,346,398 Electrode assembly for nerve control 42 2004
 
EMORY UNIVERSITY (2)
7,072,720 Devices and methods for vagus nerve stimulation 66 2002
7,142,910 Methods of indirectly stimulating the vagus nerve with an electrical field 43 2004
 
METACURE LIMITED (2)
6,571,127 Method of increasing the motility of a GI tract 169 2000
6,993,391 Acute and chronic electrical signal therapy for obesity 34 2003
 
TRANSNEURONIX, INC. (2)
5,423,872 Process and device for treating obesity and syndromes related to motor disorders of the stomach of a patient 277 1993
2002/0072,780 Method and apparatus for intentional impairment of gastric motility and /or efficiency by triggered electrical stimulation of the gastrointestinal tract with respect to the intrinsic gastric electrical activity 89 2001
 
BIOENTERIES CORPORATION (1)
5,601,604 Universal gastric band 202 1993
 
Biotronik Mess-und Therapiegeraete GmbH & Co. (1)
6,292,703 Neural electrode arrangement 93 1999
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (1)
6,826,428 Gastrointestinal electrical stimulation 146 2002
 
CARDIOCOMMAND, INC. (1)
6,148,222 Esophageal catheters and method of use 95 1998
 
CEDARS-SINAI MEDICAL CENTER (1)
6,558,708 Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia 50 2000
 
CENTER FOR INNOVATIVE TECHNOLOGY, THE (1)
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Cerebral Stimulation, Inc. (1)
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CVRX, INC. (1)
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DILORENZO BIOMEDICAL, LLC (1)
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EURO-CELTIQUE S.A. (1)
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FLINT HILLS SCIENTIFIC, LLC (1)
6,341,236 Vagal nerve stimulation techniques for treatment of epileptic seizures 325 1999
 
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2006/0212,089 Device for the desynchronization of neuronal brain activity 26 2004
 
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5,226,429 Laparoscopic gastric band and method 332 1991
 
INNERCOOL THERAPIES, INC., A DELAWARE CORPORATION (1)
6,364,899 Heat pipe nerve cooler 97 1999
 
INTRAPACE, INC. (1)
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KNIGHT, MARTHA (1)
5,620,955 Bombesin receptor antagonists and uses thereof 29 1993
 
KOSAN BIOSCIENCES, INC. (1)
2002/0094,962 Motilide compounds 23 2001
 
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Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
EnteroMedics Inc. (2)
8,538,542 Nerve stimulation and blocking for treatment of gastrointestinal disorders 0 2011
8,538,533 Controlled vagal blockage therapy 0 2011
 
SETPOINT MEDICAL CORPORATION (2)
8,412,338 Devices and methods for optimizing electrode placement for anti-inflamatory stimulation 1 2009
8,612,002 Neural stimulation devices and systems for treatment of chronic inflammation 0 2010
 
THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (1)
8,391,970 Devices and methods for inhibiting granulocyte activation by neural stimulation 1 2008

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