RGD peptide attached to bioabsorbable stents
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United States of America Patent
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Feb 21, 2012
Grant Date -
Jun 19, 2008
app pub date -
Feb 21, 2008
filing date -
Jun 14, 2006
priority date (Note) -
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Abstract
Provided herein is a method of forming medical device that includes RGD attached to the device via a spacer compound. The method comprises providing a spacer compound comprising a hydrophobic moiety and a hydrophilic moiety, grafting or embedding the spacer compound to the surface layer of the polymer to cause the hydrophobic moiety to be grafted to or embedded within the surface layer of polymer, and attaching a chemo-attractant to the hydrophilic moiety.
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