US Patent No: 8,103,349

Number of patents in Portfolio can not be more than 2000

Neural electrode treatment

ALSO PUBLISHED AS: 20100094375
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Abstract

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An apparatus for applying a signal to a nerve for the treatment of a disorder includes a first electrode and a second electrode. Each of the electrodes is adapted to be secured to a nerve of a patient. A signal generator is electrically connected to each of the first and second electrodes. The signal generator is adapted to create a signal having a first waveform at the first electrode and a second waveform at the second electrode. The waveforms have parameters selected to block propagation of neural action potentials. The waveforms have a repeating pattern of cycles of pulses with a delay period between at least selected ones of said pulses. In one embodiment, the first and second waveforms are out of phase for a cycle of one of the waveforms to occur during a delay period of the other of the waveforms.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ENTEROMEDICS INC.ST PAUL, MN35

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Donders, Adrianus P Founex, CH 42 1938
Knudson, Mark B Shoreview, MN 208 8084
Weijand, Koen J Alfas Del Pi, ES 39 2107

Cited Art Landscape

Patent Info (Count) # Cites Year
 
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2004/0172,084 Method and apparatus for treatment of gastro-esophageal reflux disease (GERD) 59 2003
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2004/0172,085 Nerve stimulation and conduction block therapy 112 2003
2004/0172,086 Nerve conduction block treatment 60 2003
2004/0176,812 Enteric rhythm management 120 2003
7,167,750 Obesity treatment with electrically induced vagal down regulation 155 2004
7,444,183 Intraluminal electrode apparatus and method 57 2004
2005/0070,970 Movement disorder stimulation with neural block 64 2004
2005/0070,974 Obesity and eating disorder stimulation treatment with neural block 69 2004
7,844,338 High frequency obesity treatment 17 2004
2005/0038,484 Controlled vagal blockage therapy 127 2004
7,613,515 High frequency vagal blockage therapy 30 2005
2005/0131,485 High frequency vagal blockage therapy 114 2005
7,672,727 Neural electrode treatment 9 2005
7,822,486 Custom sized neural electrodes 24 2005
2007/0043,400 Neural electrode treatment 21 2005
7,630,769 GI inflammatory disease treatment 13 2007
7,693,577 Irritable bowel syndrome treatment 10 2007
7,720,540 Pancreatitis treatment 10 2007
7,986,995 Bulimia treatment 7 2007
2007/0135,846 Vagal obesity treatment 31 2007
2007/0135,856 Bulimia treatment 25 2007
2007/0135,857 GI inflammatory disease treatment 25 2007
2007/0135,858 Pancreatitis treatment 24 2007
2007/0142,870 Irritable bowel syndrome treatment 24 2007
7,729,771 Nerve stimulation and blocking for treatment of gastrointestinal disorders 12 2007
2008/0021,512 Nerve stimulation and blocking for treatment of gastrointestinal disorders 33 2007
2008/0300,654 IMPLANTABLE THERAPY SYSTEM 32 2007
7,917,226 Antenna arrangements for implantable therapy device 12 2008
 
MEDTRONIC, INC. (26)
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5,967,977 Transesophageal medical lead 72 1997
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6,104,955 Method and apparatus for electrical stimulation of the gastrointestinal tract 153 1997
6,083,249 Apparatus for sensing and stimulating gastrointestinal tract on-demand 209 1998
5,995,872 Method and apparatus for electrical stimulation of the gastrointestinal tract 201 1998
6,097,984 System and method of stimulation for treating gastro-esophageal reflux disease 171 1998
6,135,978 System for pancreatic stimulation and glucose measurement 324 1999
6,308,105 Medical electrical stimulation system using an electrode assembly having opposing semi-circular arms 66 1999
6,238,423 Apparatus and method for treating chronic constipation 127 1999
6,418,346 Apparatus and method for remote therapy and diagnosis in medical devices via interface systems 260 1999
6,612,983 Pancreatic secretion response to stimulation test protocol 91 2000
6,853,862 Gastroelectric stimulation for influencing pancreatic secretions 117 2000
6,261,280 Method of obtaining a measure of blood glucose 94 2000
6,532,388 Method and system for endotracheal/esophageal stimulation prior to and during a medical procedure 192 2000
6,928,320 Apparatus for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated 168 2001
7,620,454 Gastro-electric stimulation for reducing the acidity of gastric secretions or reducing the amounts thereof 16 2003
2004/0193,229 Gastric electrical stimulation for treatment of gastro-esophageal reflux disease 56 2003
2004/0236,381 Gastro-electric stimulation for reducing the acidity of gastric secretions or reducing the amounts thereof 56 2003
2004/0236,382 Gastro-electric stimulation for increasing the acidity of gastric secretions or increasing the amounts thereof 56 2003
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5,231,988 Treatment of endocrine disorders by nerve stimulation 420 1991
5,215,089 Electrode assembly for nerve stimulation 197 1991
5,330,515 Treatment of pain by vagal afferent stimulation 364 1992
5,263,480 Treatment of eating disorders by nerve stimulation 398 1992
5,531,778 Circumneural electrode assembly 228 1994
5,571,150 Treatment of patients in coma by nerve stimulation 344 1994
5,540,730 Treatment of motility disorders by nerve stimulation 503 1995
5,707,400 Treating refractory hypertension by nerve stimulation 465 1995
6,587,719 Treatment of obesity by bilateral vagus nerve stimulation 263 1999
6,473,644 Method to enhance cardiac capillary growth in heart failure patients 342 1999
6,609,025 Treatment of obesity by bilateral sub-diaphragmatic nerve stimulation 237 2001
6,622,038 Treatment of movement disorders by near-diaphragmatic nerve stimulation 157 2001
6,600,956 Circumneural electrode assembly 247 2001
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2007/0027,484 Autonomic nerve stimulation to treat a pancreatic disorder 44 2005
7,620,455 Cranial nerve stimulation to treat eating disorders 16 2005
2007/0100,377 Providing multiple signal modes for a medical device 15 2005
 
BOSTON SCIENTIFIC NEUROMODULATION CORPORATION (9)
2002/0161,403 Deep brain stimulation system for the treatment of parkinson's disease or other disorders 5 2001
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6,832,114 Systems and methods for modulation of pancreatic endocrine secretion and treatment of diabetes 190 2001
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2006/0036,293 Methods for treating gastrointestinal disorders 70 2005
 
NEURO AND CARDIAC TECHNOLOGIES, LLC (8)
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2003/0212,440 Method and system for modulating the vagus nerve (10th cranial nerve) using modulated electrical pulses with an inductively coupled stimulation system 167 2002
7,076,307 Method and system for modulating the vagus nerve (10th cranial nerve) with electrical pulses using implanted and external components, to provide therapy neurological and neuropsychiatric disorders 75 2004
2005/0137,644 Method and system for vagal blocking and/or vagal stimulation to provide therapy for obesity and other gastrointestinal disorders 62 2005
2005/0143,787 Method and system for providing electrical pulses for neuromodulation of vagus nerve(s), using rechargeable implanted pulse generator 161 2005
2005/0149,146 Method and system to provide therapy for obesity and other medical disorders, by providing electrical pules to symapthetic nerves or vagal nerve(s) with rechargeable implanted pulse generator 109 2005
 
ALLERGAN, INC. (5)
5,437,291 Method for treating gastrointestinal muscle disorders and other smooth muscle dysfunction 226 1993
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ADVANCED NEUROMODULATION SYSTEMS, INC. (4)
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2006/0190,053 Neural stimulation for treatment of metabolic syndrome and type 2 diabetes 35 2006
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BIO CONTROL MEDICAL (B.C.M.) LTD. (4)
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2006/0100,668 Selective nerve fiber stimulation 92 2005
 
ACTIVE PROTECTIVE TECHNOLOGIES, INC. (3)
2005/0067,816 Method and apparatus for body impact protection 1 2004
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CASE WESTERN RESERVE UNIVERSITY (3)
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4,702,254 Neurocybernetic prosthesis 410 1985
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ENDOVX, INC. (3)
2004/0181,178 Methods and apparatus for treatment of obesity 37 2003
2005/0203,501 Methods and apparatus for treatment of obesity with an ultrasound device movable in two or three axes 45 2005
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BIOCONTROL MEDICAL LTD. (2)
2003/0045,909 Selective nerve fiber stimulation for treating heart conditions 259 2002
2005/0267,542 Techniques for applying, configuring, and coordinating nerve fiber stimulation 78 2005
 
EMORY UNIVERSITY (2)
7,072,720 Devices and methods for vagus nerve stimulation 81 2002
7,142,910 Methods of indirectly stimulating the vagus nerve with an electrical field 56 2004
 
JPMORGAN CHASE BANK, N.A. (2)
2002/0062,071 Manual and automatic probe calibration 6 2001
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METACURE LIMITED (2)
6,571,127 Method of increasing the motility of a GI tract 218 2000
6,993,391 Acute and chronic electrical signal therapy for obesity 39 2003
 
TRANSNEURONIX, INC. (2)
5,423,872 Process and device for treating obesity and syndromes related to motor disorders of the stomach of a patient 304 1993
2002/0072,780 Method and apparatus for intentional impairment of gastric motility and /or efficiency by triggered electrical stimulation of the gastrointestinal tract with respect to the intrinsic gastric electrical activity 101 2001
 
BIOENTERIES CORPORATION (1)
5,601,604 Universal gastric band 238 1993
 
Biotronik Mess-und Therapiegeraete GmbH & Co. (1)
6,292,703 Neural electrode arrangement 112 1999
 
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (1)
6,826,428 Gastrointestinal electrical stimulation 175 2002
 
CARDIOCOMMAND, INC. (1)
6,148,222 Esophageal catheters and method of use 101 1998
 
CEDARS-SINAI MEDICAL CENTER (1)
6,558,708 Methods for manipulating upper gastrointestinal transit, blood flow, and satiety, and for treating visceral hyperalgesia 56 2000
 
CENTER FOR INNOVATIVE TECHNOLOGY, THE (1)
5,716,385 Crural diaphragm pacemaker and method for treating esophageal reflux disease 89 1996
 
Cerebral Stimulation, Inc. (1)
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CVRX, INC. (1)
2004/0254,616 Stimulus regimens for cardiovascular reflex control 133 2004
 
DILORENZO BIOMEDICAL, LLC (1)
2003/0018,367 Method and apparatus for neuromodulation and phsyiologic modulation for the treatment of metabolic and neuropsychiatric disease 189 2002
 
EURO-CELTIQUE S.A. (1)
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FLINT HILLS SCIENTIFIC, LLC (1)
6,341,236 Vagal nerve stimulation techniques for treatment of epileptic seizures 405 1999
 
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2006/0212,089 Device for the desynchronization of neuronal brain activity 30 2004
 
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5,226,429 Laparoscopic gastric band and method 378 1991
 
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6,364,899 Heat pipe nerve cooler 101 1999
 
INTRAPACE, INC. (1)
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5,620,955 Bombesin receptor antagonists and uses thereof 31 1993
 
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2002/0094,962 Motilide compounds 25 2001
 
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2003/0181,959 Wireless electric modulation of sympathetic nervous system 79 2002
 
MEDERI THERAPEUTICS, INC. (1)
6,405,732 Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors 214 1999
 
MEDICAL UNIVERSITY OF SOUTH CAROLINA (1)
5,830,434 Methods of treating non-insulin dependent diabetes mellitus with pancreatic polypeptide 24 1997
 
MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L. (1)
2006/0041,277 Methods and apparatus for renal neuromodulation 79 2005
 
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Other [Check patent profile for assignment information] (4)
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Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
SETPOINT MEDICAL CORPORATION (5)
8,412,338 Devices and methods for optimizing electrode placement for anti-inflamatory stimulation 2 2009
8,886,339 Nerve cuff with pocket for leadless stimulator 0 2010
8,612,002 Neural stimulation devices and systems for treatment of chronic inflammation 1 2010
8,788,034 Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation 0 2012
8,855,767 Neural stimulation devices and systems for treatment of chronic inflammation 0 2013
 
EnteroMedics Inc. (2)
8,538,542 Nerve stimulation and blocking for treatment of gastrointestinal disorders 0 2011
8,538,533 Controlled vagal blockage therapy 0 2011
 
THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH (1)
8,391,970 Devices and methods for inhibiting granulocyte activation by neural stimulation 2 2008

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