Method and medicament for inhibiting the expression of a given gene

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United States of America Patent

PATENT NO 8114851
APP PUB NO 20080233651A1
SERIAL NO

11982434

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to the specific inhibition of expression of a target gene in mammals using a short double stranded RNA. The dsRNA is less than 49 nucleotides in length and has a nucleotide sequence which is complementary to at least a part of the target gene. The dsRNAs of the present invention are useful for treating diseases, for example, cancer, viral diseases or neurodegenerative diseases.

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Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INC675 WEST KENDALL STREET HENRI A TERMEER SQUARE CAMBRIDGE MA 02142

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kreutzer, Roland Weidenberg, DE 41 1655
Limmer, Stefan Neudrossenfeld, DE 43 1729

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