Solid oral dosage form containing an enhancer
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United States of America Patent
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Feb 21, 2012
Grant Date -
Aug 23, 2007
app pub date -
Apr 7, 2006
filing date -
Feb 22, 1999
priority date (Note) -
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Abstract
The invention relates to a pharmaceutical composition and oral dosage forms comprising a bisphosphonate in combination with an enhancer to promote absorption of the bisphosphonate at the GIT cell lining. The enhancer is a medium chain fatty acid or a medium chain fatty acid derivative having a carbon chain length of from 6 to 20 carbon atoms. Preferably, the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form.
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