Process for pure montelukast sodium through pure intermediates as well as amine salts
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United States of America Patent
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Feb 14, 2012
Grant Date -
Mar 4, 2010
app pub date -
Nov 19, 2007
filing date -
Nov 20, 2006
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Expired
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Abstract
The present invention provides an improved process for the preparation of highly pure montelukast sodium through highly pure diol intermediate compound of formula (2) and (1)-(mercapto methyl)cyclopropane acetic acid methyl ester compound of formula (4) or mercaptomethyl cyclopropane acetic acid compound of formula (7). The present invention also provides novel organic amine salts of montelukast.
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